UB Paderborn / Katalog / Suche / in CDI

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (44), p.18825-18830

2009

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Therapeutic approaches to CFTR dysfunction: From discovery to drug development

Journal of cystic fibrosis, 2018-03, Vol.17 (2), p.S14-S21

2018

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Novel Correctors and Potentiators Enhance Translational Readthrough in CFTR Nonsense Mutations

American journal of respiratory cell and molecular biology, 2021-05, Vol.64 (5), p.604-616

2021

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Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222

The Journal of pharmacology and experimental therapeutics, 2020-01, Vol.372 (1), p.107

2020

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Identification of GLPG/ABBV-2737, a Novel Class of Corrector, Which Exerts Functional Synergy With Other CFTR Modulators

Frontiers in pharmacology, 2019-05, Vol.10, p.514-514

2019

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Novel Pseudomonas aeruginosa Quorum-Sensing Inhibitors Identified in an Ultra-High-Throughput Screen

Antimicrobial Agents and Chemotherapy, 2006-11, Vol.50 (11), p.3674-3679

2006

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Diversity of CFTR variants across ancestries characterized using 454,727 UK biobank whole exome sequences

Genome medicine, 2024-03, Vol.16 (1), p.43-14, Article 43

2024

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Bicarbonate and chloride secretion in Calu-3 human airway epithelial cells

The Journal of general physiology, 1999-05, Vol.113 (5), p.743-760

1999

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Discovery of 4‑[(2R,4R)‑4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro‑2H‑chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis

Journal of medicinal chemistry, 2018-02, Vol.61 (4), p.1436-1449

2018

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Pharmacological activation of cloned intermediate- and small-conductance Ca2+-activated K+ channels

American Journal of Physiology: Cell Physiology, 2000-03, Vol.278 (3), p.C570

2000

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Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules

American journal of physiology. Lung cellular and molecular physiology, 2006-06, Vol.290 (6), p.L1117-L1130

2006

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Discovery and SAR of 4-aminopyrrolidine-2-carboxylic acid correctors of CFTR for the treatment of cystic fibrosis

Bioorganic & medicinal chemistry letters, 2022-09, Vol.72, p.128843-128843, Article 128843

2022

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Facial Recognition System with Attendance Tracking Using Python and Open CV

International Journal of Innovative Research in Advanced Engineering, 2024-02, Vol.11 (2), p.110-119

2024

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Discovery of 4-[(2 R ,4 R )-4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2 H -chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis

Journal of medicinal chemistry, 2018-02, Vol.61 (4), p.1436-1449

2018

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Neurotransmitter-stimulated ion transport by cultured porcine vas deferens epithelium

American journal of physiology. Renal physiology, 2001-09, Vol.281 (3), p.F557-F570

2001

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Transepithelial fluctuation analysis of chloride secretion

Journal of cystic fibrosis, 2004-08, Vol.3, p.127-132

2004

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Estrogen inhibition of cystic fibrosis transmembrane conductance regulator-mediated chloride secretion

The Journal of pharmacology and experimental therapeutics, 2000-10, Vol.295 (1), p.195

2000

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Transepithelial impedance analysis of chloride secretion

Methods in molecular medicine, 2002, Vol.70, p.129

2002

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Inhibition of enterotoxin-induced porcine colonic secretion by diarylsulfonylureas in vitro

American journal of physiology: Gastrointestinal and liver physiology, 2000-11, Vol.279 (5), p.G1104-G1112

2000

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Pharmacological activation of cloned intermediate- and small-conductance Ca(2+)-activated K(+) channels

American Journal of Physiology: Cell Physiology, 2000-03, Vol.278 (3), p.C570-C581

2000

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Mycoplasma pulmonis Inhibits Electrogenic Ion Transport across Murine Tracheal Epithelial Cell Monolayers

Infection and Immunity, 1998-01, Vol.66 (1), p.272-279

1998

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Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca(2+)-dependent K+ channel

American journal of physiology. Lung cellular and molecular physiology, 1996-11, Vol.271 (5), p.775-L784

1996

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Effect of Salmonella enterica subspecies enterica serovar Typhimurium and Serratia fonticola on germination of seeds of common crops

Journal of infection in developing countries, 2007-08, Vol.1 (1), p.67-71

Bhoj Raj Singh, Ashvani Kumar, Sugandh Agrawal and Anita Verma

2007

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Inhibitory effect of silibinin on ligand binding to erbB1 and associated mitogenic signaling, growth, and DNA synthesis in advanced human prostate carcinoma cells

Molecular carcinogenesis, 2001, Vol.30 (4), p.224-236

2001

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Glibenclamide blockade of CFTR chloride channels

American journal of physiology. Lung cellular and molecular physiology, 1996-08, Vol.271 (2), p.192-L200

1996

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Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Therapeutic approaches to CFTR dysfunction: From discovery to drug development

Novel Correctors and Potentiators Enhance Translational Readthrough in CFTR Nonsense Mutations

Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222

Identification of GLPG/ABBV-2737, a Novel Class of Corrector, Which Exerts Functional Synergy With Other CFTR Modulators

Novel Pseudomonas aeruginosa Quorum-Sensing Inhibitors Identified in an Ultra-High-Throughput Screen

Diversity of CFTR variants across ancestries characterized using 454,727 UK biobank whole exome sequences

Bicarbonate and chloride secretion in Calu-3 human airway epithelial cells

Discovery of 4‑[(2R,4R)‑4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro‑2H‑chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis

Pharmacological activation of cloned intermediate- and small-conductance Ca2+-activated K+ channels

Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules

Discovery and SAR of 4-aminopyrrolidine-2-carboxylic acid correctors of CFTR for the treatment of cystic fibrosis

Facial Recognition System with Attendance Tracking Using Python and Open CV

Discovery of 4-[(2 R ,4 R )-4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2 H -chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis

Neurotransmitter-stimulated ion transport by cultured porcine vas deferens epithelium

Transepithelial fluctuation analysis of chloride secretion

Estrogen inhibition of cystic fibrosis transmembrane conductance regulator-mediated chloride secretion

Transepithelial impedance analysis of chloride secretion

Inhibition of enterotoxin-induced porcine colonic secretion by diarylsulfonylureas in vitro

Pharmacological activation of cloned intermediate- and small-conductance Ca(2+)-activated K(+) channels

Mycoplasma pulmonis Inhibits Electrogenic Ion Transport across Murine Tracheal Epithelial Cell Monolayers

Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca(2+)-dependent K+ channel

Effect of Salmonella enterica subspecies enterica serovar Typhimurium and Serratia fonticola on germination of seeds of common crops

Inhibitory effect of silibinin on ligand binding to erbB1 and associated mitogenic signaling, growth, and DNA synthesis in advanced human prostate carcinoma cells

Glibenclamide blockade of CFTR chloride channels

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