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Trehalose differentially inhibits aggregation and neurotoxicity of beta-amyloid 40 and 42

Neurobiology of disease, 2005-10, Vol.20 (1), p.74-81

2005

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Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

Scientific reports, 2016-01, Vol.6 (1), p.19393, Article 19393

2016

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Observations of an Extreme Atmospheric River Storm With a Diverse Sensor Network

Earth and space science (Hoboken, N.J.), 2020-08, Vol.7 (8), p.n/a

2020

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Targeted Hydrolysis of Beta-Amyloid with Engineered Antibody Fragments

Current Alzheimer research, 2010-05, Vol.7 (3), p.214-222

2010

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Residues 17-20 and 30-35 of beta-amyloid play critical roles in aggregation

Journal of neuroscience research, 2004-01, Vol.75 (2), p.162-171

2004

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Quantification of Cytokines Involved in Wound Healing Using Surface Plasmon Resonance

Analytical chemistry (Washington), 2005-11, Vol.77 (21), p.7016-7023

2005

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Isolation of an scFv targeting BRG1 using phage display with characterization by AFM

Biochemical and biophysical research communications, 2006-04, Vol.342 (4), p.1123-1129

2006

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Comparison of the domain-level organization of starch hydrolases and related enzymes

Biochemical journal, 1991-11, Vol.280 (1), p.51-55

1991

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Isolation of a Human Single Chain Antibody Fragment Against Oligomeric α-Synuclein that Inhibits Aggregation and Prevents α-Synuclein-induced Toxicity

Journal of molecular biology, 2007-05, Vol.368 (4), p.1132-1144

2007

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P3.085 Novel bio-panning technique to isolate scFv against low concentrations of toxic natural brain derived Abeta oligomers

Parkinsonism & related disorders, 2009, Vol.15, p.S170-S170

2009

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Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer’s β-amyloid

FEBS letters, 2005-08, Vol.579 (21), p.4775-4780

2005

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Anti-oligomeric Aβ Single-chain Variable Domain Antibody Blocks Aβ-induced Toxicity Against Human Neuroblastoma Cells

Journal of molecular biology, 2008-12, Vol.384 (4), p.917-928

2008

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Sequence homology between putative raw-starch binding domains from different starch-degrading enzymes

Biochemical journal, 1989-11, Vol.264 (1), p.309-311

1989

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Solvent and viscosity effects on the rate-limiting product release step of glucoamylase during maltose hydrolysis

Biotechnology progress, 1997-09, Vol.13 (5), p.601-608

1997

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Identification and Repair of Positive Binding Antibodies Containing Randomly Generated Amber Codons from Synthetic Phage Display Libraries

Biotechnology progress, 2006-05, Vol.22 (3), p.919-922

2006

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Evaluation of Isofagomine and Its Derivatives As Potent Glycosidase Inhibitors

Biochemistry (Easton), 1996-02, Vol.35 (8), p.2788-2795

1996

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Pleomorphism of the marine bacterium Teredinobacter turnirae

Letters in applied microbiology, 2001-07, Vol.33 (1), p.56-60

2001

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Catalytic Mechanism of Glucoamylase Probed by Mutagenesis in Conjunction with Hydrolysis of α-d-Glucopyranosyl Fluoride and Maltooligosaccharides

Biochemistry (Easton), 1996-02, Vol.35 (6), p.1865-1871

1996

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Reaction mechanisms of Trp120→Phe and wild-type glucoamylases from Aspergillus niger. Interactions with maltooligodextrins and acarbose

Biochemistry (Easton), 1993-09, Vol.32 (37), p.9686-9693

1993

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Functional roles of the invariant aspartic acid 55, tyrosine 306, and aspartic acid 309 in glucoamylase from Aspergillus awamori studied by mutagenesis

Biochemistry (Easton), 1993-02, Vol.32 (4), p.1113-1117

1993

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Roles of the aromatic side chains in the binding of substrates, inhibitors, and cyclomalto-oligosaccharides to the glucoamylase from Aspergillus niger probed by perturbation difference spectroscopy, chemical modification, and mutagenesis

Carbohydrate research, 1992-04, Vol.227, p.29-44

1992

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Energetic and Mechanistic Studies of Glucoamylase Using Molecular Recognition of Maltose OH Groups Coupled with Site-Directed Mutagenesis

Biochemistry (Easton), 2000-07, Vol.39 (29), p.8585-8592

2000

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Single Chain Fv Antibodies against the 25-35 A beta Fragment Inhibit Aggregation and Toxicity of A beta 42

Biochemistry (Easton), 2006-09, Vol.45 (38), p.11532-11539

2006

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Site-Directed Mutagenesis of the Catalytic Base Glutamic Acid 400 in Glucoamylase from Aspergillus niger and of Tyrosine 48 and Glutamine 401, Both Hydrogen-Bonded to the .gamma.-Carboxylate Group of Glutamic Acid 400

Biochemistry (Easton), 1994-11, Vol.33 (46), p.13808-13816

1994

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Catalytic mechanism of fungal glucoamylase as defined by mutagenesis of Asp176, Glu179 and Glu180 in the enzyme from Aspergillus awamori

Protein engineering, 1990-01, Vol.3 (3), p.193-198

1990

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Trehalose differentially inhibits aggregation and neurotoxicity of beta-amyloid 40 and 42

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

Observations of an Extreme Atmospheric River Storm With a Diverse Sensor Network

Targeted Hydrolysis of Beta-Amyloid with Engineered Antibody Fragments

Residues 17-20 and 30-35 of beta-amyloid play critical roles in aggregation

Quantification of Cytokines Involved in Wound Healing Using Surface Plasmon Resonance

Isolation of an scFv targeting BRG1 using phage display with characterization by AFM

Comparison of the domain-level organization of starch hydrolases and related enzymes

Isolation of a Human Single Chain Antibody Fragment Against Oligomeric α-Synuclein that Inhibits Aggregation and Prevents α-Synuclein-induced Toxicity

P3.085 Novel bio-panning technique to isolate scFv against low concentrations of toxic natural brain derived Abeta oligomers

Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer’s β-amyloid

Anti-oligomeric Aβ Single-chain Variable Domain Antibody Blocks Aβ-induced Toxicity Against Human Neuroblastoma Cells

Sequence homology between putative raw-starch binding domains from different starch-degrading enzymes

Solvent and viscosity effects on the rate-limiting product release step of glucoamylase during maltose hydrolysis

Identification and Repair of Positive Binding Antibodies Containing Randomly Generated Amber Codons from Synthetic Phage Display Libraries

Evaluation of Isofagomine and Its Derivatives As Potent Glycosidase Inhibitors

Pleomorphism of the marine bacterium Teredinobacter turnirae

Catalytic Mechanism of Glucoamylase Probed by Mutagenesis in Conjunction with Hydrolysis of α-d-Glucopyranosyl Fluoride and Maltooligosaccharides

Reaction mechanisms of Trp120→Phe and wild-type glucoamylases from Aspergillus niger. Interactions with maltooligodextrins and acarbose

Functional roles of the invariant aspartic acid 55, tyrosine 306, and aspartic acid 309 in glucoamylase from Aspergillus awamori studied by mutagenesis

Roles of the aromatic side chains in the binding of substrates, inhibitors, and cyclomalto-oligosaccharides to the glucoamylase from Aspergillus niger probed by perturbation difference spectroscopy, chemical modification, and mutagenesis

Energetic and Mechanistic Studies of Glucoamylase Using Molecular Recognition of Maltose OH Groups Coupled with Site-Directed Mutagenesis

Single Chain Fv Antibodies against the 25-35 A beta Fragment Inhibit Aggregation and Toxicity of A beta 42

Site-Directed Mutagenesis of the Catalytic Base Glutamic Acid 400 in Glucoamylase from Aspergillus niger and of Tyrosine 48 and Glutamine 401, Both Hydrogen-Bonded to the .gamma.-Carboxylate Group of Glutamic Acid 400

Catalytic mechanism of fungal glucoamylase as defined by mutagenesis of Asp176, Glu179 and Glu180 in the enzyme from Aspergillus awamori

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