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Epidermal growth factor receptor mutations in lung adenocarcinoma

Laboratory investigation, 2014-02, Vol.94 (2), p.129-137

2014

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Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL

Nature communications, 2017-10, Vol.8 (1), p.1067-14, Article 1067

2017

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Temozolomide and Other Alkylating Agents in Glioblastoma Therapy

Biomedicines, 2019-09, Vol.7 (3), p.69

2019

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Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells

Cancer research (Chicago, Ill.), 2010-11, Vol.70 (22), p.8988-8993

2010

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Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Nature communications, 2023-03, Vol.14 (1), p.1187-1187, Article 1187

2023

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Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma

Nature communications, 2021-09, Vol.12 (1), p.5203-5203, Article 5203

2021

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Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic Responses

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13), p.3513-3526

2017

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Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells

The Journal of clinical investigation, 2011-04, Vol.121 (4), p.1349-1360

2011

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A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy

PloS one, 2015-06, Vol.10 (6), p.e0131670-e0131670

2015

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PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma

PloS one, 2014-12, Vol.9 (12), p.e114583

2014

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Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivo

Oncotarget, 2016-06, Vol.7 (23), p.33512-33528

2016

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Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification

Neurochemical research, 2017-12, Vol.42 (12), p.3382-3389

2017

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Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl‐xL inhibition

EMBO molecular medicine, 2019-10, Vol.11 (10), p.e10769-n/a

2019

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BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma

Oncotarget, 2017-05, Vol.8 (18), p.29558-29573

2017

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Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents

Cancers, 2021-05, Vol.13 (10), p.2504

2021

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DPEP Inhibits Cancer Cell Glucose Uptake, Glycolysis and Survival by Upregulating Tumor Suppressor TXNIP

Cells (Basel, Switzerland), 2024-06, Vol.13 (12), p.1025

2024

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Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells

Neuro-oncology (Charlottesville, Va.), 2009-04, Vol.11 (2), p.122-131

2009

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In Vitro and Clinical Compassionate Use Experiences with the Drug-Repurposing Approach CUSP9v3 in Glioblastoma

Pharmaceuticals (Basel, Switzerland), 2021-11, Vol.14 (12), p.1241

2021

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Dual Inhibition of Bcl-2/Bcl-xL and XPO1 is synthetically lethal in glioblastoma model systems

Scientific reports, 2018-10, Vol.8 (1), p.15383-11, Article 15383

2018

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Targeting Transcription Factors ATF5, CEBPB and CEBPD with Cell-Penetrating Peptides to Treat Brain and Other Cancers

Cells (Basel, Switzerland), 2023-02, Vol.12 (4), p.581

2023

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Epigenetic Targeting of Mcl-1 Is Synthetically Lethal with Bcl-xL/Bcl-2 Inhibition in Model Systems of Glioblastoma

Cancers, 2020-08, Vol.12 (8), p.2137

2020

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Preclinical Characterization of Mitochondria-Targeted Small Molecule Hsp90 Inhibitors, Gamitrinibs, in Advanced Prostate Cancer

Clinical cancer research, 2010-10, Vol.16 (19), p.4779-4788

2010

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Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo

Oncotarget, 2016-03, Vol.7 (11), p.12791-12805

2016

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Therapeutic Drug-Induced Metabolic Reprogramming in Glioblastoma

Cells (Basel, Switzerland), 2022-09, Vol.11 (19), p.2956

2022

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The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin

Molecular cancer therapeutics, 2008-11, Vol.7 (11), p.3566-3574

2008

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Epidermal growth factor receptor mutations in lung adenocarcinoma

Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL

Temozolomide and Other Alkylating Agents in Glioblastoma Therapy

Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells

Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma

Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic Responses

Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells

A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy

PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma

Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivo

Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification

Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl‐xL inhibition

BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma

Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents

DPEP Inhibits Cancer Cell Glucose Uptake, Glycolysis and Survival by Upregulating Tumor Suppressor TXNIP

Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells

In Vitro and Clinical Compassionate Use Experiences with the Drug-Repurposing Approach CUSP9v3 in Glioblastoma

Dual Inhibition of Bcl-2/Bcl-xL and XPO1 is synthetically lethal in glioblastoma model systems

Targeting Transcription Factors ATF5, CEBPB and CEBPD with Cell-Penetrating Peptides to Treat Brain and Other Cancers

Epigenetic Targeting of Mcl-1 Is Synthetically Lethal with Bcl-xL/Bcl-2 Inhibition in Model Systems of Glioblastoma

Preclinical Characterization of Mitochondria-Targeted Small Molecule Hsp90 Inhibitors, Gamitrinibs, in Advanced Prostate Cancer

Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo

Therapeutic Drug-Induced Metabolic Reprogramming in Glioblastoma

The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin

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