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Whole-genome sequencing of recurrent neuroblastoma reveals somatic mutations that affect key players in cancer progression and telomere maintenance

Scientific reports, 2020-12, Vol.10 (1), p.22432-22432, Article 22432

2020

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Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus

Biochemistry (Easton), 2022-01, Vol.61 (2), p.92-106

2022

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High-Risk Neuroblastoma Tumors with 11q-Deletion Display a Poor Prognostic, Chromosome Instability Phenotype with Later Onset

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4323-4328

2010

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RNRdb, a curated database of the universal enzyme family ribonucleotide reductase, reveals a high level of misannotation in sequences deposited to Genbank

BMC genomics, 2009-12, Vol.10 (1), p.589-589, Article 589

2009

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A metagenomics transect into the deepest point of the Baltic Sea reveals clear stratification of microbial functional capacities

PloS one, 2013-09, Vol.8 (9), p.e74983

2013

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A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site

The Journal of biological chemistry, 2020-11, Vol.295 (46), p.15576-15587

2020

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Low Frequency ALK Hotspots Mutations In Neuroblastoma Tumours Detected By Ultra-deep Sequencing: Implications For ALK Inhibitor Treatment

Scientific reports, 2019-02, Vol.9 (1), p.2199-2199, Article 2199

2019

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NrdI Essentiality for Class Ib Ribonucleotide Reduction in Streptococcus pyogenes

Journal of Bacteriology, 2008-07, Vol.190 (14), p.4849-4858

2008

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Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding

eLife, 2024-07, Vol.12

2024

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Ribonucleotide reduction - horizontal transfer of a required function spans all three domains

BMC evolutionary biology, 2010-12, Vol.10, p.383

2010

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Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones

Structure (London), 2016-06, Vol.24 (6), p.906-917

2016

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Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors

BMC genomics, 2011-09, Vol.12 (1), p.443-443, Article 443

2011

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NrdR Controls Differential Expression of the Escherichia coli Ribonucleotide Reductase Genes

Journal of Bacteriology, 2007-07, Vol.189 (14), p.5012-5021

2007

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Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma

BMC cancer, 2011-02, Vol.11 (1), p.66-66, Article 66

2011

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Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy

Frontiers in molecular biosciences, 2021-07, Vol.8, p.713608-713608

2021

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Diversity in Overall Activity Regulation of Ribonucleotide Reductase

The Journal of biological chemistry, 2015-07, Vol.290 (28), p.17339-17348

2015

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Biochemical Characterization of the Split Class II Ribonucleotide Reductase from Pseudomonas aeruginosa

PloS one, 2015-07, Vol.10 (7), p.e0134293-e0134293

2015

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High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene

BMC genomics, 2008-07, Vol.9 (1), p.353-353, Article 353

2008

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Bacillus anthracis Thioredoxin Systems, Characterization and Role as Electron Donors for Ribonucleotide Reductase

The Journal of biological chemistry, 2012-11, Vol.287 (47), p.39686-39697

2012

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DNA building blocks: keeping control of manufacture

Critical reviews in biochemistry and molecular biology, 2012-01, Vol.47 (1), p.50-63

2012

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A Glycyl Radical Site in the Crystal Structure of a Class III Ribonucleotide Reductase

Science (American Association for the Advancement of Science), 1999-03, Vol.283 (5407), p.1499-1504

1999

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Smart polymeric coatings for damage visualization in substrate materials

Journal of intelligent material systems and structures, 2012-08, Vol.23 (12), p.1371-1377

2012

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A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases

Nature communications, 2022-05, Vol.13 (1), p.2700-2700, Article 2700

2022

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Self-Splicing of the Bacteriophage T4 Group I Introns Requires Efficient Translation of the Pre-mRNA In Vivo and Correlates with the Growth State of the Infected Bacterium

Journal of Bacteriology, 2007-02, Vol.189 (3), p.980-990

2007

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NrdH-Redoxin Protein Mediates High Enzyme Activity in Manganese-reconstituted Ribonucleotide Reductase from Bacillus anthracis

The Journal of biological chemistry, 2011-09, Vol.286 (38), p.33053-33060

2011

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Whole-genome sequencing of recurrent neuroblastoma reveals somatic mutations that affect key players in cancer progression and telomere maintenance

Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus

High-Risk Neuroblastoma Tumors with 11q-Deletion Display a Poor Prognostic, Chromosome Instability Phenotype with Later Onset

RNRdb, a curated database of the universal enzyme family ribonucleotide reductase, reveals a high level of misannotation in sequences deposited to Genbank

A metagenomics transect into the deepest point of the Baltic Sea reveals clear stratification of microbial functional capacities

A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site

Low Frequency ALK Hotspots Mutations In Neuroblastoma Tumours Detected By Ultra-deep Sequencing: Implications For ALK Inhibitor Treatment

NrdI Essentiality for Class Ib Ribonucleotide Reduction in Streptococcus pyogenes

Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding

Ribonucleotide reduction - horizontal transfer of a required function spans all three domains

Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones

Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors

NrdR Controls Differential Expression of the Escherichia coli Ribonucleotide Reductase Genes

Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma

Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy

Diversity in Overall Activity Regulation of Ribonucleotide Reductase

Biochemical Characterization of the Split Class II Ribonucleotide Reductase from Pseudomonas aeruginosa

High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene

Bacillus anthracis Thioredoxin Systems, Characterization and Role as Electron Donors for Ribonucleotide Reductase

DNA building blocks: keeping control of manufacture

A Glycyl Radical Site in the Crystal Structure of a Class III Ribonucleotide Reductase

Smart polymeric coatings for damage visualization in substrate materials

A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases

Self-Splicing of the Bacteriophage T4 Group I Introns Requires Efficient Translation of the Pre-mRNA In Vivo and Correlates with the Growth State of the Infected Bacterium

NrdH-Redoxin Protein Mediates High Enzyme Activity in Manganese-reconstituted Ribonucleotide Reductase from Bacillus anthracis

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