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Problems in using isolated and cultured hepatocytes for xenobiotic metabolism/metabolism-based toxicity testing—Solutions?

Toxicology in Vitro, 1994-06, Vol.8 (3), p.491-504

Skett, P.

1994

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Inhibition of metallo-beta-lactamases by a series of mercaptoacetic acid thiol ester derivatives

Antimicrobial Agents and Chemotherapy, 1997-01, Vol.41 (1), p.135-140

1997

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Acta Biologica et Medica Germanica

2022

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SB-203207 and SB-203208, Two Novel Isoleucyl tRNA Synthetase Inhibitors from a Streptomyces sp: II. Structure Determination

The Journal of Antibiotics, 2000/04/25, Vol.53(4), pp.364-372

2000

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In vitro effect of fenugreek extracts on intestinal sodium-dependent glucose uptake and hepatic glycogen phosphorylase A

International journal of experimental diabetes research, 2001, Vol.2 (2), p.91-99

2001

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Maintenance of steroid metabolism and hormone responsiveness in cryopreserved dog, monkey and human hepatocytes

Chemico-biological interactions, 1999-06, Vol.121 (1), p.65-76

1999

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Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

Biochemical journal, 1992-01, Vol.281 (2), p.359-368

1992

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Sex steroid induced changes in hepatic enzymes

Annual review of physiology, 1983-01, Vol.45 (1), p.51-60

1983

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Changes in adenosine sensitivity in the hippocampus of rats with streptozotocin‐induced diabetes

British journal of pharmacology, 1992-04, Vol.105 (4), p.1004-1008

1992

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The Practical Applicability of Hepatocyte Cultures in Routine Testing: The Report and Recommendations of ECVAM Workshop 1

Alternatives to laboratory animals, 1994-07, Vol.22 (4), p.231-241

1994

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Role of hormones in the control of mixed-function oxidases

Biochemical Society transactions, 1990-02, Vol.18 (1), p.24-26

Skett, P

1990

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Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel

Chemico-biological interactions, 1999-06, Vol.121 (1), p.117-123

1999

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Sex-dependent effect of streptozotocin-induced diabetes mellitus on hepatic steroid metabolism in the rat

Acta endocrinologica (Copenhagen), 1986-02, Vol.111 (2), p.217-221

Skett, P

1986

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Report on the International Workshop on the Use of Human In Vitro Liver Preparations to Study Drug Metabolism in Drug Development

Biochemical pharmacology, 1995, Vol.50 (2), p.280-285

1995

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The time course of the effect of hypophysectomy and oestrogen treatment on the hepatic metabolism of androst-4-ene-3,17-dione in male and female rats

Biochemical journal, 1978-09, Vol.174 (3), p.753-760

Skett, P

1978

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Biochemical basis of sex differences in drug metabolism

Pharmacology & therapeutics (Oxford), 1988, Vol.38 (3), p.269-304

Skett, Paul

1988

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Maintenance of liver-specific function in cultured hepatocytes in different media

Biochemical Society transactions, 1993-02, Vol.21 (1), p.70S-70S

1993

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Cryopreservation of hepatocytes: a review of current methods for banking

Cell and tissue banking, 2003, Vol.4 (1), p.3-15

2003

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The role of microsomal phospholipids and their fatty acid composition in the control of hepatic metabolism of lignocaine

British journal of pharmacology, 1989-12, Vol.98 (4), p.1399-1405

1989

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Mechanism of action of cyclic AMP in altering steroid metabolism in permeabilized rat hepatocytes

Journal of molecular endocrinology, 1988-11, Vol.1 (3), p.165-170

1988

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Effect of phorbol esters and diacylglycerol on steroid metabolism in isolated rat hepatocytes

Journal of endocrinology, 1988-07, Vol.118 (1), p.19-23

1988

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Endocrine regulation of the metabolism of 1-naphthol in the rat

The Journal of pharmacology and experimental therapeutics, 1987-07, Vol.242 (1), p.344

1987

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Time course of the effect of streptozotocin on serum concentration of glucose and triglycerides and on hepatic drug metabolism in the male rat

Acta endocrinologica (Copenhagen), 1986-06, Vol.112 (2), p.300-304

1986

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The design and operation of a novel device for collecting fractions from TLC plates for biological and spectroscopic analysis

JPC. Journal of planar chromatography, modern TLC, 1997-07, Vol.10 (4), p.263-266

SKETT, P

1997

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Report on the International Workshop on the Use of Human In Vitro Liver Preparations to Study Drug Metabolism in Drug Development : held at Utrecht, The Netherlands, 6–8 September 1994

Biochemical pharmacology, 1995-07, Vol.50 (2), p.280-285

1995

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Problems in using isolated and cultured hepatocytes for xenobiotic metabolism/metabolism-based toxicity testing—Solutions?

Inhibition of metallo-beta-lactamases by a series of mercaptoacetic acid thiol ester derivatives

Acta Biologica et Medica Germanica

SB-203207 and SB-203208, Two Novel Isoleucyl tRNA Synthetase Inhibitors from a Streptomyces sp: II. Structure Determination

In vitro effect of fenugreek extracts on intestinal sodium-dependent glucose uptake and hepatic glycogen phosphorylase A

Maintenance of steroid metabolism and hormone responsiveness in cryopreserved dog, monkey and human hepatocytes

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

Sex steroid induced changes in hepatic enzymes

Changes in adenosine sensitivity in the hippocampus of rats with streptozotocin‐induced diabetes

The Practical Applicability of Hepatocyte Cultures in Routine Testing: The Report and Recommendations of ECVAM Workshop 1

Role of hormones in the control of mixed-function oxidases

Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel

Sex-dependent effect of streptozotocin-induced diabetes mellitus on hepatic steroid metabolism in the rat

Report on the International Workshop on the Use of Human In Vitro Liver Preparations to Study Drug Metabolism in Drug Development

The time course of the effect of hypophysectomy and oestrogen treatment on the hepatic metabolism of androst-4-ene-3,17-dione in male and female rats

Biochemical basis of sex differences in drug metabolism

Maintenance of liver-specific function in cultured hepatocytes in different media

Cryopreservation of hepatocytes: a review of current methods for banking

The role of microsomal phospholipids and their fatty acid composition in the control of hepatic metabolism of lignocaine

Mechanism of action of cyclic AMP in altering steroid metabolism in permeabilized rat hepatocytes

Effect of phorbol esters and diacylglycerol on steroid metabolism in isolated rat hepatocytes

Endocrine regulation of the metabolism of 1-naphthol in the rat

Time course of the effect of streptozotocin on serum concentration of glucose and triglycerides and on hepatic drug metabolism in the male rat

The design and operation of a novel device for collecting fractions from TLC plates for biological and spectroscopic analysis

Report on the International Workshop on the Use of Human In Vitro Liver Preparations to Study Drug Metabolism in Drug Development : held at Utrecht, The Netherlands, 6–8 September 1994

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