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Boosting the IL‐22 response using flagellin prevents bacterial infection in cigarette smoke‐exposed mice

Clinical and experimental immunology, 2020-08, Vol.201 (2), p.171-186

2020

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Safety and efficacy of a DKK1 inhibitor (DKN-01) in combination with pembrolizumab (P) in patients (Pts) with advanced gastroesophageal (GE) malignancies

Annals of oncology, 2018-10, Vol.29, p.viii222-viii222

2018

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Response to anti-DKK1 therapy in uterine carcinosarcoma: A case report

Gynecologic oncology reports, 2022-02, Vol.39, p.100904, Article 100904

2022

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Toll-like receptor 2 is critical for induction of Reg3β expression and intestinal clearance of Yersinia pseudotuberculosis

Gut, 2009-06, Vol.58 (6), p.771-776

2009

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PD-016Current results of a phase I study of DKN-01 in combination with paclitaxel (P) in patients (pts) with advanced DKK1+ esophageal cancer (EC) or gastro-esophageal junction tumors (GEJ)

Annals of oncology, 2016-06, Vol.27 (suppl_2), p.ii108-ii108

2016

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Sodium fluoride PET imaging as a quantitative pharmacodynamic biomarker for bone homeostasis during anti-DKK1 therapy for multiple myeloma

Blood cancer journal (New York), 2017-10, Vol.7 (10), p.e615-e615

2017

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Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa

Trends in microbiology (Regular ed.), 2004-11, Vol.12 (11), p.509-517

2004

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Potential biomarkers of response to DKK1 blockade with DKN-01 in combination with paclitaxel in advanced esophagogastric cancer (EGC) patients (pts)

Annals of oncology, 2017-09, Vol.28, p.v24-v24

2017

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Key Role for Respiratory CD103+ Dendritic Cells, IFN- , and IL-17 in Protection Against Streptococcus pneumoniae Infection in Response to -Galactosylceramide

The Journal of infectious diseases, 2012-09, Vol.206 (5), p.723-734

2012

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Role of Toxin Functional Domains in Anthrax Pathogenesis

Infection and Immunity, 2000-04, Vol.68 (4), p.1781-1786

2000

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mTOR-driven glycolysis governs induction of innate immune responses by bronchial epithelial cells exposed to the bacterial component flagellin

Mucosal immunology, 2021-05, Vol.14 (3), p.594-604

2021

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Flagellin Stimulation of Intestinal Epithelial Cells Triggers CCL20-Mediated Migration of Dendritic Cells

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.13722-13727

2001

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Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections

Mucosal immunology, 2017-07, Vol.10 (4), p.1056-1068

2017

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Innate and acquired plasticity of the intestinal immune system

Cellular and molecular life sciences : CMLS, 2005-06, Vol.62 (12), p.1285-1287

2005

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The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature

Journal of Bacteriology, 1994-08, Vol.176 (16), p.5188-5192

1994

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Airway structural cells regulate TLR5-mediated mucosal adjuvant activity

Mucosal immunology, 2014-05, Vol.7 (3), p.489-500

2014

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Characterization of the Bacillus anthracis S-layer: cloning and sequencing of the structural gene

Journal of Bacteriology, 1995-02, Vol.177 (3), p.614-620

1995

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Protective immunity induced by Bacillus anthracis toxin-deficient strains

Infection and Immunity, 1995-04, Vol.63 (4), p.1369-1372

1995

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The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence

Molecular microbiology, 1995-06, Vol.16 (6), p.1171-1181

1995

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Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella

Protein science, 2017-05, Vol.26 (5), p.1049-1059

2017

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Nasal Immunization of Mice with Virus-Like Particles Protects Offspring against Rotavirus Diarrhea

Journal of Virology, 2000-10, Vol.74 (19), p.8966-8971

2000

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1213P DKN-01 and tislelizumab + chemotherapy as first-line (1L) investigational therapy in advanced gastroesophageal adenocarcinoma (GEA): DisTinGuish trial

Annals of oncology, 2022-09, Vol.33, p.S1103-S1104

2022

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Role of Toll‐like receptors in costimulating cytotoxic T cell responses

European journal of immunology, 2003-06, Vol.33 (6), p.1465-1470

2003

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Anti-GITR agonist TRX518 in combination with gemcitabine in advanced solid cancers: Preliminary safety and efficacy from a multi-center phase Ib trial

Annals of oncology, 2018-12, Vol.29, p.x29-x29

2018

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Functional Analysis of the Carboxy-Terminal Domain of Bacillus anthracis Protective Antigen

Infection and Immunity, 1999-02, Vol.67 (2), p.964-967

1999

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Boosting the IL‐22 response using flagellin prevents bacterial infection in cigarette smoke‐exposed mice

Safety and efficacy of a DKK1 inhibitor (DKN-01) in combination with pembrolizumab (P) in patients (Pts) with advanced gastroesophageal (GE) malignancies

Response to anti-DKK1 therapy in uterine carcinosarcoma: A case report

Toll-like receptor 2 is critical for induction of Reg3β expression and intestinal clearance of Yersinia pseudotuberculosis

PD-016Current results of a phase I study of DKN-01 in combination with paclitaxel (P) in patients (pts) with advanced DKK1+ esophageal cancer (EC) or gastro-esophageal junction tumors (GEJ)

Sodium fluoride PET imaging as a quantitative pharmacodynamic biomarker for bone homeostasis during anti-DKK1 therapy for multiple myeloma

Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa

Potential biomarkers of response to DKK1 blockade with DKN-01 in combination with paclitaxel in advanced esophagogastric cancer (EGC) patients (pts)

Key Role for Respiratory CD103+ Dendritic Cells, IFN- , and IL-17 in Protection Against Streptococcus pneumoniae Infection in Response to -Galactosylceramide

Role of Toxin Functional Domains in Anthrax Pathogenesis

mTOR-driven glycolysis governs induction of innate immune responses by bronchial epithelial cells exposed to the bacterial component flagellin

Flagellin Stimulation of Intestinal Epithelial Cells Triggers CCL20-Mediated Migration of Dendritic Cells

Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections

Innate and acquired plasticity of the intestinal immune system

The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature

Airway structural cells regulate TLR5-mediated mucosal adjuvant activity

Characterization of the Bacillus anthracis S-layer: cloning and sequencing of the structural gene

Protective immunity induced by Bacillus anthracis toxin-deficient strains

The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence

Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella

Nasal Immunization of Mice with Virus-Like Particles Protects Offspring against Rotavirus Diarrhea

1213P DKN-01 and tislelizumab + chemotherapy as first-line (1L) investigational therapy in advanced gastroesophageal adenocarcinoma (GEA): DisTinGuish trial

Role of Toll‐like receptors in costimulating cytotoxic T cell responses

Anti-GITR agonist TRX518 in combination with gemcitabine in advanced solid cancers: Preliminary safety and efficacy from a multi-center phase Ib trial

Functional Analysis of the Carboxy-Terminal Domain of Bacillus anthracis Protective Antigen

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