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Molecular Pathways: Regulation and Therapeutic Implications of Multidrug Resistance

Clinical cancer research, 2012-04, Vol.18 (7), p.1863-1869

2012

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Single Gene Prognostic Biomarkers in Ovarian Cancer: A Meta-Analysis

PloS one, 2016-02, Vol.11 (2), p.e0149183-e0149183

2016

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A clinical trial of zosuquidar plus gemtuzumab ozogamicin (GO) in relapsed or refractory acute myeloid leukemia (RR AML): evidence of efficacy based on leukemic blast P-glycoprotein functional phenotype

Cancer chemotherapy and pharmacology, 2023-11, Vol.92 (5), p.369-380

2023

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The Syk inhibitor R406 is a modulator of P-glycoprotein (ABCB1)-mediated multidrug resistance

PloS one, 2019-01, Vol.14 (1), p.e0210879-e0210879

2019

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The miR-200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR-3 and MES-OV cells

Molecular oncology, 2015-10, Vol.9 (8), p.1678-1693

2015

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Mechanisms of resistance to cabazitaxel

Molecular cancer therapeutics, 2015-01, Vol.14 (1), p.193-201

2015

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Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein

Cancer chemotherapy and pharmacology, 2018-06, Vol.81 (6), p.1095-1103

2018

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A network model of a cooperative genetic landscape in brain tumors

JAMA : the journal of the American Medical Association, 2009-07, Vol.302 (3), p.261

2009

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Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas

Cancer research (Chicago, Ill.), 2005-10, Vol.65 (19), p.8679-8689

2005

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Safety, tolerability and efficacy of agonist anti-CD27 antibody (varlilumab) administered in combination with anti-PD-1 (nivolumab) in advanced solid tumors

Journal for immunotherapy of cancer, 2022-08, Vol.10 (8), p.e005147

2022

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Identification of ovarian cancer driver genes by using module network integration of multi-omics data

Interface focus, 2013-08, Vol.3 (4), p.20130013-20130013

2013

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High-resolution genome-wide mapping of genetic alterations in human glial brain tumors

Cancer research (Chicago, Ill.), 2005-05, Vol.65 (10), p.4088-4096

2005

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First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers

Journal of clinical oncology, 2019-04, Vol.37 (12), p.946-953

2019

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Differential Gene Expression Patterns and Interaction Networks in BCR-ABL–Positive and –Negative Adult Acute Lymphoblastic Leukemias

Journal of clinical oncology, 2007-04, Vol.25 (11), p.1341-1349

2007

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Mitoxantrone, Etoposide, and Cytarabine With or Without Valspodar in Patients With Relapsed or Refractory Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome: A Phase III Trial (E2995)

Journal of clinical oncology, 2004-03, Vol.22 (6), p.1078-1086

2004

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Continuous 72-h infusion of zosuquidar with chemotherapy in patients with newly diagnosed acute myeloid leukemia stratified for leukemic blast P-glycoprotein phenotype

Cancer chemotherapy and pharmacology, 2024-06, Vol.93 (6), p.595-604

2024

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Expression and silencing of the microtubule-associated protein Tau in breast cancer cells

Molecular cancer therapeutics, 2010-11, Vol.9 (11), p.2970-2981

2010

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A Phase II Study of Gefitinib, 5-Fluorouracil, Leucovorin, and Oxaliplatin in Previously Untreated Patients with Metastatic Colorectal Cancer

Clinical cancer research, 2008-11, Vol.14 (21), p.7074-7079

2008

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Phase II Study of Gefitinib, Fluorouracil, Leucovorin, and Oxaliplatin Therapy in Previously Treated Patients With Metastatic Colorectal Cancer

Journal of clinical oncology, 2005-08, Vol.23 (24), p.5613-5619

2005

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Analysis of Phase II Studies on Targeted Agents and Subsequent Phase III Trials: What Are the Predictors for Success?

Journal of clinical oncology, 2008-03, Vol.26 (9), p.1511-1518

2008

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Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchymal transition

British journal of cancer, 2017-05, Vol.116 (10), p.1318-1328

2017

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Safety and Activity of Varlilumab, a Novel and First-in-Class Agonist Anti-CD27 Antibody, in Patients With Advanced Solid Tumors

Journal of clinical oncology, 2017-06, Vol.35 (18), p.2028-2036

2017

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Gene Expression Profiling Differentiates Germ Cell Tumors from Other Cancers and Defines Subtype-Specific Signatures

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (49), p.17763-17768

2005

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Carboplatin-induced upregulation of pan β-tubulin and class III β-tubulin is implicated in acquired resistance and cross-resistance of ovarian cancer

Cellular and molecular life sciences : CMLS, 2023-10, Vol.80 (10), p.294, Article 294

2023

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Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers

Molecular oncology, 2014-10, Vol.8 (7), p.1231-1239

2014

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Molecular Pathways: Regulation and Therapeutic Implications of Multidrug Resistance

Single Gene Prognostic Biomarkers in Ovarian Cancer: A Meta-Analysis

A clinical trial of zosuquidar plus gemtuzumab ozogamicin (GO) in relapsed or refractory acute myeloid leukemia (RR AML): evidence of efficacy based on leukemic blast P-glycoprotein functional phenotype

The Syk inhibitor R406 is a modulator of P-glycoprotein (ABCB1)-mediated multidrug resistance

The miR-200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR-3 and MES-OV cells

Mechanisms of resistance to cabazitaxel

Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein

A network model of a cooperative genetic landscape in brain tumors

Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas

Safety, tolerability and efficacy of agonist anti-CD27 antibody (varlilumab) administered in combination with anti-PD-1 (nivolumab) in advanced solid tumors

Identification of ovarian cancer driver genes by using module network integration of multi-omics data

High-resolution genome-wide mapping of genetic alterations in human glial brain tumors

First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers

Differential Gene Expression Patterns and Interaction Networks in BCR-ABL–Positive and –Negative Adult Acute Lymphoblastic Leukemias

Mitoxantrone, Etoposide, and Cytarabine With or Without Valspodar in Patients With Relapsed or Refractory Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome: A Phase III Trial (E2995)

Continuous 72-h infusion of zosuquidar with chemotherapy in patients with newly diagnosed acute myeloid leukemia stratified for leukemic blast P-glycoprotein phenotype

Expression and silencing of the microtubule-associated protein Tau in breast cancer cells

A Phase II Study of Gefitinib, 5-Fluorouracil, Leucovorin, and Oxaliplatin in Previously Untreated Patients with Metastatic Colorectal Cancer

Phase II Study of Gefitinib, Fluorouracil, Leucovorin, and Oxaliplatin Therapy in Previously Treated Patients With Metastatic Colorectal Cancer

Analysis of Phase II Studies on Targeted Agents and Subsequent Phase III Trials: What Are the Predictors for Success?

Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchymal transition

Safety and Activity of Varlilumab, a Novel and First-in-Class Agonist Anti-CD27 Antibody, in Patients With Advanced Solid Tumors

Gene Expression Profiling Differentiates Germ Cell Tumors from Other Cancers and Defines Subtype-Specific Signatures

Carboplatin-induced upregulation of pan β-tubulin and class III β-tubulin is implicated in acquired resistance and cross-resistance of ovarian cancer

Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers

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