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The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors

Current medicinal chemistry, 2004-11, Vol.11 (22), p.2911-2977

2004

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Inhibition of human leukocyte elastase (HLE) by N-substituted peptidyl trifluoromethyl ketones

Journal of medicinal chemistry, 1992-02, Vol.35 (4), p.641-662

1992

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Spiro indolinone beta-lactams, inhibitors of poliovirus and rhinovlrus 3C-proteinases

Tetrahedron letters, 1990, Vol.31 (50), p.7277-7280

1990

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The design, structure, and therapeutic application of matrix metalloproteinase inhibitors

Current medicinal chemistry, 2001-03, Vol.8 (4), p.425-474

2001

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Simultaneous determination of enantiomeric purity and erythro/ threo relationship in chiral 1,2-aminoalcohols by NMR using ( R)-(+)- t-butylphenylphosphinothioic acid

Tetrahedron: asymmetry, 1999-08, Vol.10 (17), p.3263-3266

1999

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elastase inhibitors containing conformationally restricted lactams as P3-P2 dipeptide replacements

Bioorganic & medicinal chemistry letters, 1993-04, Vol.3 (4), p.773-778

1993

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Angiotensin-converting enzyme inhibitors. New orally active antihypertensive (mercaptoalkanoyl)- and [(acylthio)alkanoyl]glycine derivatives

Journal of medicinal chemistry, 1985-01, Vol.28 (1), p.57-66

1985

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Inhibition of human leukocyte elastase by N-substituted peptides containing .alpha.,.alpha.-difluorostatone residues at P1

Journal of medicinal chemistry, 1992-12, Vol.35 (26), p.4795-4808

1992

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Angiotensin-converting enzyme inhibitors: new orally active 1,4-thiazepine-2,5-diones, 1,4-thiazine-2,5-diones, and 1,4-benzothiazepine-2,5-diones possessing antihypertensive activity

Journal of medicinal chemistry, 1986-05, Vol.29 (5), p.784-796

1986

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Angiotensin converting enzyme inhibitors. 9. Novel [[N-(1-carboxyl-3-phenylpropyl)amino]acyl]glycine derivatives with diuretic activity

Journal of medicinal chemistry, 1990-06, Vol.33 (6), p.1600-1606

1990

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Asymmetric synthesis of cis-(−)-(2 R4 S)-4-(phosphonomethyl)-2-piperidinecarboxylic acid, a potent NMDA receptor antagonist

Bioorganic & medicinal chemistry letters, 1996-04, Vol.6 (8), p.963-966

1996

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Therapeutic promises of leukocyte elastase and macrophage metalloelastase inhibitors for the treatment of pulmonary emphysema

Expert opinion on therapeutic patents, 1999-07, Vol.9 (7), p.869-895

1999

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Subsessiline: structure revision and synthesis

Journal of organic chemistry, 1979-02, Vol.44 (3), p.409-412

1979

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Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 1. Tricyclic pyridobenzo- and dipyridodiazepinones

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2231-2241

1991

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Inhibitors of Matrix Metalloproteinases: Design, Structure and Therapeutic Applications

Frontiers in Medicinal Chemistry - Online, 2004-01, Vol.1 (1), p.29-75

2004

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Novel Non-nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. 4. 2-Substituted Dipyridodiazepinones as Potent Inhibitors of Both Wild-Type and Cysteine-181 HIV-1 Reverse Transcriptase Enzymes

Journal of medicinal chemistry, 1995-11, Vol.38 (24), p.4830-4838

1995

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elastase inhibitors containing conformationally restricted lactams as P 3-P 2 dipeptide replacements

Bioorganic & medicinal chemistry letters, 1993-04, Vol.3 (4), p.773-778

1993

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Chapter 15. Matrix metalloproteinase inhibitors for treatment of cancer

Annual Reports in Medicinal Chemistry, 2000, Vol.35, p.167-176

2000

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Imidazo[1,2-a]piperazines as mechanistic inhibitors of serine proteinases

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (1), p.69-72

1991

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Angiotensin-converting enzyme inhibitors. 9.1 novel [[N-(1-carboxy-3-phenylpropyl)amino]acyl]glycine derivatives with diuretic activity

Journal of medicinal chemistry, 1990, Vol.33 (6), p.1600-1606

1990

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SYNTHESES OF N-CARBOXYMETHYL DIPEPTIDES via N-CARBOXY α-AMINO ACID ANHYDRIDES (NCA) INTERMEDIATES

Organic preparations and procedures international, 1988-04, Vol.20 (2), p.109-115

1988

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Alternative Methods for the Alkylation of Isoquinoline Reissert Compounds

Heterocycles, 1978, Vol.9 (5), p.653

1978

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Splendidine, a new oxoaporphine alkaloid from Abuta rufescens Aublet

Canadian journal of chemistry, 1979-01, Vol.57 (13), p.1642-1646

1979

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Splendidine, a new oxoaporphine alkaloid from Abutarufescens Aublet

Canadian journal of chemistry, 1979-07, Vol.57 (13), p.1642-1646

1979

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Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13

Journal of medicinal chemistry, 2009-06, Vol.52 (11), p.3523-3538

2009

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The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors

Inhibition of human leukocyte elastase (HLE) by N-substituted peptidyl trifluoromethyl ketones

Spiro indolinone beta-lactams, inhibitors of poliovirus and rhinovlrus 3C-proteinases

The design, structure, and therapeutic application of matrix metalloproteinase inhibitors

Simultaneous determination of enantiomeric purity and erythro/ threo relationship in chiral 1,2-aminoalcohols by NMR using ( R)-(+)- t-butylphenylphosphinothioic acid

elastase inhibitors containing conformationally restricted lactams as P3-P2 dipeptide replacements

Angiotensin-converting enzyme inhibitors. New orally active antihypertensive (mercaptoalkanoyl)- and [(acylthio)alkanoyl]glycine derivatives

Inhibition of human leukocyte elastase by N-substituted peptides containing .alpha.,.alpha.-difluorostatone residues at P1

Angiotensin-converting enzyme inhibitors: new orally active 1,4-thiazepine-2,5-diones, 1,4-thiazine-2,5-diones, and 1,4-benzothiazepine-2,5-diones possessing antihypertensive activity

Angiotensin converting enzyme inhibitors. 9. Novel [[N-(1-carboxyl-3-phenylpropyl)amino]acyl]glycine derivatives with diuretic activity

Asymmetric synthesis of cis-(−)-(2 R4 S)-4-(phosphonomethyl)-2-piperidinecarboxylic acid, a potent NMDA receptor antagonist

Therapeutic promises of leukocyte elastase and macrophage metalloelastase inhibitors for the treatment of pulmonary emphysema

Subsessiline: structure revision and synthesis

Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 1. Tricyclic pyridobenzo- and dipyridodiazepinones

Inhibitors of Matrix Metalloproteinases: Design, Structure and Therapeutic Applications

Novel Non-nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. 4. 2-Substituted Dipyridodiazepinones as Potent Inhibitors of Both Wild-Type and Cysteine-181 HIV-1 Reverse Transcriptase Enzymes

elastase inhibitors containing conformationally restricted lactams as P 3-P 2 dipeptide replacements

Chapter 15. Matrix metalloproteinase inhibitors for treatment of cancer

Imidazo[1,2-a]piperazines as mechanistic inhibitors of serine proteinases

Angiotensin-converting enzyme inhibitors. 9.1 novel [[N-(1-carboxy-3-phenylpropyl)amino]acyl]glycine derivatives with diuretic activity

SYNTHESES OF N-CARBOXYMETHYL DIPEPTIDES via N-CARBOXY α-AMINO ACID ANHYDRIDES (NCA) INTERMEDIATES

Alternative Methods for the Alkylation of Isoquinoline Reissert Compounds

Splendidine, a new oxoaporphine alkaloid from Abuta rufescens Aublet

Splendidine, a new oxoaporphine alkaloid from Abutarufescens Aublet

Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13

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