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The Opioid Crisis and the Future of Addiction and Pain Therapeutics

The Journal of pharmacology and experimental therapeutics, 2019-11, Vol.371 (2), p.396-408

2019

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Impact of high-throughput screening in biomedical research

Nature reviews. Drug discovery, 2011-03, Vol.10 (3), p.188-195

2011

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Overcoming Wnt-β-catenin dependent anticancer therapy resistance in leukaemia stem cells

Nature cell biology, 2020-06, Vol.22 (6), p.689-700

2020

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Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response

Cancer research (Chicago, Ill.), 2019-04, Vol.79 (7), p.1681-1695

2019

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The NCATS Assay Guidance Manual programme: advancing the practice and rigour of preclinical translation

Nature reviews. Drug discovery, 2022-12, Vol.21 (12), p.863-864

2022

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Assay Guidance Manual for Drug Discovery: Technologies That Matter

SLAS technology, 2021-12, Vol.26 (6), p.553-554

2021

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A comparison of assay performance measures in screening assays: signal window, Z' factor, and assay variability ratio

Journal of biomolecular screening, 2006-04, Vol.11 (3), p.247-252

2006

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Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays

PloS one, 2015-07, Vol.10 (7), p.e0130796-e0130796

2015

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Fully Three-Dimensional Bioprinted Skin Equivalent Constructs with Validated Morphology and Barrier Function

Tissue engineering. Part C, Methods, 2019-06, Vol.25 (6), p.334-343

2019

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Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs

Pharmacological reviews, 2017-10, Vol.69 (4), p.479-496

2017

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The translational science training program at NIH: Introducing early career researchers to the science and operation of translation of basic research to medical interventions

Biochemistry and molecular biology education, 2017-01, Vol.45 (1), p.13-24

2017

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Effects of respiratory mechanical forces on the pharmacological response of lung cancer cells to chemotherapeutic agents

Fundamental & clinical pharmacology, 2012-10, Vol.26 (5), p.632-643

2012

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Mapping biologically active chemical space to accelerate drug discovery

Nature reviews. Drug discovery, 2019-02, Vol.18 (2), p.83-84

2019

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An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics

New biotechnology, 2023-09, Vol.76, p.13-22

2023

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Assay Guidance Manual for Drug Discovery: Robust or Go Bust

SLAS discovery, 2021-12, Vol.26 (10), p.1241-1242

2021

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Preclinical target validation for non-addictive therapeutics development for pain

Expert opinion on therapeutic targets, 2022-09, Vol.26 (9), p.811-822

2022

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Stem Cells in Drug Discovery, Tissue Engineering, and Regenerative Medicine: Emerging Opportunities and Challenges

Journal of biomolecular screening, 2009-08, Vol.14 (7), p.755-768

2009

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Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery

Clinical and translational science, 2018-09, Vol.11 (5), p.461-470

2018

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Synthesis and Characterization of Insulin−Fluorescein Derivatives for Bioanalytical Applications

Analytical chemistry (Washington), 1997-12, Vol.69 (24), p.4994-5000

1997

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The third international meeting on genetic disorders in the RAS/MAPK pathway: Towards a therapeutic approach

American journal of medical genetics. Part A, 2015-08, Vol.167A (8), p.1741-1746

2015

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Stretching mechanotransduction from the lung to the lab: approaches and physiological relevance in drug discovery

Assay and drug development technologies, 2012-04, Vol.10 (2), p.137-147

2012

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High-throughput screening: advances in assay technologies

Current opinion in chemical biology, 1997-10, Vol.1 (3), p.384-391

1997

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Bioimaging in drug discovery sciences

Analytical and bioanalytical chemistry, 2003-11, Vol.377 (6), p.953-954

2003

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Establishment of a Translational Science and Medicine Training Program in Japan

Translational and regulatory sciences, 2020, Vol.2 (2), p.36-41

2020

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Metastatic Tumor-In-A-Dish, A Novel Multi-Cellular Organoid To Study Lung Colonization and Predict Therapeutic Response

Cancer research (Chicago, Ill.), 2019-01, Vol.79 (7), p.1681-1695

2019

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The Opioid Crisis and the Future of Addiction and Pain Therapeutics

Impact of high-throughput screening in biomedical research

Overcoming Wnt-β-catenin dependent anticancer therapy resistance in leukaemia stem cells

Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response

The NCATS Assay Guidance Manual programme: advancing the practice and rigour of preclinical translation

Assay Guidance Manual for Drug Discovery: Technologies That Matter

A comparison of assay performance measures in screening assays: signal window, Z' factor, and assay variability ratio

Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays

Fully Three-Dimensional Bioprinted Skin Equivalent Constructs with Validated Morphology and Barrier Function

Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs

The translational science training program at NIH: Introducing early career researchers to the science and operation of translation of basic research to medical interventions

Effects of respiratory mechanical forces on the pharmacological response of lung cancer cells to chemotherapeutic agents

Mapping biologically active chemical space to accelerate drug discovery

An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics

Assay Guidance Manual for Drug Discovery: Robust or Go Bust

Preclinical target validation for non-addictive therapeutics development for pain

Stem Cells in Drug Discovery, Tissue Engineering, and Regenerative Medicine: Emerging Opportunities and Challenges

Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery

Synthesis and Characterization of Insulin−Fluorescein Derivatives for Bioanalytical Applications

The third international meeting on genetic disorders in the RAS/MAPK pathway: Towards a therapeutic approach

Stretching mechanotransduction from the lung to the lab: approaches and physiological relevance in drug discovery

High-throughput screening: advances in assay technologies

Bioimaging in drug discovery sciences

Establishment of a Translational Science and Medicine Training Program in Japan

Metastatic Tumor-In-A-Dish, A Novel Multi-Cellular Organoid To Study Lung Colonization and Predict Therapeutic Response

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