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Infectious Entry and Neutralization of Pathogenic JC Polyomaviruses

Cell reports (Cambridge), 2017-10, Vol.21 (5), p.1169-1179

2017

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Molecular Basis for Failure of “Atypical” C1 Domain of Vav1 to Bind Diacylglycerol/Phorbol Ester

The Journal of biological chemistry, 2012-04, Vol.287 (16), p.13137-13158

2012

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Materials from peptide assembly: towards the treatment of cancer and transmittable disease

Current opinion in chemical biology, 2011-06, Vol.15 (3), p.427-434

2011

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Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.190-197

2016

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Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain

Cancer biology & therapy, 2020-03, Vol.21 (3), p.223-230

2020

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Rational Design of Drugs That Induce Human Immunodeficiency Virus Replication

Journal of Virology, 2003-10, Vol.77 (19), p.10227-10236

2003

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North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity

ChemMedChem, 2009-08, Vol.4 (8), p.1354-1363

2009

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Diacylglycerol Lactones Targeting the Structural Features That Distinguish the Atypical C1 Domains of Protein Kinase C ζ and ι from Typical C1 Domains

Journal of medicinal chemistry, 2014-05, Vol.57 (9), p.3835-3844

2014

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Carbene−Alkyne−Alkene Cyclization Reactions

Chemical reviews, 1996-01, Vol.96 (1), p.271-288

1996

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Differential Binding Modes of Diacylglycerol (DAG) and DAG Lactones to Protein Kinase C (PK-C)

Journal of medicinal chemistry, 2003-04, Vol.46 (9), p.1571-1579

2003

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Conformationally Constrained Analogues of Diacylglycerol. 29. Cells Sort Diacylglycerol-Lactone Chemical Zip Codes to Produce Diverse and Selective Biological Activities

Journal of medicinal chemistry, 2008-09, Vol.51 (17), p.5198-5220

2008

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N-Methyl-Substituted Fluorescent DAG-Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity

Chembiochem : a European journal of chemical biology, 2011-10, Vol.12 (15), p.2331-2340

2011

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Ceramides: Branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency

Bioorganic & medicinal chemistry, 2009-02, Vol.17 (4), p.1498-1505

2009

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Conformationally Constrained Analogues of Diacylglycerol (DAG). 27. Modulation of Membrane Translocation of Protein Kinase C (PKC) Isozymes α and δ by Diacylglycerol Lactones (DAG-lactones) Containing Rigid-Rod Acyl Groups

Journal of medicinal chemistry, 2007-03, Vol.50 (5), p.962-978

2007

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Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities

Chembiochem : a European journal of chemical biology, 2010-09, Vol.11 (14), p.2003-2009

2010

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Synthesis of Cyclopropylpyrrolidines via Reaction of N-Allyl-N-propargylamides with a Molybdenum Carbene Complex. Effect of Substituents and Reaction Conditions

Journal of organic chemistry, 1996-04, Vol.61 (7), p.2268-2272

1996

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Conformationally Constrained Analogues of Diacylglycerol. 24. Asymmetric Synthesis of a Chiral (R)-DAG-Lactone Template as a Versatile Precursor for Highly Functionalized DAG-Lactones

Organic letters, 2004-07, Vol.6 (14), p.2413-2416

2004

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Conformationally Constrained Analogues of Diacylglycerol (DAG). 28. DAG-dioxolanones Reveal a New Additional Interaction Site in the C1b Domain of PKCδ

Journal of medicinal chemistry, 2007-07, Vol.50 (15), p.3465-3481

2007

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Conformationally Constrained Analogues of Diacylglycerol. 26. Exploring the Chemical Space Surrounding the C1 Domain of Protein Kinase C with DAG-Lactones Containing Aryl Groups at the sn-1 and sn-2 Positions

Journal of medicinal chemistry, 2006-06, Vol.49 (11), p.3185-3203

2006

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Conformationally Constrained Analogues of Diacylglycerol. 21. A Solid-Phase Method of Synthesis of Diacylglycerol Lactones as a Prelude to a Combinatorial Approach for the Synthesis of Protein Kinase C Isozyme-Specific Ligands

Journal of medicinal chemistry, 2004-06, Vol.47 (12), p.3248-3254

2004

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Conformationally Constrained Analogues of Diacylglycerol (DAG). 23 † . Hydrophobic Ligand−Protein Interactions versus Ligand−Lipid Interactions of DAG-Lactones with Protein Kinase C (PK-C)

Journal of medicinal chemistry, 2004-09, Vol.47 (20), p.4858-4864

2004

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Conformationally Constrained Analogues of Diacylglycerol. 20. The Search for an Elusive Binding Site on Protein Kinase C through Relocation of the Carbonyl Pharmacophore Along the sn-1 Side Chain of 1,2-Diacylglycerol Lactones

Journal of medicinal chemistry, 2004-01, Vol.47 (3), p.644-655

2004

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An Optimized Protein Kinase C Activating Diacylglycerol Combining High Binding Affinity (K i) with Reduced Lipophilicity (log P)

Journal of medicinal chemistry, 2001-06, Vol.44 (12), p.1892-1904

2001

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Inside Cover: Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities (ChemBioChem 14/2010)

Chembiochem : a European journal of chemical biology, 2010-09, Vol.11 (14), p.1926-1926

2010

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North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity (ChemMedChem 8/2009)

ChemMedChem, 2009-08, Vol.4 (8), p.1210-1210

2009

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Infectious Entry and Neutralization of Pathogenic JC Polyomaviruses

Molecular Basis for Failure of “Atypical” C1 Domain of Vav1 to Bind Diacylglycerol/Phorbol Ester

Materials from peptide assembly: towards the treatment of cancer and transmittable disease

Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors

Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain

Rational Design of Drugs That Induce Human Immunodeficiency Virus Replication

North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity

Diacylglycerol Lactones Targeting the Structural Features That Distinguish the Atypical C1 Domains of Protein Kinase C ζ and ι from Typical C1 Domains

Carbene−Alkyne−Alkene Cyclization Reactions

Differential Binding Modes of Diacylglycerol (DAG) and DAG Lactones to Protein Kinase C (PK-C)

Conformationally Constrained Analogues of Diacylglycerol. 29. Cells Sort Diacylglycerol-Lactone Chemical Zip Codes to Produce Diverse and Selective Biological Activities

N-Methyl-Substituted Fluorescent DAG-Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity

Ceramides: Branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency

Conformationally Constrained Analogues of Diacylglycerol (DAG). 27. Modulation of Membrane Translocation of Protein Kinase C (PKC) Isozymes α and δ by Diacylglycerol Lactones (DAG-lactones) Containing Rigid-Rod Acyl Groups

Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities

Synthesis of Cyclopropylpyrrolidines via Reaction of N-Allyl-N-propargylamides with a Molybdenum Carbene Complex. Effect of Substituents and Reaction Conditions

Conformationally Constrained Analogues of Diacylglycerol. 24. Asymmetric Synthesis of a Chiral (R)-DAG-Lactone Template as a Versatile Precursor for Highly Functionalized DAG-Lactones

Conformationally Constrained Analogues of Diacylglycerol (DAG). 28. DAG-dioxolanones Reveal a New Additional Interaction Site in the C1b Domain of PKCδ

Conformationally Constrained Analogues of Diacylglycerol. 26. Exploring the Chemical Space Surrounding the C1 Domain of Protein Kinase C with DAG-Lactones Containing Aryl Groups at the sn-1 and sn-2 Positions

Conformationally Constrained Analogues of Diacylglycerol. 21. A Solid-Phase Method of Synthesis of Diacylglycerol Lactones as a Prelude to a Combinatorial Approach for the Synthesis of Protein Kinase C Isozyme-Specific Ligands

Conformationally Constrained Analogues of Diacylglycerol (DAG). 23 † . Hydrophobic Ligand−Protein Interactions versus Ligand−Lipid Interactions of DAG-Lactones with Protein Kinase C (PK-C)

Conformationally Constrained Analogues of Diacylglycerol. 20. The Search for an Elusive Binding Site on Protein Kinase C through Relocation of the Carbonyl Pharmacophore Along the sn-1 Side Chain of 1,2-Diacylglycerol Lactones

An Optimized Protein Kinase C Activating Diacylglycerol Combining High Binding Affinity (K i) with Reduced Lipophilicity (log P)

Inside Cover: Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities (ChemBioChem 14/2010)

North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity (ChemMedChem 8/2009)

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