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Integration of multiomics data shows down regulation of mismatch repair and tubulin pathways in triple-negative chemotherapy-resistant breast tumors

Breast cancer research : BCR, 2023-05, Vol.25 (1), p.57-18, Article 57

2023

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Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies

PloS one, 2021-04, Vol.16 (4), p.e0249305-e0249305

2021

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Identification of missing variants by combining multiple analytic pipelines

BMC bioinformatics, 2018-04, Vol.19 (1), p.139-139, Article 139

2018

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Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

Pharmacogenetics and genomics, 2019-10, Vol.29 (8), p.183-191

2019

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Polygenic risk for prostate cancer: Decreasing relative risk with age but little impact on absolute risk

American journal of human genetics, 2022-05, Vol.109 (5), p.900-908

2022

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Automated mitotic spindle hotspot counts are highly associated with clinical outcomes in systemically untreated early-stage triple-negative breast cancer

NPJ breast cancer, 2024-03, Vol.10 (1), p.25-25, Article 25

2024

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Determining the frequency of pathogenic germline variants from exome sequencing in patients with castrate-resistant prostate cancer

BMJ open, 2016-04, Vol.6 (4), p.e010332-e010332

2016

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The kinship2 R Package for Pedigree Data

Human heredity, 2014-01, Vol.78 (2), p.91-93

2014

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Penalized models for analysis of multiple mediators

Genetic epidemiology, 2020-07, Vol.44 (5), p.408-424

2020

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Utility of ALK-1 protein expression and ALK rearrangements in distinguishing inflammatory myofibroblastic tumor from malignant spindle cell lesions of the urinary bladder

Modern pathology, 2007-05, Vol.20 (5), p.592-603

2007

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Statistical Methods for Testing Genetic Pleiotropy

Genetics (Austin), 2016-10, Vol.204 (2), p.483-497

2016

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Penalized mediation models for multivariate data

Genetic epidemiology, 2022-02, Vol.46 (1), p.32-50

2022

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CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma

Human pathology, 2009-09, Vol.40 (9), p.1296-1303

2009

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Penalized variance components for association of multiple genes with traits

Genetic epidemiology, 2020-10, Vol.44 (7), p.665-675

2020

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Biomarkers for Predicting Abiraterone Treatment Outcome and Selecting Alternative Therapies in Castration‐Resistant Prostate Cancer

Clinical pharmacology and therapeutics, 2022-06, Vol.111 (6), p.1296-1306

2022

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Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data

Genetic epidemiology, 2013-07, Vol.37 (5), p.409-418

2013

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Molecular Profile Changes in Patients with Castrate-Resistant Prostate Cancer Pre- and Post-Abiraterone/Prednisone Treatment

Molecular cancer research, 2022-12, Vol.20 (12), p.1739-1750

2022

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Multivariate generalized linear model for genetic pleiotropy

Biostatistics (Oxford, England), 2019-01, Vol.20 (1), p.111-128

2019

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Breast Cancer Polygenic-Risk Score Influence on Risk-Reducing Endocrine Therapy Use: Genetic Risk Estimate (GENRE) Trial 1-Year and 2-Year Follow-Up

Cancer prevention research (Philadelphia, Pa.), 2024-02, Vol.17 (2), p.77-84

2024

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Discovery of a Glucocorticoid Receptor (GR) Activity Signature Using Selective GR Antagonism in ER-Negative Breast Cancer

Clinical cancer research, 2018-07, Vol.24 (14), p.3433-3446

2018

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Patient-Derived Xenograft Engraftment and Breast Cancer Outcomes in a Prospective Neoadjuvant Study (BEAUTY)

Clinical cancer research, 2021-09, Vol.27 (17), p.4696-4699

2021

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A Prospective Correlation of Tissue Histopathology With Nucleic Acid Yield in Metastatic Castration-Resistant Prostate Cancer Biopsy Specimens

Mayo Clinic proceedings. Innovations, quality & outcomes, 2019-03, Vol.3 (1), p.14-22

2019

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Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

JNCI : Journal of the National Cancer Institute, 2017-07, Vol.109 (7)

2017

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Nine-gene pharmacogenomics profile service: The Mayo Clinic experience

The pharmacogenomics journal, 2022-02, Vol.22 (1), p.69-74

2022

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Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

Breast cancer research : BCR, 2017-12, Vol.19 (1), p.130-130, Article 130

2017

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Integration of multiomics data shows down regulation of mismatch repair and tubulin pathways in triple-negative chemotherapy-resistant breast tumors

Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies

Identification of missing variants by combining multiple analytic pipelines

Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

Polygenic risk for prostate cancer: Decreasing relative risk with age but little impact on absolute risk

Automated mitotic spindle hotspot counts are highly associated with clinical outcomes in systemically untreated early-stage triple-negative breast cancer

Determining the frequency of pathogenic germline variants from exome sequencing in patients with castrate-resistant prostate cancer

The kinship2 R Package for Pedigree Data

Penalized models for analysis of multiple mediators

Utility of ALK-1 protein expression and ALK rearrangements in distinguishing inflammatory myofibroblastic tumor from malignant spindle cell lesions of the urinary bladder

Statistical Methods for Testing Genetic Pleiotropy

Penalized mediation models for multivariate data

CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma

Penalized variance components for association of multiple genes with traits

Biomarkers for Predicting Abiraterone Treatment Outcome and Selecting Alternative Therapies in Castration‐Resistant Prostate Cancer

Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data

Molecular Profile Changes in Patients with Castrate-Resistant Prostate Cancer Pre- and Post-Abiraterone/Prednisone Treatment

Multivariate generalized linear model for genetic pleiotropy

Breast Cancer Polygenic-Risk Score Influence on Risk-Reducing Endocrine Therapy Use: Genetic Risk Estimate (GENRE) Trial 1-Year and 2-Year Follow-Up

Discovery of a Glucocorticoid Receptor (GR) Activity Signature Using Selective GR Antagonism in ER-Negative Breast Cancer

Patient-Derived Xenograft Engraftment and Breast Cancer Outcomes in a Prospective Neoadjuvant Study (BEAUTY)

A Prospective Correlation of Tissue Histopathology With Nucleic Acid Yield in Metastatic Castration-Resistant Prostate Cancer Biopsy Specimens

Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

Nine-gene pharmacogenomics profile service: The Mayo Clinic experience

Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

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