UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

The different autophagy degradation pathways and neurodegeneration

Neuron (Cambridge, Mass.), 2022-03, Vol.110 (6), p.935-966

2022

Volltextzugriff (PDF)

Systematic Investigation of the Permeability of Androgen Receptor PROTACs

ACS medicinal chemistry letters, 2020-08, Vol.11 (8), p.1539-1547

2020

Volltextzugriff (PDF)

Asymmetric epoxidation of electron-deficient olefins

Chemical communications (Cambridge, England), 2000-01 (14), p.1215-1225

2000

Volltextzugriff (PDF)

The Asymmetric Aza-silyl-Prins Reaction: Synthesis of Enantiopure Piperidines

Organic letters, 2019-01, Vol.21 (2), p.350-355

2019

Volltextzugriff (PDF)

Disease phenotypic screening in neuron-glia cocultures identifies blockers of inflammatory neurodegeneration

iScience, 2024-04, Vol.27 (4), p.109454-109454, Article 109454

2024

Volltextzugriff (PDF)

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

Neuron (Cambridge, Mass.), 2017-03, Vol.93 (5), p.1015-1034

2017

Volltextzugriff (PDF)

Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

Nature reviews. Drug discovery, 2016-08, Vol.15 (8), p.533-550

2016

Volltextzugriff (PDF)

Optimization of Sphingosine-1-phosphate‑1 Receptor Agonists: Effects of Acidic, Basic, and Zwitterionic Chemotypes on Pharmacokinetic and Pharmacodynamic Profiles

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10424-10442

2014

Volltextzugriff (PDF)

Therapeutic inhibition of ferroptosis in neurodegenerative disease

Trends in pharmacological sciences (Regular ed.), 2023-10, Vol.44 (10), p.674-688

2023

Volltextzugriff (PDF)

Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia

Nature neuroscience, 2024-09

2024

Volltextzugriff (PDF)

The toolbox is open, but who should pay for the job? Establishing industry-funded grant programmes for early-stage drug research could help address the dual challenges of declining government funding and optimizing the effectiveness of industry investment

Nature reviews. Drug discovery, 2014-07, Vol.13 (7), p.479

2014

Volltextzugriff (PDF)

Development of Selective Phosphatidylinositol 5‑Phosphate 4‑Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.3359-3370

2022

Volltextzugriff (PDF)

Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents

Journal of medicinal chemistry, 2024-09, Vol.67 (17), p.15521-15536

2024

Volltextzugriff (PDF)

The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules

Journal of medicinal chemistry, 2023-01, Vol.66 (1), p.804-821

2023

Volltextzugriff (PDF)

p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003

Acta neuropathologica, 2024-06, Vol.147 (1), p.7, Article 7

2024

Volltextzugriff (PDF)

The toolbox is open, but who should pay for the job?

Nature reviews. Drug discovery, 2014-07, Vol.13 (7), p.479-480

2014

Volltextzugriff (PDF)

Development of the Juliá−Colonna Asymmetric Epoxidation Reaction: Part 1. Preparation and Activation of the Polyleucine Catalyst

Organic process research & development, 2003-07, Vol.7 (4), p.509-513

2003

Volltextzugriff (PDF)

Total synthesis of (-)-nakadomarin A

Chemical communications (Cambridge, England), 2011-09, Vol.47 (36), p.10037-10039

2011

Volltextzugriff (PDF)

New procedures for the Juliá–Colonna asymmetric epoxidation: synthesis of (+)-clausenamide

Chemical communications (Cambridge, England), 1998 (10), p.1159-1160

1998

Volltextzugriff (PDF)

RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia-an international Delphi consensus

Alzheimer's research & therapy, 2022-11, Vol.14 (1), p.169-169, Article 169

2022

Volltextzugriff (PDF)

Identification of ARUK2002821 as an isoform-selective PI5P4Kα inhibitor

RSC medicinal chemistry, 2023-05, Vol.14 (5), p.934-946

2023

Volltextzugriff (PDF)

The rational design of ARUK2007145, a dual inhibitor of the α and γ isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)

RSC medicinal chemistry, 2023-10, Vol.14 (1), p.235-247

2023

Volltextzugriff (PDF)

Engineering Archeal Surrogate Systems for the Development of Protein–Protein Interaction Inhibitors against Human RAD51

Journal of molecular biology, 2016-11, Vol.428 (23), p.4589-4607

2016

Volltextzugriff (PDF)

Rapid access to CF3-containing heterocycles

Tetrahedron letters, 2008-01, Vol.49 (5), p.827-831

2008

Volltextzugriff (PDF)

1 – 25 von 323

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(274)
Mit Volltextzugriff
(271)

Publikationsform

3 weitere anzeigen...

Weniger anzeigen...

Sprache

Englisch
(320)
Japanisch
(1)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

Menü

Weitere Dienste

Einstellungen

The different autophagy degradation pathways and neurodegeneration

A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death

Systematic Investigation of the Permeability of Androgen Receptor PROTACs

Asymmetric epoxidation of electron-deficient olefins

The Asymmetric Aza-silyl-Prins Reaction: Synthesis of Enantiopure Piperidines

Disease phenotypic screening in neuron-glia cocultures identifies blockers of inflammatory neurodegeneration

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

Optimization of Sphingosine-1-phosphate‑1 Receptor Agonists: Effects of Acidic, Basic, and Zwitterionic Chemotypes on Pharmacokinetic and Pharmacodynamic Profiles

Therapeutic inhibition of ferroptosis in neurodegenerative disease

Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia

The toolbox is open, but who should pay for the job? Establishing industry-funded grant programmes for early-stage drug research could help address the dual challenges of declining government funding and optimizing the effectiveness of industry investment

Development of Selective Phosphatidylinositol 5‑Phosphate 4‑Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode

Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents

The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules

p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003

The toolbox is open, but who should pay for the job?

Development of the Juliá−Colonna Asymmetric Epoxidation Reaction: Part 1. Preparation and Activation of the Polyleucine Catalyst

Total synthesis of (-)-nakadomarin A

New procedures for the Juliá–Colonna asymmetric epoxidation: synthesis of (+)-clausenamide

RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia-an international Delphi consensus

Identification of ARUK2002821 as an isoform-selective PI5P4Kα inhibitor

The rational design of ARUK2007145, a dual inhibitor of the α and γ isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)

Engineering Archeal Surrogate Systems for the Development of Protein–Protein Interaction Inhibitors against Human RAD51

Rapid access to CF3-containing heterocycles

Suchergebnisse filtern