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Conformations of voltage-sensing domain III differentially define NaV channel closed- and open-state inactivation

The Journal of general physiology, 2021-09, Vol.153 (9), p.1

2021

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Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (32), p.13180-13185

2013

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Development of a Mixed Reality Platform for Lateral Skull Base Anatomy

Otology & neurotology, 2018-12, Vol.39 (10), p.e1137-e1142

2018

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Molecular Pathology of Sodium Channel Beta-Subunit Variants

Frontiers in pharmacology, 2021-11, Vol.12, p.761275-761275

2021

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An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening

Nature communications, 2022-11, Vol.13 (1), p.1-13, Article 6784

2022

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Identification of structures for ion channel kinetic models

PLoS computational biology, 2021-08, Vol.17 (8), p.e1008932-e1008932

2021

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Depolarization of the conductance-voltage relationship in the NaV1.5 mutant, E1784K, is due to altered fast inactivation

PloS one, 2017-09, Vol.12 (9), p.e0184605-e0184605

2017

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Computational biology in the study of cardiac ion channels and cell electrophysiology

Quarterly reviews of biophysics, 2006-02, Vol.39 (1), p.57-116

2006

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Intrinsic mechanisms in the gating of resurgent Na + currents

eLife, 2022-01, Vol.11

2022

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Regulation of Na + channel inactivation by the DIII and DIV voltage-sensing domains

The Journal of general physiology, 2017-03, Vol.149 (3), p.389-403

2017

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Pulsus Alternans in Cardiogenic Shock Recapitulated in Single Cell Fluorescence Imaging of a Patient's Cardiomyocyte

Circulation. Heart failure, 2022-02, Vol.15 (2), p.e008855-e008855

2022

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Modeling K,ATP-Dependent Excitability in Pancreatic Islets

Biophysical journal, 2014-11, Vol.107 (9), p.2016-2026

2014

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Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening

Science advances, 2020-12, Vol.6 (50)

2020

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Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (50), p.15366-15371

2015

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Registration Techniques for Clinical Applications of Three-Dimensional Augmented Reality Devices

IEEE journal of translational engineering in health and medicine, 2021-01, Vol.9, p.1-14

2021

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multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (27), p.11102-11106

2009

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Performance Evaluation of Mixed Reality Display for Guidance During Transcatheter Cardiac Mapping and Ablation

IEEE journal of translational engineering in health and medicine, 2020-01, Vol.8, p.1-10

2020

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Direct Measurement of Cardiac Na+ Channel Conformations Reveals Molecular Pathologies of Inherited Mutations

Circulation. Arrhythmia and electrophysiology, 2015-10, Vol.8 (5), p.1228-1239

2015

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Use of extended realities in cardiology

Trends in cardiovascular medicine, 2020-04, Vol.30 (3), p.143-148

2020

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How to Connect Cardiac Excitation to the Atomic Interactions of Ion Channels

Biophysical journal, 2018-01, Vol.114 (2), p.259-266

Silva, Jonathan R.

2018

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Early preclinical experience of a mixed reality ultrasound system with active GUIDance for NEedle-based interventions: The GUIDE study

Cardiovascular digital health journal, 2022-10, Vol.3 (5), p.232-240

2022

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Predicting patient-specific single-cell parameters in computational cardiac models using machine learning

Biophysical journal, 2023-02, Vol.122 (3), p.381a-381a

2023

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Reversible Photothermal Modulation of Electrical Activity of Excitable Cells using Polydopamine Nanoparticles

Advanced materials (Weinheim), 2021-08, Vol.33 (32), p.e2008809-n/a

2021

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Modulation of the effects of class Ib antiarrhythmics on cardiac NaV1.5-encoded channels by accessory NaVβ subunits

JCI insight, 2021-08, Vol.6 (15)

2021

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A Molecularly Detailed NaV1.5 Model Reveals a New Class I Antiarrhythmic Target

JACC. Basic to translational science, 2019-10, Vol.4 (6), p.736-751

2019

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Conformations of voltage-sensing domain III differentially define NaV channel closed- and open-state inactivation

Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening

Development of a Mixed Reality Platform for Lateral Skull Base Anatomy

Molecular Pathology of Sodium Channel Beta-Subunit Variants

An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening

Identification of structures for ion channel kinetic models

Depolarization of the conductance-voltage relationship in the NaV1.5 mutant, E1784K, is due to altered fast inactivation

Computational biology in the study of cardiac ion channels and cell electrophysiology

Intrinsic mechanisms in the gating of resurgent Na + currents

Regulation of Na + channel inactivation by the DIII and DIV voltage-sensing domains

Pulsus Alternans in Cardiogenic Shock Recapitulated in Single Cell Fluorescence Imaging of a Patient's Cardiomyocyte

Modeling K,ATP-Dependent Excitability in Pancreatic Islets

Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening

Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel

Registration Techniques for Clinical Applications of Three-Dimensional Augmented Reality Devices

multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential

Performance Evaluation of Mixed Reality Display for Guidance During Transcatheter Cardiac Mapping and Ablation

Direct Measurement of Cardiac Na+ Channel Conformations Reveals Molecular Pathologies of Inherited Mutations

Use of extended realities in cardiology

How to Connect Cardiac Excitation to the Atomic Interactions of Ion Channels

Early preclinical experience of a mixed reality ultrasound system with active GUIDance for NEedle-based interventions: The GUIDE study

Predicting patient-specific single-cell parameters in computational cardiac models using machine learning

Reversible Photothermal Modulation of Electrical Activity of Excitable Cells using Polydopamine Nanoparticles

Modulation of the effects of class Ib antiarrhythmics on cardiac NaV1.5-encoded channels by accessory NaVβ subunits

A Molecularly Detailed NaV1.5 Model Reveals a New Class I Antiarrhythmic Target

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