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Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical Relevance

Drug metabolism and disposition, 2018-09, Vol.46 (9), p.1285-1303

2018

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Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk Assessment

Drug metabolism and disposition, 2021-01, Vol.49 (1), p.94-110

2021

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Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control

Drug metabolism and disposition, 2017-10, Vol.45 (10), p.1049-1059

2017

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Celecoxib is a substrate of CYP2D6: Impact on celecoxib metabolism in individuals with CYP2C93 variants

Drug metabolism and pharmacokinetics, 2018-10, Vol.33 (5), p.219-227

2018

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Impact of Probe Substrate Selection on Cytochrome P450 Reaction Phenotyping Using the Relative Activity Factor

Drug metabolism and disposition, 2017-02, Vol.45 (2), p.183-189

2017

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Pharmacokinetic/pharmacodynamic drug–drug interactions of avatrombopag when coadministered with dual or selective CYP2C9 and CYP3A interacting drugs

British journal of clinical pharmacology, 2018-05, Vol.84 (5), p.952-960

2018

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First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE 2 -receptor E-type 4 (EP4), in patients with advanced cancers

Journal for immunotherapy of cancer, 2020-06, Vol.8 (1), p.e000222

2020

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Metabolic disposition of H3B-8800, an orally available small-molecule splicing modulator, in rats, monkeys, and humans

Xenobiotica, 2020-09, Vol.50 (9), p.1101-1114

2020

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Impact of probe substrates selection on the outcome of CYP reaction phenotyping study

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S50-S51

2017

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Stereoselective metabolism of pyrido[3,2-D]pyrimidine-containing compounds by aldehyde oxidase

Drug metabolism and pharmacokinetics, 2018-01, Vol.33 (1), p.S83-S83

2018

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Recommendations for in vitro CYP3A4 mRNA data analysis for drug-drug interaction risk assessment from the IQ Induction working group

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S44-S44

2019

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Considerations from the IQ induction working group in response to drug–drug interaction guidances from regulatory agencies

Drug metabolism and pharmacokinetics, 2018-01, Vol.33 (1), p.S52-S52

2018

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First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers

Journal for immunotherapy of cancer, 2020-06, Vol.8 (1)

2020

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Comprehensive Defensin Assay for Saliva

Analytical chemistry (Washington), 2009-01, Vol.81 (2), p.557-566

2009

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eFIP: a tool for mining functional impact of phosphorylation from literature

Methods in molecular biology (Clifton, N.J.), 2011, Vol.694, p.63

2011

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Initial uptake, time to treatment, and real-world effectiveness of all-oral direct-acting antivirals for hepatitis C virus infection in the United States: A retrospective cohort analysis

PloS one, 2019-08, Vol.14 (8), p.e0218759-e0218759

2019

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The role of human papillomavirus in head and neck squamous cell carcinoma: A case control study on a southern Chinese population

Journal of medical virology, 2016-05, Vol.88 (5), p.877-887

2016

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High Prevalence and Mechanism Associated With Extended Spectrum Beta-Lactamase-Positive Phenotype in Laribacter hongkongensis

Frontiers in microbiology, 2021-02, Vol.12, p.618894-618894

2021

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MicroRNA-125b Interacts with Foxp3 to Induce Autophagy in Thyroid Cancer

Molecular therapy, 2018-09, Vol.26 (9), p.2295-2303

2018

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Facial emotion perception impairments in schizophrenia patients with comorbid antisocial personality disorder

Psychiatry research, 2016-02, Vol.236, p.22-27

2016

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Functional recovery in a cohort of ECMO and non-ECMO acute respiratory distress syndrome survivors

Critical care (London, England), 2023-11, Vol.27 (1), p.1-440, Article 440

2023

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Dyadic associations between psychological distress and sleep disturbance among Chinese patients with cancer and their spouses

Psycho-oncology (Chichester, England), 2017-06, Vol.26 (6), p.856-861

2017

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The cross‐talk between estrogen receptor and peroxisome proliferator‐activated receptor gamma in thyroid cancer

Cancer, 2014-01, Vol.120 (1), p.142-153

2014

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A risk stratification model for toxicities in phase 1 immunotherapy trials

European journal of cancer (1990), 2022-11, Vol.175, p.11-18

2022

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Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical Relevance

Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control

Celecoxib is a substrate of CYP2D6: Impact on celecoxib metabolism in individuals with CYP2C93 variants

Impact of Probe Substrate Selection on Cytochrome P450 Reaction Phenotyping Using the Relative Activity Factor

Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo

Pharmacokinetic/pharmacodynamic drug–drug interactions of avatrombopag when coadministered with dual or selective CYP2C9 and CYP3A interacting drugs

First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE 2 -receptor E-type 4 (EP4), in patients with advanced cancers

Metabolic disposition of H3B-8800, an orally available small-molecule splicing modulator, in rats, monkeys, and humans

Impact of probe substrates selection on the outcome of CYP reaction phenotyping study

Stereoselective metabolism of pyrido[3,2-D]pyrimidine-containing compounds by aldehyde oxidase

Recommendations for in vitro CYP3A4 mRNA data analysis for drug-drug interaction risk assessment from the IQ Induction working group

Considerations from the IQ induction working group in response to drug–drug interaction guidances from regulatory agencies

First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers

Comprehensive Defensin Assay for Saliva

eFIP: a tool for mining functional impact of phosphorylation from literature

Initial uptake, time to treatment, and real-world effectiveness of all-oral direct-acting antivirals for hepatitis C virus infection in the United States: A retrospective cohort analysis

The role of human papillomavirus in head and neck squamous cell carcinoma: A case control study on a southern Chinese population

High Prevalence and Mechanism Associated With Extended Spectrum Beta-Lactamase-Positive Phenotype in Laribacter hongkongensis

MicroRNA-125b Interacts with Foxp3 to Induce Autophagy in Thyroid Cancer

Facial emotion perception impairments in schizophrenia patients with comorbid antisocial personality disorder

Functional recovery in a cohort of ECMO and non-ECMO acute respiratory distress syndrome survivors

Dyadic associations between psychological distress and sleep disturbance among Chinese patients with cancer and their spouses

The cross‐talk between estrogen receptor and peroxisome proliferator‐activated receptor gamma in thyroid cancer

A risk stratification model for toxicities in phase 1 immunotherapy trials

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