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Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?

Neuropharmacology, 2018-05, Vol.133, p.233-241

2018

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Ketone bodies mediate antiseizure effects through mitochondrial permeability transition

Annals of neurology, 2015-07, Vol.78 (1), p.77-87

2015

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Ketogenic diet treatment increases longevity in Kcna1‐null mice, a model of sudden unexpected death in epilepsy

Epilepsia (Copenhagen), 2016-08, Vol.57 (8), p.e178-e182

2016

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Ketone Bodies as Anti-Seizure Agents

Neurochemical research, 2017-07, Vol.42 (7), p.2011-2018

2017

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Altered ventilatory responses to hypercapnia-hypoxia challenges in a preclinical SUDEP model involve orexin neurons

Neurobiology of disease, 2024-09, Vol.199, p.106592, Article 106592

2024

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Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy

Experimental neurology, 2017-01, Vol.287 (Pt 1), p.54-64

2017

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Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin

Epilepsia (Copenhagen), 2020-03, Vol.61 (3), p.572-588

2020

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Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures

Experimental neurology, 2014-01, Vol.251, p.84-90

2014

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Dietary and Metabolic Approaches for Treating Autism Spectrum Disorders, Affective Disorders and Cognitive Impairment Comorbid with Epilepsy: A Review of Clinical and Preclinical Evidence

Nutrients, 2024-02, Vol.16 (4), p.553

2024

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Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice

Sleep (New York, N.Y.), 2016-02, Vol.39 (2), p.357-368

2016

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Accumulation of rest deficiency precedes sudden death of epileptic Kv1.1 knockout mice, a model of sudden unexpected death in epilepsy

Epilepsia (Copenhagen), 2018-01, Vol.59 (1), p.92-105

2018

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Pharmacoresponsiveness of spontaneous recurrent seizures and the comorbid sleep disorder of epileptic Kcna1-null mice

European journal of pharmacology, 2021-12, Vol.913, p.174656-174656, Article 174656

2021

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Synergistic protection against acute flurothyl‐induced seizures by adjuvant treatment of the ketogenic diet with the type 2 diabetes drug pioglitazone

Epilepsia (Copenhagen), 2017-08, Vol.58 (8), p.1440-1450

2017

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Ketogenic diet–mediated seizure reduction preserves CA1 cell numbers in epileptic Kcna1‐null mice: An unbiased stereological assessment

Epilepsia (Copenhagen), 2021-08, Vol.62 (8), p.e123-e128

2021

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Ketogenic diet regulates the antioxidant catalase via the transcription factor PPARγ2

Epilepsy research, 2018-11, Vol.147, p.71-74

2018

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Respiratory dysfunction progresses with age in Kcna1‐null mice, a model of sudden unexpected death in epilepsy

Epilepsia (Copenhagen), 2018-02, Vol.59 (2), p.345-357

2018

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Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices

Neurobiology of disease, 2013-06, Vol.54, p.68-81

2013

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Adenosine has two faces: Regionally dichotomous adenosine tone in a model of epilepsy with comorbid sleep disorders

Neurobiology of disease, 2018-06, Vol.114, p.45-52

2018

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Orexin receptors regulate hippocampal sharp wave-ripple complexes in ex vivo slices

European journal of pharmacology, 2023-07, Vol.950, p.175763-175763, Article 175763

2023

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Ascorbic Acid Reduces Neurotransmission, Synaptic Plasticity, and Spontaneous Hippocampal Rhythms in In Vitro Slices

Nutrients, 2022-01, Vol.14 (3), p.613

2022

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Personalization of SUDEP risk: A survey of transient subclinical comorbid changes

Epilepsy research, 2024-01, Vol.199, p.107259-107259, Article 107259

2024

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Functional MRI Correlates of Carbon Dioxide Chemosensing in Persons With Epilepsy

Frontiers in neurology, 2022-07, Vol.13, p.896204

2022

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Ketone bodies are protective against oxidative stress in neocortical neurons

Journal of neurochemistry, 2007-06, Vol.101 (5), p.1316-1326

2007

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Carbamazepine Reduces Sharp Wave-Ripple Complexes and Exerts Synapse-Specific Inhibition of Neurotransmission in Ex Vivo Hippocampal Slices

Brain sciences, 2021-06, Vol.11 (6), p.787

2021

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Mechanisms of seizure-induced ‘transcriptional channelopathy’ of hyperpolarization-activated cyclic nucleotide gated (HCN) channels

Neurobiology of disease, 2008-02, Vol.29 (2), p.297-305

2008

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Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?

Ketone bodies mediate antiseizure effects through mitochondrial permeability transition

Ketogenic diet treatment increases longevity in Kcna1‐null mice, a model of sudden unexpected death in epilepsy

Ketone Bodies as Anti-Seizure Agents

Altered ventilatory responses to hypercapnia-hypoxia challenges in a preclinical SUDEP model involve orexin neurons

Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy

Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin

Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures

Dietary and Metabolic Approaches for Treating Autism Spectrum Disorders, Affective Disorders and Cognitive Impairment Comorbid with Epilepsy: A Review of Clinical and Preclinical Evidence

Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice

Accumulation of rest deficiency precedes sudden death of epileptic Kv1.1 knockout mice, a model of sudden unexpected death in epilepsy

Pharmacoresponsiveness of spontaneous recurrent seizures and the comorbid sleep disorder of epileptic Kcna1-null mice

Synergistic protection against acute flurothyl‐induced seizures by adjuvant treatment of the ketogenic diet with the type 2 diabetes drug pioglitazone

Ketogenic diet–mediated seizure reduction preserves CA1 cell numbers in epileptic Kcna1‐null mice: An unbiased stereological assessment

Ketogenic diet regulates the antioxidant catalase via the transcription factor PPARγ2

Respiratory dysfunction progresses with age in Kcna1‐null mice, a model of sudden unexpected death in epilepsy

Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices

Adenosine has two faces: Regionally dichotomous adenosine tone in a model of epilepsy with comorbid sleep disorders

Orexin receptors regulate hippocampal sharp wave-ripple complexes in ex vivo slices

Ascorbic Acid Reduces Neurotransmission, Synaptic Plasticity, and Spontaneous Hippocampal Rhythms in In Vitro Slices

Personalization of SUDEP risk: A survey of transient subclinical comorbid changes

Functional MRI Correlates of Carbon Dioxide Chemosensing in Persons With Epilepsy

Ketone bodies are protective against oxidative stress in neocortical neurons

Carbamazepine Reduces Sharp Wave-Ripple Complexes and Exerts Synapse-Specific Inhibition of Neurotransmission in Ex Vivo Hippocampal Slices

Mechanisms of seizure-induced ‘transcriptional channelopathy’ of hyperpolarization-activated cyclic nucleotide gated (HCN) channels

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