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A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

Nature cell biology, 2012-03, Vol.14 (3), p.318

2012

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Vigilance and Validation: Keys to Success in RNAi Screening

ACS chemical biology, 2011-01, Vol.6 (1), p.47-60

2011

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USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin

Nature communications, 2019-09, Vol.10 (1), p.4184-14, Article 4184

2019

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Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C

Nature (London), 2014-10, Vol.514 (7524), p.646-649

2014

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A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

Nature methods, 2012-04, Vol.9 (4), p.363

2012

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Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites

Nature communications, 2022-02, Vol.13 (1), p.930-930, Article 930

2022

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Engineering digitizer circuits for chemical and genetic screens in human cells

Nature communications, 2021-10, Vol.12 (1), p.6150-6150, Article 6150

2021

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Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

Cancer cell, 2010-10, Vol.18 (4), p.382-395

2010

Volltextzugriff (PDF)

A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production

Cell reports (Cambridge), 2019-12, Vol.29 (10), p.2970-2978.e6

2019

Volltextzugriff (PDF)

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

Nature chemical biology, 2020-01, Vol.16 (1), p.50

2020

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Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma

Molecular cancer research, 2019-01, Vol.17 (1), p.199-211

2019

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Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

eLife, 2019-11, Vol.8

2019

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DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

Nature communications, 2024-01, Vol.15 (1), p.275-19, Article 275

2024

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The G2/M Regulator Histone Demethylase PHF8 Is Targeted for Degradation by the Anaphase-Promoting Complex Containing CDC20

Molecular and Cellular Biology, 2013-11, Vol.33 (21), p.4166-4180

2013

Volltextzugriff (PDF)

DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery

ACS chemical biology, 2022-06, Vol.17 (6), p.1401-1414

2022

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Benchmarking network algorithms for contextualizing genes of interest

PLoS computational biology, 2019-12, Vol.15 (12), p.e1007403

2019

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Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control

Cell reports (Cambridge), 2023-09, Vol.42 (9), p.113056-113056, Article 113056

2023

Volltextzugriff (PDF)

Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

Nature communications, 2024-08, Vol.15 (1), p.7109-5

2024

Volltextzugriff (PDF)

Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control

Cell reports (Cambridge), 2023-09, Vol.42 (9), p.113159, Article 113159

2023

Volltextzugriff (PDF)

A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies

PloS one, 2011-09, Vol.6 (9), p.e25511-e25511

2011

Volltextzugriff (PDF)

Cell Cycle-dependent Regulation of Pyrimidine Biosynthesis

The Journal of biological chemistry, 2003-01, Vol.278 (5), p.3403-3409

2003

Volltextzugriff (PDF)

Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results

Cell systems, 2017-02, Vol.4 (2), p.182-193.e4

2017

Volltextzugriff (PDF)

Nuclear Localization and Mitogen-activated Protein Kinase Phosphorylation of the Multifunctional Protein CAD

The Journal of biological chemistry, 2005-07, Vol.280 (27), p.25611-25620

2005

Volltextzugriff (PDF)

Protein kinase C modulates the up-regulation of the pyrimidine biosynthetic complex, CAD, by MAP kinase

Frontiers in bioscience, 2007-05, Vol.12, p.3892

2007

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A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

Vigilance and Validation: Keys to Success in RNAi Screening

USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin

Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C

A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites

Engineering digitizer circuits for chemical and genetic screens in human cells

Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

The G2/M Regulator Histone Demethylase PHF8 Is Targeted for Degradation by the Anaphase-Promoting Complex Containing CDC20

DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery

Benchmarking network algorithms for contextualizing genes of interest

Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control

Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical MatterCompounds with Novel Mechanisms from High-Throughput Screening Profiles

Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control

A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies

Cell Cycle-dependent Regulation of Pyrimidine Biosynthesis

Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results

Nuclear Localization and Mitogen-activated Protein Kinase Phosphorylation of the Multifunctional Protein CAD

Protein kinase C modulates the up-regulation of the pyrimidine biosynthetic complex, CAD, by MAP kinase

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