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MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study

The lancet oncology, 2017-02, Vol.18 (2), p.192-201

2017

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Intralymphatic allergen administration renders specific immunotherapy faster and safer: A randomized controlled trial

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (46), p.17908-17912

2008

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MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study

The lancet oncology, 2014-05, Vol.15 (6), p.656-666

2014

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A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia

PloS one, 2018-01, Vol.13 (1), p.e0190537-e0190537

2018

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IL-1 Mediates Tissue-Specific Inflammation and Severe Respiratory Failure in COVID-19

Journal of innate immunity, 2022-12, Vol.14 (6), p.643-656

2022

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Interleukin-1 receptor antagonist levels predict favorable outcome after bermekimab, a first-in-class true human interleukin-1α antibody, in a phase III randomized study of advanced colorectal cancer

Oncoimmunology, 2019-03, Vol.8 (3), p.1551651-1551651

2019

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Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin- 2 Receptor β

Science (American Association for the Advancement of Science), 1995-06, Vol.268 (5216), p.1472-1476

1995

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Xilonix, a novel true human antibody targeting the inflammatory cytokine interleukin-1 alpha, in non-small cell lung cancer

Investigational new drugs, 2015-06, Vol.33 (3), p.621-631

2015

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Fibroblasts as Efficient Antigen-Presenting Cells in Lymphoid Organs

Science (American Association for the Advancement of Science), 1995-06, Vol.268 (5215), p.1343-1347

1995

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MABp1 Targeting IL-1α for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: A Randomized Study

Journal of investigative dermatology, 2018-04, Vol.138 (4), p.795-801

2018

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Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

Cell, 1996-02, Vol.84 (4), p.551-562

1996

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A Phase II Open-Label Study of Bermekimab in Patients with Hidradenitis Suppurativa Shows Resolution of Inflammatory Lesions and Pain

Journal of investigative dermatology, 2020-08, Vol.140 (8), p.1538-1545.e2

2020

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CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity

Blood, 1997-09, Vol.90 (6), p.2217-2233

1997

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Moving Beyond Conventional Clinical Trial End Points in Treatment-refractory Metastatic Colorectal Cancer: A Composite Quality-of-life and Symptom Control End Point

Clinical therapeutics, 2017-11, Vol.39 (11), p.2135-2145

2017

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Postischemic Administration of IL-1α Neutralizing Antibody Reduces Brain Damage and Neurological Deficit in Experimental Stroke

Circulation (New York, N.Y.), 2020-07, Vol.142 (2), p.187-189

2020

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CD44 Regulates Hematopoietic Progenitor Distribution, Granuloma Formation, and Tumorigenicity

Blood, 1997-09, Vol.90 (6), p.2217-2233

1997

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On the Role of Antigen in Maintaining Cytotoxic T-Cell Memory

Proceedings of the National Academy of Sciences - PNAS, 1996-09, Vol.93 (18), p.9716-9723

1996

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MABp1 to improve clinical outcomes of patients with symptomatic refractory metastatic colorectal cancer patients: Per-protocol population analysis of phase III study (PT026)

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.3530-3530

2017

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Pre-treatment endogenous interleukin-1 receptor antagonist (IL-1Ra) levels in metastatic colorectal cancer (mCRC) patients are associated with clinical outcomes after anti-interleukin-1a therapy (MABp1)

Annals of oncology, 2017-06, Vol.28, p.iii98-iii99

2017

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MABp1, a first-in-class true human antibody targeting interleukin-1[alpha] in refractory cancers: an open-label, phase 1 dose-escalation and expansion study

The lancet oncology, 2014-05, Vol.15 (6), p.656

2014

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LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor

The Journal of experimental medicine, 1996-04, Vol.183 (4), p.1415-1426

1996

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Abstract A211: A phase I study of MABp1, a first-in-human, first-true human monoclonal antibody against the IL-1 in patients with advanced cancers

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.A211-A211

2011

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Influence of cardiac nerve status on cardiovascular regulation and cardioprotection

World journal of cardiology, 2017-06, Vol.9 (6), p.508-520

2017

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Characterization of the liver-specific component of the cAMP response unit in the phosphoenolpyruvate carboxykinase (GTP) gene promoter

The Journal of biological chemistry, 1994-05, Vol.269 (19), p.14276-14283

1994

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The airplane game: lean accounting takes flight

Management accounting quarterly, 2012-09, Vol.14 (1), p.1

2012

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MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study

Intralymphatic allergen administration renders specific immunotherapy faster and safer: A randomized controlled trial

MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study

A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia

IL-1 Mediates Tissue-Specific Inflammation and Severe Respiratory Failure in COVID-19

Interleukin-1 receptor antagonist levels predict favorable outcome after bermekimab, a first-in-class true human interleukin-1α antibody, in a phase III randomized study of advanced colorectal cancer

Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin- 2 Receptor β

Xilonix, a novel true human antibody targeting the inflammatory cytokine interleukin-1 alpha, in non-small cell lung cancer

Fibroblasts as Efficient Antigen-Presenting Cells in Lymphoid Organs

MABp1 Targeting IL-1α for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: A Randomized Study

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

A Phase II Open-Label Study of Bermekimab in Patients with Hidradenitis Suppurativa Shows Resolution of Inflammatory Lesions and Pain

CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity

Moving Beyond Conventional Clinical Trial End Points in Treatment-refractory Metastatic Colorectal Cancer: A Composite Quality-of-life and Symptom Control End Point

Postischemic Administration of IL-1α Neutralizing Antibody Reduces Brain Damage and Neurological Deficit in Experimental Stroke

CD44 Regulates Hematopoietic Progenitor Distribution, Granuloma Formation, and Tumorigenicity

On the Role of Antigen in Maintaining Cytotoxic T-Cell Memory

MABp1 to improve clinical outcomes of patients with symptomatic refractory metastatic colorectal cancer patients: Per-protocol population analysis of phase III study (PT026)

Pre-treatment endogenous interleukin-1 receptor antagonist (IL-1Ra) levels in metastatic colorectal cancer (mCRC) patients are associated with clinical outcomes after anti-interleukin-1a therapy (MABp1)

MABp1, a first-in-class true human antibody targeting interleukin-1[alpha] in refractory cancers: an open-label, phase 1 dose-escalation and expansion study

LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor

Abstract A211: A phase I study of MABp1, a first-in-human, first-true human monoclonal antibody against the IL-1 in patients with advanced cancers

Influence of cardiac nerve status on cardiovascular regulation and cardioprotection

Characterization of the liver-specific component of the cAMP response unit in the phosphoenolpyruvate carboxykinase (GTP) gene promoter

The airplane game: lean accounting takes flight

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