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Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability

Molecular psychiatry, 2021-11, Vol.26 (11), p.6704-6722

2021

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High-potency ligands for DREADD imaging and activation in rodents and monkeys

Nature communications, 2019-10, Vol.10 (1), p.4627-12, Article 4627

2019

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New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion

Molecular psychiatry, 2020-09, Vol.25 (9), p.2070-2085

2020

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Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search

Molecular psychiatry, 2022-10, Vol.27 (10), p.4144-4156

2022

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Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors

Translational psychiatry, 2021-02, Vol.11 (1), p.59-59, Article 59

2021

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Mechanism and Time Course of Cocaine-Induced Long-Term Potentiation in the Ventral Tegmental Area

The Journal of neuroscience, 2008-09, Vol.28 (37), p.9092-9100

2008

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The Enduring Impact of Pharmacological Reviews -Editorial

Pharmacological reviews, 2024-09, Vol.76 (5), p.620-621

Sibley, David R

2024

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A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity

Science signaling, 2020-02, Vol.13 (617)

2020

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Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D1 Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation

International journal of molecular sciences, 2023-04, Vol.24 (7), p.6599

2023

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A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors

Cell reports (Cambridge), 2019-10, Vol.29 (5), p.1147-1163.e5

2019

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Structural basis for Na(+)-sensitivity in dopamine D2 and D3 receptors

Chemical communications (Cambridge, England), 2015-05, Vol.51 (41), p.8618-8621

2015

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Protein Kinase C Mediates Phosphorylation, Desensitization, and Trafficking of the D2 Dopamine Receptor

The Journal of biological chemistry, 2004-11, Vol.279 (47), p.49533-49541

2004

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G Protein-coupled Receptor Kinase-mediated Phosphorylation Regulates Post-endocytic Trafficking of the D2 Dopamine Receptor

The Journal of biological chemistry, 2009-05, Vol.284 (22), p.15038-15051

2009

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Imaging the high-affinity state of the dopamine D₂ receptor in vivo: Fact or fiction?

Biochemical pharmacology, 2012-01, Vol.83 (2), p.193-198

2012

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Dopaminergic signaling in the cochlea: receptor expression patterns and deletion phenotypes

The Journal of neuroscience, 2012-01, Vol.32 (1), p.344-355

2012

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Dopamine D5 receptor-mediated decreases in mitochondrial reactive oxygen species production are cAMP and autophagy dependent

Hypertension research, 2021-06, Vol.44 (6), p.628-641

2021

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G Protein-coupled Receptor Kinase-2 Constitutively Regulates D2 Dopamine Receptor Expression and Signaling Independently of Receptor Phosphorylation

The Journal of biological chemistry, 2009-12, Vol.284 (49), p.34103-34115

2009

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N-(3-Fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as Selective Dopamine D3 Receptor Ligands: Critical Role of the Carboxamide Linker for D3 Receptor Selectivity

Journal of medicinal chemistry, 2011-05, Vol.54 (10), p.3581-3594

2011

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Novel Cryo-EM structures of the D1 dopamine receptor unlock its therapeutic potential

Signal transduction and targeted therapy, 2021-05, Vol.6 (1), p.205-205, Article 205

2021

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D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

NeuroImage (Orlando, Fla.), 2010-05, Vol.50 (4), p.1402-1407

2010

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The Dopamine D5 Receptor Is Involved in Working Memory

Frontiers in pharmacology, 2017-10, Vol.8, p.666-666

2017

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G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation

Biomolecules (Basel, Switzerland), 2023-10, Vol.13 (10), p.1552

2023

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The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors

PLoS computational biology, 2018-01, Vol.14 (1), p.e1005948-e1005948

2018

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Comparison of dopamine D1 and D5 receptor knockout mice for cocaine locomotor sensitization

Psychopharmacologia, 2008-09, Vol.200 (1), p.117-127

2008

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Advances and challenges in the search for D 2 and D 3 dopamine receptor-selective compounds

Cellular signalling, 2018-01, Vol.41, p.75

2018

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Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability

High-potency ligands for DREADD imaging and activation in rodents and monkeys

New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion

Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search

Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors

Mechanism and Time Course of Cocaine-Induced Long-Term Potentiation in the Ventral Tegmental Area

The Enduring Impact of Pharmacological Reviews -Editorial

A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity

Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D1 Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation

A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors

Structural basis for Na(+)-sensitivity in dopamine D2 and D3 receptors

Protein Kinase C Mediates Phosphorylation, Desensitization, and Trafficking of the D2 Dopamine Receptor

G Protein-coupled Receptor Kinase-mediated Phosphorylation Regulates Post-endocytic Trafficking of the D2 Dopamine Receptor

Imaging the high-affinity state of the dopamine D₂ receptor in vivo: Fact or fiction?

Dopaminergic signaling in the cochlea: receptor expression patterns and deletion phenotypes

Dopamine D5 receptor-mediated decreases in mitochondrial reactive oxygen species production are cAMP and autophagy dependent

G Protein-coupled Receptor Kinase-2 Constitutively Regulates D2 Dopamine Receptor Expression and Signaling Independently of Receptor Phosphorylation

N-(3-Fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as Selective Dopamine D3 Receptor Ligands: Critical Role of the Carboxamide Linker for D3 Receptor Selectivity

Novel Cryo-EM structures of the D1 dopamine receptor unlock its therapeutic potential

D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

The Dopamine D5 Receptor Is Involved in Working Memory

G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation

The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors

Comparison of dopamine D1 and D5 receptor knockout mice for cocaine locomotor sensitization

Advances and challenges in the search for D 2 and D 3 dopamine receptor-selective compounds

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