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In vitro to in vivo extrapolation for high throughput prioritization and decision making

Toxicology in vitro, 2018-03, Vol.47, p.213-227

2018

Volltextzugriff (PDF)

Environmental Risk Assessment: A Toxicological Approach

Simon, Ted W.

Second edition., 2020

Volltextzugriff (PDF)

Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes

Regulatory toxicology and pharmacology, 2015-04, Vol.71 (3), p.463-477

2015

Volltextzugriff (PDF)

Providing context for phosphatidylethanol as a biomarker of alcohol consumption with a pharmacokinetic model

Regulatory toxicology and pharmacology, 2018-04, Vol.94, p.163-171

Simon, Ted W.

2018

Volltextzugriff (PDF)

A model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activators

PloS one, 2015-06, Vol.10 (6), p.e0127952

2015

Volltextzugriff (PDF)

The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events

Critical reviews in toxicology, 2014-08, Vol.44 (S3), p.17-43

2014

Volltextzugriff (PDF)

An exposure:activity profiling method for interpreting high-throughput screening data for estrogenic activity—Proof of concept

Regulatory toxicology and pharmacology, 2015-04, Vol.71 (3), p.398-408

2015

Volltextzugriff (PDF)

Letter to the Editor: Modeling the changing face of Phosphatidylethanol's window of detection

Regulatory toxicology and pharmacology, 2024-01, Vol.146, p.105537-105537, Article 105537

2024

Volltextzugriff (PDF)

Commentary: Value of information case study strongly supports use of the Threshold of Toxicological Concern (TTC)

Regulatory toxicology and pharmacology, 2024-05, Vol.149, p.105594-105594, Article 105594

2024

Volltextzugriff (PDF)

Species differences in specific ligand-binding affinity and activation of AHR: The biological basis for calculation of relative effective potencies and toxic equivalence factors

Regulatory toxicology and pharmacology, 2024-05, Vol.149, p.105598-105598, Article 105598

2024

Volltextzugriff (PDF)

The 2022 revised WHO TEFs for dioxins and dioxin-like chemicals: The importance of considering the use of species-specific information to determine relative effective potency for human-based risk assessment

Regulatory toxicology and pharmacology, 2024-05, Vol.149, p.105599-105599, Article 105599

2024

Volltextzugriff (PDF)

Bayesian methods for uncertainty factor application for derivation of reference values

Regulatory toxicology and pharmacology, 2016-10, Vol.80, p.9-24

2016

Volltextzugriff (PDF)

How well can carcinogenicity be predicted by high throughput “characteristics of carcinogens” mechanistic data?

Regulatory toxicology and pharmacology, 2017-11, Vol.90, p.185-196

2017

Volltextzugriff (PDF)

The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor

Regulatory toxicology and pharmacology, 2015-10, Vol.73 (1), p.172-190

2015

Volltextzugriff (PDF)

Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals

Computational toxicology, 2018-08, Vol.7, p.58-67

2018

Volltextzugriff (PDF)

Can the Predictive Analytics Toolkit (PAT) handle a genomic data set?

Computational toxicology, 2022-11, Vol.24, p.100241, Article 100241

2022

Volltextzugriff (PDF)

Two-Dimensional Monte Carlo Simulation and Beyond: A Comparison of Several Probabilistic Risk Assessment Methods Applied to a Superfund Site

Human and ecological risk assessment, 1999-08, Vol.5 (4), p.823-843

Simon, Ted W.

1999

Volltextzugriff (PDF)

Exposure Assessment

Environmental Risk Assessment, 2020, p.129-190

Simon, Ted W.

2nd Edition, 2020

Volltextzugriff (PDF)

Perception, Planning, and Scoping, Problem Formulation, and Hazard Identification: All Parts of Risk Assessment

Environmental Risk Assessment, 2020, p.63-112

Simon, Ted W.

2nd Edition, 2020

Volltextzugriff (PDF)

Ecological Risk Assessment

Environmental Risk Assessment, 2020, p.365-430

Simon, Ted W.

2nd Edition, 2020

Volltextzugriff (PDF)

Emerging Risks and Final Thoughts

Environmental Risk Assessment, 2020, p.475-484

Simon, Ted W.

2nd Edition, 2020

Volltextzugriff (PDF)

Hazard Characterization and Dose–Response Assessment

Environmental Risk Assessment, 2020, p.191-274

Simon, Ted W.

2nd Edition, 2020

Volltextzugriff (PDF)

An Introduction to Risk Assessment with a Nod to History

Environmental Risk Assessment, 2020, p.1-62

Simon, Ted W.

2nd Edition, 2020

Volltextzugriff (PDF)

Risk Characterization

Environmental Risk Assessment, 2020, p.275-364

Simon, Ted W.

2nd Edition, 2020

Volltextzugriff (PDF)

A Risk Analyst’s Toolbox

Environmental Risk Assessment, 2020, p.113-128

Simon, Ted W.

2nd Edition, 2020

Volltextzugriff (PDF)

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In vitro to in vivo extrapolation for high throughput prioritization and decision making

Environmental Risk Assessment: A Toxicological Approach

Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes

Providing context for phosphatidylethanol as a biomarker of alcohol consumption with a pharmacokinetic model

A model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activators

The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events

An exposure:activity profiling method for interpreting high-throughput screening data for estrogenic activity—Proof of concept

Letter to the Editor: Modeling the changing face of Phosphatidylethanol's window of detection

Commentary: Value of information case study strongly supports use of the Threshold of Toxicological Concern (TTC)

Species differences in specific ligand-binding affinity and activation of AHR: The biological basis for calculation of relative effective potencies and toxic equivalence factors

The 2022 revised WHO TEFs for dioxins and dioxin-like chemicals: The importance of considering the use of species-specific information to determine relative effective potency for human-based risk assessment

Bayesian methods for uncertainty factor application for derivation of reference values

How well can carcinogenicity be predicted by high throughput “characteristics of carcinogens” mechanistic data?

The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor

Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals

Can the Predictive Analytics Toolkit (PAT) handle a genomic data set?

Two-Dimensional Monte Carlo Simulation and Beyond: A Comparison of Several Probabilistic Risk Assessment Methods Applied to a Superfund Site

Exposure Assessment

Perception, Planning, and Scoping, Problem Formulation, and Hazard Identification: All Parts of Risk Assessment

Ecological Risk Assessment

Emerging Risks and Final Thoughts

Hazard Characterization and Dose–Response Assessment

An Introduction to Risk Assessment with a Nod to History

Risk Characterization

A Risk Analyst’s Toolbox

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