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Anthracycline resistance mediated by reductive metabolism in cancer cells: The role of aldo-keto reductase 1C3

Toxicology and applied pharmacology, 2014-08, Vol.278 (3), p.238-248

2014

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Silencing of E-cadherin expression leads to increased chemosensitivity to irinotecan and oxaliplatin in colorectal cancer cell lines

Human & experimental toxicology, 2021-12, Vol.40 (12), p.2063-2073

2021

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Expression of STAT3 and hypoxia markers in long-term surviving malignant glioma patients

BMC cancer, 2024-04, Vol.24 (1), p.509-509, Article 509

2024

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The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines

Molecules (Basel, Switzerland), 2017-06, Vol.22 (6), p.1021

2017

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BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS

Biomedicine & pharmacotherapy, 2023-11, Vol.167, p.115490-115490, Article 115490

2023

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Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo

International journal of molecular sciences, 2021-11, Vol.22 (21), p.11936

2021

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The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells

Molecules (Basel, Switzerland), 2015-08, Vol.20 (8), p.15343-15358

2015

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Frentizole derivatives with mTOR inhibiting and senomorphic properties

Biomedicine & pharmacotherapy, 2023-11, Vol.167, p.115600-115600, Article 115600

2023

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Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

Frontiers in aging neuroscience, 2022-12, Vol.14, p.1048260-1048260

2022

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Role of N-Cadherin in Epithelial-to-Mesenchymal Transition and Chemosensitivity of Colon Carcinoma Cells

Cancers, 2022-10, Vol.14 (20), p.5146

2022

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The Evaluation of Glioblastoma Cell Dissociation and Its Influence on Its Behavior

International journal of molecular sciences, 2019-09, Vol.20 (18), p.4630

2019

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Physiological and biochemical responses of Brassica napus L. cultivars exposed to Cd stress

Plant, soil and environment, 2022-01, Vol.68 (9), p.431-440

2022

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Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme

Cancers, 2020-03, Vol.12 (4), p.813

2020

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Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes

Chemico-biological interactions, 2017-10, Vol.276, p.121-126

2017

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Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.437-449

2021

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Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions

Frontiers in pharmacology, 2019-05, Vol.10, p.600-600

2019

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Hydroxysteroid dehydrogenases (HSDs) in bacteria – A bioinformatic perspective

The Journal of steroid biochemistry and molecular biology, 2012-03, Vol.129 (1-2), p.31-46

2012

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Enzyme stereospecificity as a powerful tool in searching for new enzymes

Current drug metabolism, 2010-07, Vol.11 (6), p.547-559

2010

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Pharmacokinetic interactions of breast cancer chemotherapeutics with human doxorubicin reductases

Biochemical pharmacology, 2015-08, Vol.96 (3), p.168-178

2015

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7-Amino-3-phenyl-2-methyl-pyrazolopyrimidine derivatives inhibit human rhinovirus replication

European journal of medicinal chemistry, 2024-10, Vol.276, p.116690, Article 116690

2024

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Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter

Toxicology and applied pharmacology, 2022-01, Vol.434, p.115823, Article 115823

2022

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Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents

Archives of toxicology, 2024-09, Vol.98 (9), p.2937-2952

2024

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Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10753-10766

2018

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The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice

Biomedicine & pharmacotherapy, 2017-11, Vol.95, p.828-836

2017

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Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation

European journal of medicinal chemistry, 2023-10, Vol.258, p.115593-115593, Article 115593

2023

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Anthracycline resistance mediated by reductive metabolism in cancer cells: The role of aldo-keto reductase 1C3

Silencing of E-cadherin expression leads to increased chemosensitivity to irinotecan and oxaliplatin in colorectal cancer cell lines

Expression of STAT3 and hypoxia markers in long-term surviving malignant glioma patients

The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines

BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS

Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo

The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells

Frentizole derivatives with mTOR inhibiting and senomorphic properties

Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

Role of N-Cadherin in Epithelial-to-Mesenchymal Transition and Chemosensitivity of Colon Carcinoma Cells

The Evaluation of Glioblastoma Cell Dissociation and Its Influence on Its Behavior

Physiological and biochemical responses of Brassica napus L. cultivars exposed to Cd stress

Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme

Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes

Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates

Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions

Hydroxysteroid dehydrogenases (HSDs) in bacteria – A bioinformatic perspective

Enzyme stereospecificity as a powerful tool in searching for new enzymes

Pharmacokinetic interactions of breast cancer chemotherapeutics with human doxorubicin reductases

7-Amino-3-phenyl-2-methyl-pyrazolopyrimidine derivatives inhibit human rhinovirus replication

Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter

Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents

Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents

The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice

Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation

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