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A Tetrachloro Polyketide Hexahydro-1H-isoindolone, Muironolide A, from the Marine Sponge Phorbas sp. Natural Products at the Nanomole Scale

Journal of the American Chemical Society, 2009-06, Vol.131 (22), p.7552-7553

2009

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Synthesis and Antifungal Activity of (−)-(Z)-Dysidazirine

Organic letters, 2008-11, Vol.10 (22), p.5269-5271

2008

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Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (6), p.2029-2032

2010

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Phorbasides A−E, Cytotoxic Chlorocyclopropane Macrolide Glycosides from the Marine Sponge Phorbas sp. CD Determination of C-Methyl Sugar Configurations

Journal of organic chemistry, 2008-05, Vol.73 (10), p.3699-3706

2008

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Ene-yne Tetrahydrofurans from the Sponge Xestospongia muta. Exploiting a Weak CD Effect for Assignment of Configuration

Organic letters, 2007-05, Vol.9 (10), p.1975-1978

2007

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Chlorocyclopropane Macrolides from the Marine Sponge Phorbas sp. Assignment of the Configurations of Phorbasides A and B by Quantitative CD

Journal of the American Chemical Society, 2007-04, Vol.129 (14), p.4150-4151

2007

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Synchronous bond molecular dynamics of conjugated chlorocyclopropyl alk‐yn‐enes revealed by ECD and UV–vis

Chirality (New York, N.Y.), 2020-08, Vol.32 (8), p.1037-1044

2020

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Total Synthesis of Enigmazole A from Cinachyrella enigmatica. Bidirectional Bond Constructions with an Ambident 2,4-Disubstituted Oxazole Synthon

Journal of the American Chemical Society, 2010-08, Vol.132 (30), p.10286-10292

2010

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Transannular Diels–Alder/1,3-Dipolar Cycloaddition Cascade of 1,3,4-Oxadiazoles: Total Synthesis of a Unique Set of Vinblastine Analogues

Organic letters, 2013-10, Vol.15 (20), p.5306-5309

2013

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Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7773-7816

2020

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Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.6329-6357

2021

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Long-Chain 2H-Azirines with Heterogeneous Terminal Halogenation from the Marine Sponge Dysidea fragilis

Journal of organic chemistry, 2008-04, Vol.73 (7), p.2592-2597

2008

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Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3309-3324

2018

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Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3325-3349

2018

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Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity

Chemical science (Cambridge), 2017-02, Vol.8 (2), p.1560-1569

2017

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Addition of Cl2C: to (−)-O-Menthyl Acrylate under Sonication−Phase-Transfer Catalysis. Efficient Synthesis of (+)- and (−)-(2-Chlorocyclopropyl)methanol

Journal of organic chemistry, 2005-05, Vol.70 (10), p.4162-4165

2005

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Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics

ACS infectious diseases, 2018-03, Vol.4 (3), p.391-402

2018

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Rhizochalins C and D from the Sponge Rhizochalina incrustata. A Rare threo-Sphingolipid and a Facile Method for Determination of the Carbonyl Position in α,ω-Bifunctionalized Ketosphingolipids

Journal of natural products (Washington, D.C.), 2007-12, Vol.70 (12), p.1991-1998

2007

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Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activityElectronic supplementary information (ESI) available: Full experimental details and copies of 1H and 13C NMR spectra are provided. CCDC 1475225-1475228. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04146a

2017-01

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Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity† †Electronic supplementary information (ESI) available: Full experimental details and copies of 1H and 13C NMR spectra are provided. CCDC 1475225–1475228. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04146a Click here for additional data file. Click here for additional data file

Chemical science (Cambridge), 2016-11, Vol.8 (2), p.1560-1569

2016

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Long-Chain 2 H -Azirines with Heterogeneous Terminal Halogenation from the Marine Sponge Dysidea fragilis

Journal of organic chemistry, 2008-04, Vol.73 (7), p.2592-2597

2008

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Synthesis and chain-dependent antifungal activity of long-chain 2 H-azirine-carboxylate esters related to dysidazirine

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (6), p.2029-2032

2010

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Synthesis and Anti-fungal Activity of (−)-(Z)-Dysidazirine

Organic letters, 2008-10, Vol.10 (22), p.5269-5271

2008

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A Tetrachloro Polyketide Hexahydro-1 H -isoindolone, Muironolide A, from the Marine Sponge Phorbas sp. Natural Products at the Nanomole Scale

Journal of the American Chemical Society, 2009-06, Vol.131 (22), p.7552-7553

2009

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Addition of Cl 2 C: to (−)- O -Menthyl Acrylate under Sonication−Phase-Transfer Catalysis. Efficient Synthesis of (+)- and (−)-(2-Chlorocyclopropyl)methanol

Journal of organic chemistry, 2005-05, Vol.70 (10), p.4162-4165

2005

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A Tetrachloro Polyketide Hexahydro-1H-isoindolone, Muironolide A, from the Marine Sponge Phorbas sp. Natural Products at the Nanomole Scale

Synthesis and Antifungal Activity of (−)-(Z)-Dysidazirine

Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine

Phorbasides A−E, Cytotoxic Chlorocyclopropane Macrolide Glycosides from the Marine Sponge Phorbas sp. CD Determination of C-Methyl Sugar Configurations

Ene-yne Tetrahydrofurans from the Sponge Xestospongia muta. Exploiting a Weak CD Effect for Assignment of Configuration

Chlorocyclopropane Macrolides from the Marine Sponge Phorbas sp. Assignment of the Configurations of Phorbasides A and B by Quantitative CD

Synchronous bond molecular dynamics of conjugated chlorocyclopropyl alk‐yn‐enes revealed by ECD and UV–vis

Total Synthesis of Enigmazole A from Cinachyrella enigmatica. Bidirectional Bond Constructions with an Ambident 2,4-Disubstituted Oxazole Synthon

Transannular Diels–Alder/1,3-Dipolar Cycloaddition Cascade of 1,3,4-Oxadiazoles: Total Synthesis of a Unique Set of Vinblastine Analogues

Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria

Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria

Long-Chain 2H-Azirines with Heterogeneous Terminal Halogenation from the Marine Sponge Dysidea fragilis

Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria

Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity

Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity

Addition of Cl2C: to (−)-O-Menthyl Acrylate under Sonication−Phase-Transfer Catalysis. Efficient Synthesis of (+)- and (−)-(2-Chlorocyclopropyl)methanol

Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics

Rhizochalins C and D from the Sponge Rhizochalina incrustata. A Rare threo-Sphingolipid and a Facile Method for Determination of the Carbonyl Position in α,ω-Bifunctionalized Ketosphingolipids

Long-Chain 2 H -Azirines with Heterogeneous Terminal Halogenation from the Marine Sponge Dysidea fragilis

Synthesis and chain-dependent antifungal activity of long-chain 2 H-azirine-carboxylate esters related to dysidazirine

Synthesis and Anti-fungal Activity of (−)-(Z)-Dysidazirine

A Tetrachloro Polyketide Hexahydro-1 H -isoindolone, Muironolide A, from the Marine Sponge Phorbas sp. Natural Products at the Nanomole Scale

Addition of Cl 2 C: to (−)- O -Menthyl Acrylate under Sonication−Phase-Transfer Catalysis. Efficient Synthesis of (+)- and (−)-(2-Chlorocyclopropyl)methanol

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