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Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres

Organic process research & development, 2012-01, Vol.16 (1), p.26-34

2012

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Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease

Cell reports (Cambridge), 2012-11, Vol.2 (5), p.1137-1142

2012

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Deciphering of Mitochondrial Cardiolipin Oxidative Signaling in Cerebral Ischemia-Reperfusion

Journal of cerebral blood flow and metabolism, 2015-02, Vol.35 (2), p.319-328

2015

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Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria

Organic & biomolecular chemistry, 2013-07, Vol.11 (25), p.4147-4153

2013

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An Uncharged Oxetanyl Sulfoxide as a Covalent Modifier for Improving Aqueous Solubility

ACS medicinal chemistry letters, 2014-08, Vol.5 (8), p.900-904

2014

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Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death

The Journal of pharmacology and experimental therapeutics, 2013-12, Vol.347 (3), p.669-680

2013

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Enantioselective synthesis and selective functionalization of 4‐aminotetrahydroquinolines as novel GLP‐1 secretagogues

Chirality (New York, N.Y.), 2022-03, Vol.34 (3), p.521-536

2022

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Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats

Journal of molecular and cellular cardiology, 2014-12, Vol.77, p.136-146

2014

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Pharmacological Mitigation of Tissue Damage during Brain Microdialysis

Analytical chemistry (Washington), 2013-09, Vol.85 (17), p.8173-8179

2013

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A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage

Journal of investigative dermatology, 2017-03, Vol.137 (3), p.576-586

2017

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Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors

Frontiers in oncology, 2014, Vol.4, p.24

2014

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Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer

ACS medicinal chemistry letters, 2016-08, Vol.7 (8), p.785-790

2016

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Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells

Experimental hematology, 2013-11, Vol.41 (11), p.957-966

2013

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Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors

MedChemComm, 2013-07, Vol.4 (7), p.1085-1092

2013

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Disruption of the PI3K axis abrogates ionizing radiation‐induced cell death

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Conformational Restriction and Steric Hindrance in Medicinal Chemistry

Practice of Medicinal Chemistry, 2015, p.2-2

4th Edition, 2015

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Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitorsElectronic supplementary information (ESI) available: Experimental procedures and complete spectroscopic data for new compounds, protocols for cell and cell-free assays. See DOI: 10.1039/c3md00061c

2013-06

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Chapter 11 - Conformational Restriction and Steric Hindrance in Medicinal Chemistry

The Practice of Medicinal Chemistry, 2015, p.279-299

Fourth Edition, 2015

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Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres

Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease

Deciphering of Mitochondrial Cardiolipin Oxidative Signaling in Cerebral Ischemia-Reperfusion

Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria

An Uncharged Oxetanyl Sulfoxide as a Covalent Modifier for Improving Aqueous Solubility

Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death

Enantioselective synthesis and selective functionalization of 4‐aminotetrahydroquinolines as novel GLP‐1 secretagogues

Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats

Pharmacological Mitigation of Tissue Damage during Brain Microdialysis

A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage

Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors

Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer

Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells

Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors

Disruption of the PI3K axis abrogates ionizing radiation‐induced cell death

Conformational Restriction and Steric Hindrance in Medicinal Chemistry

Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitorsElectronic supplementary information (ESI) available: Experimental procedures and complete spectroscopic data for new compounds, protocols for cell and cell-free assays. See DOI: 10.1039/c3md00061c

Chapter 11 - Conformational Restriction and Steric Hindrance in Medicinal Chemistry

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