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Oral Cholesteryl Ester Transfer Protein (CETP) Inhibitors: A Potential New Approach for Treating Coronary Artery Disease

Journal of medicinal chemistry, 2006-01, Vol.49 (1), p.1-22

Sikorski, James A

2006

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Application of vinylogous carbamates and vinylogous aminonitriles to the regiospecific synthesis of uniquely functionalized pyrroles and quinolones

Tetrahedron, 2018-12, Vol.74 (52), p.7408-7420

2018

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Bio-active engineered 50 nm silica nanoparticles with bone anabolic activity: therapeutic index, effective concentration, and cytotoxicity profile in vitro

Toxicology in vitro, 2014-04, Vol.28 (3), p.354-364

2014

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Further studies on the application of vinylogous amides and β-halovinylaldehydes to the regiospecific synthesis of unsymmetrical, polyfunctionalized 2,3,4- and 1,2,3,4- substituted pyrroles

Tetrahedron, 2018-05, Vol.74 (21), p.2650-2663

2018

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Recent advances in therapeutic chalcones

Expert opinion on therapeutic patents, 2004-12, Vol.14 (12), p.1669-1691

2004

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Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based Design

Molecular pharmacology, 2016-02, Vol.89 (2), p.287-296

2016

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Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities

Bioorganic & medicinal chemistry, 2017-06, Vol.25 (12), p.3206-3214

2017

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The application of vinylogous iminium salt derivatives to the synthesis of Ningalin B hexamethyl ether

Tetrahedron, 2003-01, Vol.59 (2), p.207-215

2003

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A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats

Science (American Association for the Advancement of Science), 1999-10, Vol.286 (5438), p.304-306

1999

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AGIX-4207 [2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid], a novel antioxidant and anti-inflammatory compound: cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression

The Journal of pharmacology and experimental therapeutics, 2005-05, Vol.313 (2), p.492

2005

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Carboxylated, Heteroaryl-Substituted Chalcones as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1304-1315

2007

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Cholesteryl ester transfer protein inhibitors as potential new therapies for coronary artery disease

Expert opinion on therapeutic patents, 2006-06, Vol.16 (6), p.753-772

Sikorski, James A

2006

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Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease

Bioorganic & medicinal chemistry, 2003-11, Vol.11 (22), p.4769-4777

2003

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Design and Syntheses of Potent and Selective Dipeptide Inhibitors of Candida albicans Myristoyl-CoA:Protein N-Myristoyltransferase

Journal of medicinal chemistry, 1995-05, Vol.38 (11), p.1837-1840

1995

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The application of vinylogous iminium salt derivatives and microwave accelerated Vilsmeier–Haack reactions to efficient relay syntheses of the polycitone and storniamide natural products

Tetrahedron, 2008-01, Vol.64 (22), p.5246-5253

2008

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Understanding Glyphosate's Molecular Mode of Action with EPSP Synthase: Evidence Favoring an Allosteric Inhibitor Model

Accounts of chemical research, 1997-01, Vol.30 (1), p.2-8

1997

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Discovery of a Simple Picomolar Inhibitor of Cholesteryl Ester Transfer Protein

Journal of medicinal chemistry, 2003-05, Vol.46 (11), p.2152-2168

2003

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Application of 2-substituted vinamidinium salts to the synthesis of 2,4-disubstituted pyrroles

Journal of organic chemistry, 1990-07, Vol.55 (15), p.4735-4740

1990

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Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2545-2548

2002

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Bio-active engineered 50nm silica nanoparticles with bone anabolic activity: Therapeutic index, effective concentration, and cytotoxicity profile in vitro

Toxicology in vitro, 2014-04, Vol.28 (3), p.354-364

2014

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Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (13), p.1625-1628

2001

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An efficient, regiocontrolled synthesis of 5-aryl-2-carbethoxypyrroles from 3-aryl-3-chloropropeniminium salts

Journal of organic chemistry, 1992-09, Vol.57 (20), p.5480-5483

1992

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Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-α-induced VCAM-1 expression

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (6), p.1513-1517

2004

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The application of vinylogous iminium salt derivatives to a regiocontrolled and efficient relay synthesis of lukianol a and related marine natural products

Tetrahedron, 1999-12, Vol.55 (51), p.14515-14522

1999

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Chiral N,N-Disubstituted Trifluoro-3-Amino-2-Propanols Are Potent Inhibitors of Cholesteryl Ester Transfer Protein

Journal of medicinal chemistry, 2002-08, Vol.45 (18), p.3891-3904

2002

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Oral Cholesteryl Ester Transfer Protein (CETP) Inhibitors: A Potential New Approach for Treating Coronary Artery Disease

Application of vinylogous carbamates and vinylogous aminonitriles to the regiospecific synthesis of uniquely functionalized pyrroles and quinolones

Bio-active engineered 50 nm silica nanoparticles with bone anabolic activity: therapeutic index, effective concentration, and cytotoxicity profile in vitro

Further studies on the application of vinylogous amides and β-halovinylaldehydes to the regiospecific synthesis of unsymmetrical, polyfunctionalized 2,3,4- and 1,2,3,4- substituted pyrroles

Recent advances in therapeutic chalcones

Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based Design

Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities

The application of vinylogous iminium salt derivatives to the synthesis of Ningalin B hexamethyl ether

A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats

Carboxylated, Heteroaryl-Substituted Chalcones as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases

Cholesteryl ester transfer protein inhibitors as potential new therapies for coronary artery disease

Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease

Design and Syntheses of Potent and Selective Dipeptide Inhibitors of Candida albicans Myristoyl-CoA:Protein N-Myristoyltransferase

The application of vinylogous iminium salt derivatives and microwave accelerated Vilsmeier–Haack reactions to efficient relay syntheses of the polycitone and storniamide natural products

Understanding Glyphosate's Molecular Mode of Action with EPSP Synthase: Evidence Favoring an Allosteric Inhibitor Model

Discovery of a Simple Picomolar Inhibitor of Cholesteryl Ester Transfer Protein

Application of 2-substituted vinamidinium salts to the synthesis of 2,4-disubstituted pyrroles

Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis

Bio-active engineered 50nm silica nanoparticles with bone anabolic activity: Therapeutic index, effective concentration, and cytotoxicity profile in vitro

Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein

An efficient, regiocontrolled synthesis of 5-aryl-2-carbethoxypyrroles from 3-aryl-3-chloropropeniminium salts

Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-α-induced VCAM-1 expression

The application of vinylogous iminium salt derivatives to a regiocontrolled and efficient relay synthesis of lukianol a and related marine natural products

Chiral N,N-Disubstituted Trifluoro-3-Amino-2-Propanols Are Potent Inhibitors of Cholesteryl Ester Transfer Protein

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