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The diverse mechanisms and anticancer potential of naphthoquinones

Cancer cell international, 2019-08, Vol.19 (1), p.207-207, Article 207

2019

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Insights into cytochrome bc1 complex binding mode of antimalarial 2-hydroxy-1,4-naphthoquinones through molecular modelling

Memórias do Instituto Oswaldo Cruz, 2017-04, Vol.112 (4), p.299-308

2017

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Natural products targeting into cancer hallmarks: An update on caffeine, theobromine, and (+)-catechin

Critical reviews in food science and nutrition, 2022-09, Vol.62 (26), p.7222-7241

2022

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N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis

Memórias do Instituto Oswaldo Cruz, 2017-02, Vol.112 (2), p.146-154

2017

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Recent Advances on Targeting Proteases for Antiviral Development

Viruses, 2024-02, Vol.16 (3), p.366

2024

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Past and future of trypanosomatids high-throughput phenotypic screening

Memórias do Instituto Oswaldo Cruz, 2022-01, Vol.117, p.e210402

2022

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Proteomic and bioinformatic analysis of Trypanosoma cruzi chemotherapy and potential drug targets: new pieces for an old puzzle

Current drug targets, 2014-03, Vol.15 (3), p.255-271

2014

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Synthesis and evaluation of the cytotoxic activity of 1,2-furanonaphthoquinones tethered to 1,2,3-1H-triazoles in myeloid and lymphoid leukemia cell lines

European journal of medicinal chemistry, 2014-09, Vol.84, p.708-717

2014

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Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni

Scientific reports, 2024-01, Vol.14 (1), p.1582-1582, Article 1582

2024

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Kinetics Studies on the Inhibition Mechanism of Pancreatic α-Amylase by Glycoconjugated 1H-1,2,3-Triazoles: A New Class of Inhibitors with Hypoglycemiant Activity

Chembiochem : a European journal of chemical biology, 2012-07, Vol.13 (11), p.1584-1593

2012

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FindTargetsWEB: A User-Friendly Tool for Identification of Potential Therapeutic Targets in Metabolic Networks of Bacteria

Frontiers in genetics, 2019-07, Vol.10, p.633-633

2019

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Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling

MedChemComm, 2019-12, Vol.1 (12), p.289-211

2019

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Increased tau phosphorylation and receptor for advanced glycation endproducts (RAGE) in the brain of mice infected with Leishmania amazonensis

Brain, behavior, and immunity, 2015-01, Vol.43, p.37-45

2015

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Combating Neglected Diseases in the Post-COVID-19 World

Revista Virtual de Química, 2021, Vol.13 (2), p.308-309

Paes Silva-Jr, Floriano

2021

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In silico Strategies to Support Fragment-to-Lead Optimization in Drug Discovery

Frontiers in chemistry, 2020-02, Vol.8, p.93

2020

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1-Phenyl-1H- and 2-phenyl-2H-1,2,3-triazol derivatives: Design, synthesis and inhibitory effect on alpha-glycosidases

European journal of medicinal chemistry, 2014-03, Vol.74, p.461-476

2014

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Influence of temperature for the azide displacement in benzodiazepine derivatives: Experimental and DFT study of competing SN1, SN2 and double SN2 reaction pathways

Tetrahedron letters, 2021-03, Vol.68, p.152937, Article 152937

2021

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Design, synthesis, cholinesterase inhibition and molecular modelling study of novel tacrine hybrids with carbohydrate derivatives

Bioorganic & medicinal chemistry, 2018-11, Vol.26 (20), p.5566-5577

2018

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Schistosoma mansoni infection causes oxidative stress and alters receptor for advanced glycation endproduct (RAGE) and tau levels in multiple organs in mice

International journal for parasitology, 2013-04, Vol.43 (5), p.371-379

2013

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FioSchisto's expert perspective on implementing WHO guidelines for schistosomiasis control and transmission elimination in Brazil

Frontiers in immunology, 2023, Vol.14, p.1268998-1268998

2023

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Synthesis of new lophine–carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling† †Electronic supplementary information (ESI) available: Graphics and extra data of in vitro and in silico experiments and detailed spectroscopic characterization. See DOI: 10.1039/c9md00358d

MedChemComm, 2019-11, Vol.10 (12), p.2089-2101

2019

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New insights in Trypanosoma cruzi proteomic map: further post-translational modifications and potential drug targets in Y strain epimastigotes

Journal of integrated OMICS, 2012-12, Vol.2 (2)

2012

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The diverse mechanisms and anticancer potential of naphthoquinones

Insights into cytochrome bc1 complex binding mode of antimalarial 2-hydroxy-1,4-naphthoquinones through molecular modelling

Natural products targeting into cancer hallmarks: An update on caffeine, theobromine, and (+)-catechin

N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis

Recent Advances on Targeting Proteases for Antiviral Development

Past and future of trypanosomatids high-throughput phenotypic screening

Proteomic and bioinformatic analysis of Trypanosoma cruzi chemotherapy and potential drug targets: new pieces for an old puzzle

Synthesis and evaluation of the cytotoxic activity of 1,2-furanonaphthoquinones tethered to 1,2,3-1H-triazoles in myeloid and lymphoid leukemia cell lines

Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni

Kinetics Studies on the Inhibition Mechanism of Pancreatic α-Amylase by Glycoconjugated 1H-1,2,3-Triazoles: A New Class of Inhibitors with Hypoglycemiant Activity

FindTargetsWEB: A User-Friendly Tool for Identification of Potential Therapeutic Targets in Metabolic Networks of Bacteria

Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling

Increased tau phosphorylation and receptor for advanced glycation endproducts (RAGE) in the brain of mice infected with Leishmania amazonensis

Combating Neglected Diseases in the Post-COVID-19 World

In silico Strategies to Support Fragment-to-Lead Optimization in Drug Discovery

1-Phenyl-1H- and 2-phenyl-2H-1,2,3-triazol derivatives: Design, synthesis and inhibitory effect on alpha-glycosidases

Influence of temperature for the azide displacement in benzodiazepine derivatives: Experimental and DFT study of competing SN1, SN2 and double SN2 reaction pathways

Design, synthesis, cholinesterase inhibition and molecular modelling study of novel tacrine hybrids with carbohydrate derivatives

Schistosoma mansoni infection causes oxidative stress and alters receptor for advanced glycation endproduct (RAGE) and tau levels in multiple organs in mice

FioSchisto's expert perspective on implementing WHO guidelines for schistosomiasis control and transmission elimination in Brazil

New insights in Trypanosoma cruzi proteomic map: further post-translational modifications and potential drug targets in Y strain epimastigotes

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