UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Evaluation of Various Static and Dynamic Modeling Methods to Predict Clinical CYP3A Induction Using In Vitro CYP3A4 mRNA Induction Data

Clinical pharmacology and therapeutics, 2014-02, Vol.95 (2), p.179-188

2014

Volltextzugriff (PDF)

Evaluation of CYP2B6 Induction and Prediction of Clinical Drug-Drug Interactions: Considerations from the IQ Consortium Induction Working Group-An Industry Perspective

Drug metabolism and disposition, 2016-10, Vol.44 (10), p.1720-1730

2016

Volltextzugriff (PDF)

Evaluation of pregnane X receptor (PXR)-mediated CYP3A4 drug-drug interactions in drug development

Drug metabolism reviews, 2013-02, Vol.45 (1), p.3-14

Sinz, Michael W.

2013

Volltextzugriff (PDF)

Cytochrome P450 reaction-phenotyping: an industrial perspective

Expert opinion on drug metabolism & toxicology, 2007-10, Vol.3 (5), p.667-687

2007

Volltextzugriff (PDF)

Machine Learning Methods and Docking for Predicting Human Pregnane X Receptor Activation

Chemical research in toxicology, 2008-07, Vol.21 (7), p.1457-1467

2008

Volltextzugriff (PDF)

Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice

Chemical research in toxicology, 1998-04, Vol.11 (4), p.252-259

1998

Volltextzugriff (PDF)

The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Journal of medicinal chemistry, 2014-03, Vol.57 (5), p.1730-1752

2014

Volltextzugriff (PDF)

Development and full validation of six inhibition assays for five major cytochrome P450 enzymes in human liver microsomes using an automated 96-well microplate incubation format and LC–MS/MS analysis

Journal of pharmaceutical and biomedical analysis, 2007-05, Vol.44 (1), p.211-223

2007

Volltextzugriff (PDF)

Expression and characterization of cynomolgus monkey cytochrome CYP3A4 in a novel human embryonic kidney cell-based mammalian system

Drug metabolism and disposition, 2014-03, Vol.42 (3), p.369-376

2014

Volltextzugriff (PDF)

Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition

Drug metabolism and disposition, 2003-04, Vol.31 (4), p.439-446

2003

Volltextzugriff (PDF)

Phenacetin pharmacokinetics in CYP1A2-deficient beagle dogs

Drug metabolism and disposition, 2012-02, Vol.40 (2), p.228-231

2012

Volltextzugriff (PDF)

Meet Our Editor

Current drug metabolism, 2017-01, Vol.18 (1), p.2-2

Sinz, Michael

2017

Volltextzugriff (PDF)

Development and evaluation of potential accident scenarios involving pedestrians and AEB-equipped vehicles to demonstrate the efficiency of an enhanced open-source simulation framework

Accident analysis and prevention, 2020-12, Vol.148, p.105831-105831, Article 105831

2020

Volltextzugriff (PDF)

Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1

Bioorganic & medicinal chemistry letters, 2023-05, Vol.88, p.129280-129280, Article 129280

2023

Volltextzugriff (PDF)

Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Journal of medicinal chemistry, 2014-03, Vol.57 (5), p.1708-1729

2014

Volltextzugriff (PDF)

Fluorine Substitution Can Block CYP3A4 Metabolism-Dependent Inhibition: Identification of (S)-N-[1-(4-Fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an Orally Bioavailable KCNQ2 Opener Devoid of CYP3A4 Metabolism-Dependent Inhibition

Journal of medicinal chemistry, 2003-08, Vol.46 (18), p.3778-3781

2003

Volltextzugriff (PDF)

Required length of guardrails before hazards

Accident analysis and prevention, 2011-11, Vol.43 (6), p.2112-2120

2011

Volltextzugriff (PDF)

Meet Our Editor

Current drug metabolism, 2015-10, Vol.16 (6), p.411-411

Sinz, Michael

2015

Volltextzugriff (PDF)

An insulin-like growth factor 1 receptor inhibitor induces CYP3A4 expression through a pregnane X receptor-independent, noncanonical constitutive androstane receptor-related mechanism

The Journal of pharmacology and experimental therapeutics, 2012-03, Vol.340 (3), p.688-697

2012

Volltextzugriff (PDF)

The effect of troglitazone biliary excretion on metabolite distribution and cholestasis in transporter-deficient rats

Drug metabolism and disposition, 2001-12, Vol.29 (12), p.1561

2001

Volltextzugriff (PDF)

Identification of novel glutathione conjugates of terbinafine in liver microsomes and hepatocytes across species

Xenobiotica, 2019-12, Vol.49 (12), p.1403-1413

2019

Volltextzugriff (PDF)

Metabolism and transporter-mediated drug–drug interactions of the endothelin-A receptor antagonist CI-1034

Chemico-biological interactions, 2006-02, Vol.159 (2), p.156-168

2006

Volltextzugriff (PDF)

integrated physical and genetic map of the nematode Pristionchus pacificus

Molecular genetics and genomics : MGG, 2003-08, Vol.269 (5), p.715-722

2003

Volltextzugriff (PDF)

Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.8042-8060

2016

Volltextzugriff (PDF)

Influences of pre-crash braking induced dummy – Forward displacements on dummy behaviour during EuroNCAP frontal crashtest

Accident analysis and prevention, 2014-01, Vol.62, p.268-275

2014

Volltextzugriff (PDF)

1 – 25 von 149

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(122)
Mit Volltextzugriff
(99)

Publikationsform

Sprache

Englisch
(143)
Deutsch
(6)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Evaluation of Various Static and Dynamic Modeling Methods to Predict Clinical CYP3A Induction Using In Vitro CYP3A4 mRNA Induction Data

Evaluation of CYP2B6 Induction and Prediction of Clinical Drug-Drug Interactions: Considerations from the IQ Consortium Induction Working Group-An Industry Perspective

Evaluation of pregnane X receptor (PXR)-mediated CYP3A4 drug-drug interactions in drug development

Cytochrome P450 reaction-phenotyping: an industrial perspective

Machine Learning Methods and Docking for Predicting Human Pregnane X Receptor Activation

Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice

The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Development and full validation of six inhibition assays for five major cytochrome P450 enzymes in human liver microsomes using an automated 96-well microplate incubation format and LC–MS/MS analysis

Expression and characterization of cynomolgus monkey cytochrome CYP3A4 in a novel human embryonic kidney cell-based mammalian system

Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition

Phenacetin pharmacokinetics in CYP1A2-deficient beagle dogs

Meet Our Editor

Development and evaluation of potential accident scenarios involving pedestrians and AEB-equipped vehicles to demonstrate the efficiency of an enhanced open-source simulation framework

Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1

Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Fluorine Substitution Can Block CYP3A4 Metabolism-Dependent Inhibition: Identification of (S)-N-[1-(4-Fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an Orally Bioavailable KCNQ2 Opener Devoid of CYP3A4 Metabolism-Dependent Inhibition

Required length of guardrails before hazards

Meet Our Editor

An insulin-like growth factor 1 receptor inhibitor induces CYP3A4 expression through a pregnane X receptor-independent, noncanonical constitutive androstane receptor-related mechanism

The effect of troglitazone biliary excretion on metabolite distribution and cholestasis in transporter-deficient rats

Identification of novel glutathione conjugates of terbinafine in liver microsomes and hepatocytes across species

Metabolism and transporter-mediated drug–drug interactions of the endothelin-A receptor antagonist CI-1034

integrated physical and genetic map of the nematode Pristionchus pacificus

Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing

Influences of pre-crash braking induced dummy – Forward displacements on dummy behaviour during EuroNCAP frontal crashtest

Suchergebnisse filtern