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Effects of heterozygous deletion of autism-related gene Cullin-3 in mice

PloS one, 2023-07, Vol.18 (7), p.e0283299-e0283299

2023

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Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation

The Journal of experimental medicine, 2017-04, Vol.214 (4), p.1093-1109

2017

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Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells

Science (American Association for the Advancement of Science), 2018-09, Vol.361 (6407)

2018

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Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis

Nature medicine, 2019-11, Vol.25 (11), p.1772-1782

2019

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Cul3 is required for normal development of the mammary gland

Cell and tissue research, 2021-07, Vol.385 (1), p.49-63

2021

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Autism risk gene Cul3 alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons

Frontiers in cellular neuroscience, 2024-05, Vol.18, p.1320784-1320784

2024

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Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3

The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4723-4736

2014

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BTB―ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs

Nature (London), 2012-11, Vol.491 (7425), p.618-621

2012

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Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

American journal of physiology. Renal physiology, 2018-10, Vol.315 (4), p.F1006-F1018

2018

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Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy

Human molecular genetics, 2016-06, Vol.25 (11), p.2143-2157

2016

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Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E

Journal of cell science, 2019-11, Vol.132 (21)

2019

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A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts

Immunity (Cambridge, Mass.), 2022-03, Vol.55 (3), p.494-511.e11

2022

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The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer

Molecular biology of the cell, 2007-03, Vol.18 (3), p.899-909

2007

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Toward medical dystopia

The journal of trauma and acute care surgery, 2013-09, Vol.75 (3), p.517-519

Singer, Jeffrey A

2013

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Daughter’s Tolerance of Mom Matters in Mate Choice

Cell, 2015-07, Vol.162 (3), p.467-469

2015

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Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis

Scientific reports, 2019-03, Vol.9 (1), p.4596, Article 4596

2019

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Subcellular localization and cytoplasmic complex status of endogenous Keap1

Genes to cells : devoted to molecular & cellular mechanisms, 2007-10, Vol.12 (10), p.1163-1178

2007

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Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension

Biochemical and biophysical research communications, 2016-01, Vol.469 (1), p.44-48

2016

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Cullin 3-Mediated Regulation of Intracellular Iron Homeostasis Promotes Thymic Invariant NKT Cell Maturation

ImmunoHorizons, 2023-03, Vol.7 (3), p.235-242

2023

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Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice

The Journal of clinical investigation, 2010-10, Vol.120 (10), p.3713-3721

2010

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The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells

The Journal of clinical investigation, 2010-11, Vol.120 (11), p.3820-3833

2010

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Multisite Phosphorylation by Cdk2 and GSK3 Controls Cyclin E Degradation

Molecular cell, 2003-08, Vol.12 (2), p.381-392

2003

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Constitutive Turnover of Cyclin E by Cul3 Maintains Quiescence

Molecular and Cellular Biology, 2007-05, Vol.27 (10), p.3651-3666

2007

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Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects

JCI insight, 2017-12, Vol.2 (24)

2017

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Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension

JCI insight, 2019-07, Vol.5 (14)

2019

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Effects of heterozygous deletion of autism-related gene Cullin-3 in mice

Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells

Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis

Cul3 is required for normal development of the mammary gland

Autism risk gene Cul3 alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons

Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3

BTB―ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy

Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E

A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts

The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer

Toward medical dystopia

Daughter’s Tolerance of Mom Matters in Mate Choice

Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis

Subcellular localization and cytoplasmic complex status of endogenous Keap1

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension

Cullin 3-Mediated Regulation of Intracellular Iron Homeostasis Promotes Thymic Invariant NKT Cell Maturation

Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice

The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells

Multisite Phosphorylation by Cdk2 and GSK3 Controls Cyclin E Degradation

Constitutive Turnover of Cyclin E by Cul3 Maintains Quiescence

Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects

Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension

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