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Drug repurposing and human parasitic protozoan diseases

International journal for parasitology -- drugs and drug resistance, 2014-08, Vol.4 (2), p.95-111

2014

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A Subset Screen of the Compounds Australia Scaffold Library Identifies 7-Acylaminodibenzoxazepinones as Potent and Selective Hits for Anti- Giardia Drug Discovery

Biomedicines, 2022-12, Vol.10 (12), p.3182

2022

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Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

International journal for parasitology -- drugs and drug resistance, 2017-04, Vol.7 (1), p.42-50

2017

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Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum

PloS one, 2012-02, Vol.7 (2), p.e31938-e31938

2012

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Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes

The Journal of infectious diseases, 2009-11, Vol.200 (10), p.1518-1521

2009

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Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2537-2542

2009

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An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation

International journal for parasitology -- drugs and drug resistance, 2020-12, Vol.14, p.249-256

2020

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Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

International journal for parasitology -- drugs and drug resistance, 2018-08, Vol.8 (2), p.189-193

2018

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Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis

International journal for parasitology -- drugs and drug resistance, 2023-12, Vol.23, p.54-62

2023

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The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

mBio, 2020-12, Vol.11 (6)

2020

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The Aminopeptidase Inhibitor CHR-2863 Is an Orally Bioavailable Inhibitor of Murine Malaria

Antimicrobial Agents and Chemotherapy, 2012-06, Vol.56 (6), p.3244-3249

2012

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Identification of Phosphinate Dipeptide Analog Inhibitors Directed against the Plasmodium falciparum M17 Leucine Aminopeptidase as Lead Antimalarial Compounds

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.6024-6031

2007

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An image-based Pathogen Box screen identifies new compounds with anti-Giardia activity and highlights the importance of assay choice in phenotypic drug discovery

International journal for parasitology -- drugs and drug resistance, 2020-04, Vol.12, p.60-67

2020

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Saquinavir Inhibits the Malaria Parasite's Chloroquine Resistance Transporter

Antimicrobial Agents and Chemotherapy, 2012-05, Vol.56 (5), p.2283-2289

2012

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A novel in vitro image-based assay identifies new drug leads for giardiasis

International journal for parasitology -- drugs and drug resistance, 2017-04, Vol.7 (1), p.83-89

2017

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Antiretrovirals as Antimalarial Agents

The Journal of infectious diseases, 2004-12, Vol.190 (11), p.1998-2000

2004

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Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea-Based HDAC Inhibitors

ChemMedChem, 2014-03, Vol.9 (3), p.665-670

2014

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Anti-Giardia Drug Discovery: Current Status and Gut Feelings

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13330-13354

2020

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Antimalarial Asexual Stage-Specific and Gametocytocidal Activities of HIV Protease Inhibitors

Antimicrobial Agents and Chemotherapy, 2010-03, Vol.54 (3), p.1334-1337

2010

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Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A-D

Marine drugs, 2015-09, Vol.13 (9), p.5784-5795

2015

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Identification of novel quinazoline derivatives as potent antiplasmodial agents

European journal of medicinal chemistry, 2019-01, Vol.161, p.277-291

2019

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The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment

PloS one, 2012-04, Vol.7 (4), p.e34399-e34399

2012

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The M18 Aspartyl Aminopeptidase of the Human Malaria Parasite Plasmodium falciparum

The Journal of biological chemistry, 2007-10, Vol.282 (42), p.30817-30826

2007

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HIV-1 Protease Inhibitors and Clinical Malaria: a Secondary Analysis of the AIDS Clinical Trials Group A5208 Study

Antimicrobial Agents and Chemotherapy, 2012-02, Vol.56 (2), p.995-1000

2012

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Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules

Antimicrobial agents and chemotherapy, 2014-07, Vol.58 (7), p.3666-3678

2014

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Drug repurposing and human parasitic protozoan diseases

A Subset Screen of the Compounds Australia Scaffold Library Identifies 7-Acylaminodibenzoxazepinones as Potent and Selective Hits for Anti- Giardia Drug Discovery

Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum

Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes

Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation

Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis

The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

The Aminopeptidase Inhibitor CHR-2863 Is an Orally Bioavailable Inhibitor of Murine Malaria

Identification of Phosphinate Dipeptide Analog Inhibitors Directed against the Plasmodium falciparum M17 Leucine Aminopeptidase as Lead Antimalarial Compounds

An image-based Pathogen Box screen identifies new compounds with anti-Giardia activity and highlights the importance of assay choice in phenotypic drug discovery

Saquinavir Inhibits the Malaria Parasite's Chloroquine Resistance Transporter

A novel in vitro image-based assay identifies new drug leads for giardiasis

Antiretrovirals as Antimalarial Agents

Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea-Based HDAC Inhibitors

Anti-Giardia Drug Discovery: Current Status and Gut Feelings

Antimalarial Asexual Stage-Specific and Gametocytocidal Activities of HIV Protease Inhibitors

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A-D

Identification of novel quinazoline derivatives as potent antiplasmodial agents

The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment

The M18 Aspartyl Aminopeptidase of the Human Malaria Parasite Plasmodium falciparum

HIV-1 Protease Inhibitors and Clinical Malaria: a Secondary Analysis of the AIDS Clinical Trials Group A5208 Study

Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules

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