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A critical review of the effectiveness of rodent pharmaceutical carcinogenesis testing in predicting for human risk

Veterinary pathology, 2011-05, Vol.48 (3), p.772-784

2011

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Preclinical Predictors of Clinical Safety: Opportunities for Improvement

Clinical pharmacology and therapeutics, 2007-08, Vol.82 (2), p.210-214

2007

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Developmental Neurotoxicity of Ketamine: Morphometric Confirmation, Exposure Parameters, and Multiple Fluorescent Labeling of Apoptotic Neurons

Toxicological sciences, 2004-10, Vol.81 (2), p.364-370

2004

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Novel Biomarkers of Acute Kidney Toxicity

Clinical pharmacology and therapeutics, 2009-11, Vol.86 (5), p.490-496

2009

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An evaluation of chronic 6- and 12-month rat toxicology studies as predictors of 2-year tumor outcome

Veterinary pathology, 2010-07, Vol.47 (4), p.614-629

2010

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Medical applications of microarray technologies: a regulatory science perspective

Nature genetics, 2002-12, Vol.32 Suppl (4s), p.474-479

2002

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A Systematic Approach to Preclinical and Clinical Safety Biomarker Qualification Incorporating Bradford Hill's Principles of Causality Association

Clinical pharmacology and therapeutics, 2010-08, Vol.88 (2), p.260-262

2010

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Effects of Base Stacking on Guanine Electron Transfer: Rate Constants for G and GG Sequences of Oligonucleotides from Catalytic Electrochemistry

Journal of the American Chemical Society, 2000-05, Vol.122 (19), p.4742-4749

2000

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Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells

Mutation research, 2004-05, Vol.549 (1), p.43-64

2004

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Ontogeny of the N-Methyl-D-Aspartate (NMDA) Receptor System and Susceptibility to Neurotoxicity

Toxicological sciences, 2002-07, Vol.68 (1), p.9-17

2002

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Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity

Toxicologic pathology, 2004-01, Vol.32 (1), p.106-121

2004

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Probing Biomolecule Recognition with Electron Transfer: Electrochemical Sensors for DNA Hybridization

Bioconjugate chemistry, 1997-11, Vol.8 (6), p.906-913

1997

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Distribution of P2Y receptor subtypes on haematopoietic cells

British journal of pharmacology, 1998-03, Vol.123 (5), p.789-794

1998

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The Utility of Genetically Modified Mouse Assays for Identifying Human Carcinogens: A Basic Understanding and Path Forward

Toxicological sciences, 2004-02, Vol.77 (2), p.188-194

2004

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THE USE OF IN SITU PERFUSION OF THE RAT MESENTERY AS A MODEL TO INVESTIGATE VASCULAR INJURY DIRECTLY INDUCED BY DRUGS

Methods and Findings in Experimental and Clinical Pharmacology, 2010-09, Vol.32 (7), p.489-497

2010

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Selection of Drugs to Test the Specificity of the Tg.AC Assay by Screening for Induction of the gadd153 Promoter in Vitro

Toxicological sciences, 2003-08, Vol.74 (2), p.260-270

2003

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Electrochemical Studies of Polynucleotide Binding and Oxidation by Metal Complexes: Effects of Scan Rate, Concentration, and Sequence

The journal of physical chemistry. B, 1999-12, Vol.103 (48), p.10718-10728

1999

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The utility of the K6/ODC transgenic mouse as an alternative short term dermal model for carcinogenicity testing of pharmaceuticals

Regulatory toxicology and pharmacology, 2008-02, Vol.50 (1), p.87-97

2008

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Transgenic tumor models for carcinogen identification: the heterozygous Trp53-deficient and RasH2 mouse lines

Mutation research, 2003-10, Vol.540 (2), p.165-176

2003

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Emerging technologies for food and drug safety

Regulatory toxicology and pharmacology, 2018-10, Vol.98, p.115-128

2018

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Alterations in gene expression profiles and the DNA-damage response in ionizing radiation-exposed TK6 cells

Environmental and molecular mutagenesis, 2005, Vol.45 (2-3), p.188-205

2005

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Identification of Putative Gene-Based Markers of Renal Toxicity

Environmental health perspectives, 2004-03, Vol.112 (4), p.465-479

2004

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Evaluation of the Tg.AC Assay: Specificity Testing with Three Noncarcinogenic Pharmaceuticals that Induce Selected Stress Gene Promoters in Vitro and the Inhibitory Effects of Solvent Components

Toxicological sciences, 2003-08, Vol.74 (2), p.271-278

2003

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SK&F 95654-Induced Acute Cardiovascular Toxicity in Sprague-Dawley Rats—Histopathologic, Electron Microscopic, and Immunohistochemical Studies

Toxicologic pathology, 2002-01, Vol.30 (1), p.28-40

2002

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Transgenic animal models that might be useful in identifying unsuspected oncogenic factors in tumour cell substrates

Developments in biologicals, 2001, Vol.106, p.123

Sistare, F D

2001

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A critical review of the effectiveness of rodent pharmaceutical carcinogenesis testing in predicting for human risk

Preclinical Predictors of Clinical Safety: Opportunities for Improvement

Developmental Neurotoxicity of Ketamine: Morphometric Confirmation, Exposure Parameters, and Multiple Fluorescent Labeling of Apoptotic Neurons

Novel Biomarkers of Acute Kidney Toxicity

An evaluation of chronic 6- and 12-month rat toxicology studies as predictors of 2-year tumor outcome

Medical applications of microarray technologies: a regulatory science perspective

A Systematic Approach to Preclinical and Clinical Safety Biomarker Qualification Incorporating Bradford Hill's Principles of Causality Association

Effects of Base Stacking on Guanine Electron Transfer: Rate Constants for G and GG Sequences of Oligonucleotides from Catalytic Electrochemistry

Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells

Ontogeny of the N-Methyl-D-Aspartate (NMDA) Receptor System and Susceptibility to Neurotoxicity

Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity

Probing Biomolecule Recognition with Electron Transfer: Electrochemical Sensors for DNA Hybridization

Distribution of P2Y receptor subtypes on haematopoietic cells

The Utility of Genetically Modified Mouse Assays for Identifying Human Carcinogens: A Basic Understanding and Path Forward

THE USE OF IN SITU PERFUSION OF THE RAT MESENTERY AS A MODEL TO INVESTIGATE VASCULAR INJURY DIRECTLY INDUCED BY DRUGS

Selection of Drugs to Test the Specificity of the Tg.AC Assay by Screening for Induction of the gadd153 Promoter in Vitro

Electrochemical Studies of Polynucleotide Binding and Oxidation by Metal Complexes: Effects of Scan Rate, Concentration, and Sequence

The utility of the K6/ODC transgenic mouse as an alternative short term dermal model for carcinogenicity testing of pharmaceuticals

Transgenic tumor models for carcinogen identification: the heterozygous Trp53-deficient and RasH2 mouse lines

Emerging technologies for food and drug safety

Alterations in gene expression profiles and the DNA-damage response in ionizing radiation-exposed TK6 cells

Identification of Putative Gene-Based Markers of Renal Toxicity

Evaluation of the Tg.AC Assay: Specificity Testing with Three Noncarcinogenic Pharmaceuticals that Induce Selected Stress Gene Promoters in Vitro and the Inhibitory Effects of Solvent Components

SK&F 95654-Induced Acute Cardiovascular Toxicity in Sprague-Dawley Rats—Histopathologic, Electron Microscopic, and Immunohistochemical Studies

Transgenic animal models that might be useful in identifying unsuspected oncogenic factors in tumour cell substrates

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