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Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres

Organic process research & development, 2012-01, Vol.16 (1), p.26-34

2012

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Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease

Cell reports (Cambridge), 2012-11, Vol.2 (5), p.1137-1142

2012

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Deciphering of Mitochondrial Cardiolipin Oxidative Signaling in Cerebral Ischemia-Reperfusion

Journal of cerebral blood flow and metabolism, 2015-02, Vol.35 (2), p.319-328

2015

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Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria

Organic & biomolecular chemistry, 2013-07, Vol.11 (25), p.4147-4153

2013

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An Uncharged Oxetanyl Sulfoxide as a Covalent Modifier for Improving Aqueous Solubility

ACS medicinal chemistry letters, 2014-08, Vol.5 (8), p.900-904

2014

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Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death

The Journal of pharmacology and experimental therapeutics, 2013-12, Vol.347 (3), p.669

2013

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Enantioselective synthesis and selective functionalization of 4‐aminotetrahydroquinolines as novel GLP‐1 secretagogues

Chirality (New York, N.Y.), 2022-03, Vol.34 (3), p.521-536

2022

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Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats

Journal of molecular and cellular cardiology, 2014-12, Vol.77, p.136-146

2014

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Pharmacological Mitigation of Tissue Damage during Brain Microdialysis

Analytical chemistry (Washington), 2013-09, Vol.85 (17), p.8173-8179

2013

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Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors

Frontiers in oncology, 2014, Vol.4, p.24

2014

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A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage

Journal of investigative dermatology, 2017-03, Vol.137 (3), p.576-586

2017

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Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer

ACS medicinal chemistry letters, 2016-08, Vol.7 (8), p.785-790

2016

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Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells

Experimental hematology, 2013-11, Vol.41 (11), p.957-966

2013

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Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors

MedChemComm, 2013-07, Vol.4 (7), p.1085-1092

2013

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Disruption of the PI3K axis abrogates ionizing radiation‐induced cell death

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Conformational Restriction and Steric Hindrance in Medicinal Chemistry

Practice of Medicinal Chemistry, 2015, p.2-2

4th Edition, 2015

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Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitorsElectronic supplementary information (ESI) available: Experimental procedures and complete spectroscopic data for new compounds, protocols for cell and cell-free assays. See DOI: 10.1039/c3md00061c

2013-06

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Chapter 11 - Conformational Restriction and Steric Hindrance in Medicinal Chemistry

The Practice of Medicinal Chemistry, 2015, p.279-299

Fourth Edition, 2015

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46 - Resolution of CGD Related Colitis after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Chronic Granulomatous Disease—Early Results From the 6903 Study of the Primary Immune Deficiency Treatment Consortium (PIDTC)

Biology of blood and marrow transplantation, 2018-03, Vol.24 (3), p.S80-S81

2018

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Resolution of CGD Related Colitis after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Chronic Granulomatous Disease—Early Results From the 6903 Study of the Primary Immune Deficiency Treatment Consortium (PIDTC)

Biology of blood and marrow transplantation, 2018-03, Vol.24 (3), p.S80-S81

2018

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Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres

Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease

Deciphering of Mitochondrial Cardiolipin Oxidative Signaling in Cerebral Ischemia-Reperfusion

Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria

An Uncharged Oxetanyl Sulfoxide as a Covalent Modifier for Improving Aqueous Solubility

Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death

Enantioselective synthesis and selective functionalization of 4‐aminotetrahydroquinolines as novel GLP‐1 secretagogues

Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats

Pharmacological Mitigation of Tissue Damage during Brain Microdialysis

Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors

A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage

Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer

Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells

Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors

Disruption of the PI3K axis abrogates ionizing radiation‐induced cell death

Conformational Restriction and Steric Hindrance in Medicinal Chemistry

Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitorsElectronic supplementary information (ESI) available: Experimental procedures and complete spectroscopic data for new compounds, protocols for cell and cell-free assays. See DOI: 10.1039/c3md00061c

Chapter 11 - Conformational Restriction and Steric Hindrance in Medicinal Chemistry

46 - Resolution of CGD Related Colitis after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Chronic Granulomatous Disease—Early Results From the 6903 Study of the Primary Immune Deficiency Treatment Consortium (PIDTC)

Resolution of CGD Related Colitis after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Chronic Granulomatous Disease—Early Results From the 6903 Study of the Primary Immune Deficiency Treatment Consortium (PIDTC)

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