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Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations

Oncogene, 2018-06, Vol.37 (24), p.3183-3199

2018

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AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

Cell metabolism, 2013-01, Vol.17 (1), p.113-124

2013

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Metabolic Plasticity as a Determinant of Tumor Growth and Metastasis

Cancer research (Chicago, Ill.), 2016-09, Vol.76 (18), p.5201-5208

2016

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AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3

Autophagy, 2021-12, Vol.17 (12), p.3957-3975

2021

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PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer

Cell metabolism, 2015-10, Vol.22 (4), p.577-589

2015

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Single-cell spatial landscapes of the lung tumour immune microenvironment

Nature (London), 2023-02, Vol.614 (7948), p.548-554

2023

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Optimizing live-cell fluorescence imaging conditions to minimize phototoxicity

Journal of cell science, 2020-02, Vol.133 (4)

2020

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Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

Cell reports (Cambridge), 2019-06, Vol.27 (13), p.3902-3915.e6

2019

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Metabolic Profiles Associated With Metformin Efficacy in Cancer

Frontiers in endocrinology (Lausanne), 2018-08, Vol.9, p.372-372

2018

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Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

Nature genetics, 2014-05, Vol.46 (5), p.462-466

2014

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Antibody-mediated targeting of Claudins in cancer

Frontiers in oncology, 2024, Vol.14, p.1320766-1320766

2024

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CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro

Scientific reports, 2019-11, Vol.9 (1), p.16317-17, Article 16317

2019

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LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis

Nature communications, 2017-04, Vol.8 (1), p.15059-15059, Article 15059

2017

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Dual MAPK Inhibition Is an Effective Therapeutic Strategy for a Subset of Class II BRAF Mutant Melanomas

Clinical cancer research, 2018-12, Vol.24 (24), p.6483-6494

2018

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Neutrophils: Orchestrators of the Malignant Phenotype

Frontiers in immunology, 2020-08, Vol.11, p.1778-1778

2020

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ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties

PloS one, 2010-08, Vol.5 (8), p.e12093-e12093

2010

Volltextzugriff (PDF)

Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis

Translational oncology, 2019-03, Vol.12 (3), p.462-474

2019

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PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target

The Journal of clinical investigation, 2011-12, Vol.121 (12), p.4655-4669

2011

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Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

eLife, 2021-06, Vol.10

2021

Volltextzugriff (PDF)

p66ShcA functions as a contextual promoter of breast cancer metastasis

Breast cancer research : BCR, 2020-01, Vol.22 (1), p.7-7, Article 7

2020

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Claudin-2 Promotes Breast Cancer Liver Metastasis by Facilitating Tumor Cell Interactions with Hepatocytes

Molecular and Cellular Biology, 2012-08, Vol.32 (15), p.2979-2991

2012

Volltextzugriff (PDF)

The Underlying Biology and Therapeutic Vulnerabilities of Leptomeningeal Metastases in Adult Solid Cancers

Cancers, 2021-02, Vol.13 (4), p.732

2021

Volltextzugriff (PDF)

CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti‐VEGF treatment or docetaxel in a transgenic mouse model

International journal of cancer, 2011-07, Vol.129 (1), p.225-232

2011

Volltextzugriff (PDF)

MAPK Pathway Inhibitors Sensitize BRAF-Mutant Melanoma to an Antibody-Drug Conjugate Targeting GPNMB

Clinical cancer research, 2016-12, Vol.22 (24), p.6088-6098

2016

Volltextzugriff (PDF)

Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

Breast cancer research : BCR, 2018-01, Vol.20 (1), p.9-9, Article 9

2018

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Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

Metabolic Plasticity as a Determinant of Tumor Growth and Metastasis

AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3

PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer

Single-cell spatial landscapes of the lung tumour immune microenvironment

Optimizing live-cell fluorescence imaging conditions to minimize phototoxicity

Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

Metabolic Profiles Associated With Metformin Efficacy in Cancer

Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

Antibody-mediated targeting of Claudins in cancer

CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro

LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis

Dual MAPK Inhibition Is an Effective Therapeutic Strategy for a Subset of Class II BRAF Mutant Melanomas

Neutrophils: Orchestrators of the Malignant Phenotype

ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties

Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis

PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

p66ShcA functions as a contextual promoter of breast cancer metastasis

Claudin-2 Promotes Breast Cancer Liver Metastasis by Facilitating Tumor Cell Interactions with Hepatocytes

The Underlying Biology and Therapeutic Vulnerabilities of Leptomeningeal Metastases in Adult Solid Cancers

CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti‐VEGF treatment or docetaxel in a transgenic mouse model

MAPK Pathway Inhibitors Sensitize BRAF-Mutant Melanoma to an Antibody-Drug Conjugate Targeting GPNMB

Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

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