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Ion Channels in Innate and Adaptive Immunity

Annual review of immunology, 2015-01, Vol.33 (1), p.291-353

2015

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Ion channels and transporters in lymphocyte function and immunity

Nature reviews. Immunology, 2012-07, Vol.12 (7), p.532-547

2012

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Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4+ T Cells

Molecular cell, 2016-08, Vol.63 (3), p.457-469

2016

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Phosphatidlyinositol-3-kinase C2 beta (PI3KC2β) is a potential new target to treat IgE mediated disease

PloS one, 2017-08, Vol.12 (8), p.e0183474-e0183474

2017

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Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.3911-3911

2014

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Metabolic Inflexibility Impairs Insulin Secretion and Results In MODY-like Diabetes in Triple FoxO-Deficient Mice

Cell metabolism, 2014-10, Vol.20 (4), p.593-602

2014

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Regulation of the epithelial Ca²⁺ channel TRPV5 by reversible histidine phosphorylation mediated by NDPK-B and PHPT1

Molecular biology of the cell, 2014-04, Vol.25 (8), p.1244-1250

2014

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Inhibition of the K⁺ channel KCa3.1 ameliorates T cell-mediated colitis

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (4), p.1541-1546

2010

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Discoidin Domain Receptor 1 (DDR1) tyrosine kinase is upregulated in PKD kidneys but does not play a role in the pathogenesis of polycystic kidney disease

PloS one, 2019-07, Vol.14 (7), p.e0211670-e0211670

2019

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p38 and a p38-Interacting Protein Are Critical for Downregulation of E-Cadherin during Mouse Gastrulation

Cell, 2006-06, Vol.125 (5), p.957-969

2006

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Histidine phosphorylation relieves copper inhibition in the mammalian potassium channel KCa3.1

eLife, 2016-08, Vol.5

2016

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Protein histidine phosphatase 1 negatively regulates CD4 T cells by inhibiting the K⁺ channel KCa3.1

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (38), p.14442-14446

2008

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Phosphatidylinositol-3-Kinase C2β and TRIM27 Function To Positively and Negatively Regulate IgE Receptor Activation of Mast Cells

Molecular and Cellular Biology, 2012-08, Vol.32 (15), p.3132-3139

2012

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Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2β

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (50), p.20072-20077

2011

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A Pilot Clinical Study to Evaluate Changes in Urine Osmolality and Urine cAMP in Response to Acute and Chronic Water Loading in Autosomal Dominant Polycystic Kidney Disease

Clinical journal of the American Society of Nephrology, 2010-04, Vol.5 (4), p.693-697

2010

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Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

The EMBO journal, 1998-09, Vol.17 (18), p.5374-5387

1998

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Nucleoside Diphosphate Kinase B Knock-out Mice Have Impaired Activation of the K+ Channel KCa3.1, Resulting in Defective T Cell Activation

The Journal of biological chemistry, 2010-12, Vol.285 (50), p.38765-38771

2010

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Phosphatidylinositol 3-phosphate indirectly activates KCa3.1 via 14 amino acids in the carboxy terminus of KCa3.1

Molecular biology of the cell, 2006-01, Vol.17 (1), p.146-154

2006

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PLCε1 regulates SDF-1α–induced lymphocyte adhesion and migration to sites of inflammation

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.2693-2698

2017

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Glutamine metabolism via glutaminase 1 in autosomal-dominant polycystic kidney disease

Nephrology, dialysis, transplantation, 2018-08, Vol.33 (8), p.1343-1353

2018

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PLC epsilon 1 regulates SDF-1 alpha -induced lymphocyte adhesion and migration to sites of inflammation

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.2693-2693

2017

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Regulation of KATP Channel Trafficking in Pancreatic β-Cells by Protein Histidine Phosphorylation

Diabetes (New York, N.Y.), 2018-05, Vol.67 (5), p.849-860

2018

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Regulation of K ATP Channel Trafficking in Pancreatic β-Cells by Protein Histidine Phosphorylation

Diabetes (New York, N.Y.), 2018-05, Vol.67 (5), p.849

2018

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Phosphatidylinositol-3 Phosphatase Myotubularin-Related Protein 6 Negatively Regulates CD4 T Cells

Molecular and Cellular Biology, 2006-08, Vol.26 (15), p.5595-5602

2006

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The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy

Kidney international, 2011-10, Vol.80 (7), p.719-730

2011

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Ion Channels in Innate and Adaptive Immunity

Ion channels and transporters in lymphocyte function and immunity

Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4+ T Cells

Phosphatidlyinositol-3-kinase C2 beta (PI3KC2β) is a potential new target to treat IgE mediated disease

Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis

Metabolic Inflexibility Impairs Insulin Secretion and Results In MODY-like Diabetes in Triple FoxO-Deficient Mice

Regulation of the epithelial Ca²⁺ channel TRPV5 by reversible histidine phosphorylation mediated by NDPK-B and PHPT1

Inhibition of the K⁺ channel KCa3.1 ameliorates T cell-mediated colitis

Discoidin Domain Receptor 1 (DDR1) tyrosine kinase is upregulated in PKD kidneys but does not play a role in the pathogenesis of polycystic kidney disease

p38 and a p38-Interacting Protein Are Critical for Downregulation of E-Cadherin during Mouse Gastrulation

Histidine phosphorylation relieves copper inhibition in the mammalian potassium channel KCa3.1

Protein histidine phosphatase 1 negatively regulates CD4 T cells by inhibiting the K⁺ channel KCa3.1

Phosphatidylinositol-3-Kinase C2β and TRIM27 Function To Positively and Negatively Regulate IgE Receptor Activation of Mast Cells

Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2β

A Pilot Clinical Study to Evaluate Changes in Urine Osmolality and Urine cAMP in Response to Acute and Chronic Water Loading in Autosomal Dominant Polycystic Kidney Disease

Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

Nucleoside Diphosphate Kinase B Knock-out Mice Have Impaired Activation of the K+ Channel KCa3.1, Resulting in Defective T Cell Activation

Phosphatidylinositol 3-phosphate indirectly activates KCa3.1 via 14 amino acids in the carboxy terminus of KCa3.1

PLCε1 regulates SDF-1α–induced lymphocyte adhesion and migration to sites of inflammation

Glutamine metabolism via glutaminase 1 in autosomal-dominant polycystic kidney disease

PLC epsilon 1 regulates SDF-1 alpha -induced lymphocyte adhesion and migration to sites of inflammation

Regulation of KATP Channel Trafficking in Pancreatic β-Cells by Protein Histidine Phosphorylation

Regulation of K ATP Channel Trafficking in Pancreatic β-Cells by Protein Histidine Phosphorylation

Phosphatidylinositol-3 Phosphatase Myotubularin-Related Protein 6 Negatively Regulates CD4 T Cells

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy

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