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Phase Ia/b, Open-Label, Multicenter Study of AZD4635 (an Adenosine A2A Receptor Antagonist) as Monotherapy or Combined with Durvalumab, in Patients with Solid Tumors

Clinical cancer research, 2022-11, Vol.28 (22), p.4871-4884

2022

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Immune Cell Abundance and T-cell Receptor Landscapes Suggest New Patient Stratification Strategies in Head and Neck Squamous Cell Carcinoma

Cancer research communications, 2023-10, Vol.3 (10), p.2133-2145

2023

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Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences

Nature genetics, 2024-09, Vol.56 (9), p.1832-1840

2024

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Elevating life science R&D success with AI: a framework

Drug discovery today, 2024-12, Vol.29 (12), p.104211, Article 104211

Sidders, Ben

2024

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Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer

Nature communications, 2022-03, Vol.13 (1), p.1667-14, Article 1667

2022

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Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response

Clinical cancer research, 2020-05, Vol.26 (9), p.2176-2187

2020

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HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

Pain (Amsterdam), 2013-09, Vol.154 (9), p.1668-1679

2013

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Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens

Molecular systems biology, 2020-07, Vol.16 (7), p.e9405-n/a

2020

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Network-Based Drug Discovery: Coupling Network Pharmacology with Phenotypic Screening for Neuronal Excitability

Journal of molecular biology, 2018-09, Vol.430 (18), p.3005-3015

2018

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Causal reasoning on biological networks: interpreting transcriptional changes

Bioinformatics (Oxford, England), 2012-04, Vol.28 (8), p.1114-1121

2012

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Pan-Cancer Proteomics Analysis to Identify Tumor-Enriched and Highly Expressed Cell Surface Antigens as Potential Targets for Cancer Therapeutics

Molecular & cellular proteomics, 2023-09, Vol.22 (9), p.100626-100626, Article 100626

2023

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Hypervirulent Mutant of Mycobacterium tuberculosis Resulting from Disruption of the mce1 Operon

Proceedings of the National Academy of Sciences - PNAS, 2003-12, Vol.100 (26), p.15918-15923

2003

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Abstract 902: Explainable AI: Graph machine learning for response prediction and biomarker discovery

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.902-902

2024

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Abstract 3379: Cancer dependency signatures for line of sight genomic alterations in squamous cell lung cancer yield rational targets

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3379-3379

2020

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PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8 + T-cell activity

Journal for immunotherapy of cancer, 2018-12, Vol.6 (1), p.158-158, Article 158

2018

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Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks

BMC bioinformatics, 2016-08, Vol.17 (1), p.318-318, Article 318

2016

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Abstract 493: The landscape of adenosine signaling in cancer

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.493-493

2019

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Abstract 390: Identification of a novel immunosuppressive myeloid gene expression signature for clinical biomarker development

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.390-390

2021

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Screening of Highly Expressed Mycobacterial Genes Identifies Rv3615c as a Useful Differential Diagnostic Antigen for the Mycobacterium tuberculosis Complex

Infection and Immunity, 2008-09, Vol.76 (9), p.3932-3939

2008

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Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice

Journal of medical microbiology, 2008-02, Vol.57 (2), p.164-170

2008

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Author Correction: Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

NPJ systems biology and applications, 2024-08, Vol.10 (1), p.83-1, Article 83

2024

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Abstract 4888: Multi-modal knowledge graphs enhance patient stratification & biomarker discovery

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.4888-4888

2024

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A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells

PloS one, 2015-06, Vol.10 (6), p.e0130379-e0130379

2015

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Selection, Optimization, and Pharmacokinetic Properties of a Novel, Potent Antiviral Locked Nucleic Acid-Based Antisense Oligomer Targeting Hepatitis C Virus Internal Ribosome Entry Site

Antimicrobial Agents and Chemotherapy, 2011-07, Vol.55 (7), p.3105-3114

2011

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Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

NPJ systems biology and applications, 2024-06, Vol.10 (1), p.68-15, Article 68

2024

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Phase Ia/b, Open-Label, Multicenter Study of AZD4635 (an Adenosine A2A Receptor Antagonist) as Monotherapy or Combined with Durvalumab, in Patients with Solid Tumors

Immune Cell Abundance and T-cell Receptor Landscapes Suggest New Patient Stratification Strategies in Head and Neck Squamous Cell Carcinoma

Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences

Elevating life science R&D success with AI: a framework

Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer

Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response

HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens

Network-Based Drug Discovery: Coupling Network Pharmacology with Phenotypic Screening for Neuronal Excitability

Causal reasoning on biological networks: interpreting transcriptional changes

Pan-Cancer Proteomics Analysis to Identify Tumor-Enriched and Highly Expressed Cell Surface Antigens as Potential Targets for Cancer Therapeutics

Hypervirulent Mutant of Mycobacterium tuberculosis Resulting from Disruption of the mce1 Operon

Abstract 902: Explainable AI: Graph machine learning for response prediction and biomarker discovery

Abstract 3379: Cancer dependency signatures for line of sight genomic alterations in squamous cell lung cancer yield rational targets

PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8 + T-cell activity

Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks

Abstract 493: The landscape of adenosine signaling in cancer

Abstract 390: Identification of a novel immunosuppressive myeloid gene expression signature for clinical biomarker development

Screening of Highly Expressed Mycobacterial Genes Identifies Rv3615c as a Useful Differential Diagnostic Antigen for the Mycobacterium tuberculosis Complex

Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice

Author Correction: Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

Abstract 4888: Multi-modal knowledge graphs enhance patient stratification & biomarker discovery

A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells

Selection, Optimization, and Pharmacokinetic Properties of a Novel, Potent Antiviral Locked Nucleic Acid-Based Antisense Oligomer Targeting Hepatitis C Virus Internal Ribosome Entry Site

Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

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