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Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy

The Journal of cell biology, 2020-09, Vol.219 (9), p.1

2020

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Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation

Nature communications, 2014-09, Vol.5 (1), p.4806-4806, Article 4806

2014

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Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.4865-4869

2016

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A Thiol-Reactive Fluorescence Probe Based on Donor-Excited Photoinduced Electron Transfer: Key Role of Ortho Substitution

Organic letters, 2007-08, Vol.9 (17), p.3375-3377

2007

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In Silico Prediction of N-Nitrosamine Formation Pathways of Pharmaceutical Products

Chemical and Pharmaceutical Bulletin, 2024/02/01, Vol.72(2), pp.166-172

2024

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Approach to Establishment of Control Strategy for Oral Solid Dosage Forms Using Continuous Manufacturing

Chemical and Pharmaceutical Bulletin, 2021/02/01, Vol.69(2), pp.211-217

2021

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Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules

Molecular pharmacology, 2017-03, Vol.91 (3), p.159-166

2017

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Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1793-1796

2012

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Development of an ON/OFF switchable fluorescent probe targeting His tag fused proteins in living cells

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (15), p.3417-3422

2017

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Design and synthesis of cell-permeable fluorescent nitrilotriacetic acid derivatives

Bioorganic & medicinal chemistry, 2018-11, Vol.26 (20), p.5494-5498

2018

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Synthesis and evaluation of raloxifene derivatives as a selective estrogen receptor down-regulator

Bioorganic & medicinal chemistry, 2016-07, Vol.24 (13), p.2914-2919

2016

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Targeted Protein Degradation by Chimeric Compounds using Hydrophobic E3 Ligands and Adamantane Moiety

Pharmaceuticals (Basel, Switzerland), 2020-02, Vol.13 (3), p.34

2020

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Tamoxifen and Fulvestrant Hybrids Showed Potency as Selective Estrogen Receptor Down-Regulators

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2017-01, Vol.13 (3), p.206

2017

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Design and synthesis of novel selective estrogen receptor degradation inducers based on the diphenylheptane skeleton

MedChemComm, 2017-01, Vol.8 (1), p.239-246

2017

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4-Hydroxy-3-methoxymethamphetamine Glucuronide as a Phase II Metabolite of 3,4-Methylenedioxymethamphetamine: Enzyme-Assisted Synthesis and Involvement of Human Hepatic Uridine 5′-Diphosphate-Glucuronosyltransferase 2B15 in the Glucuronidation

Chemical and Pharmaceutical Bulletin, 2009/05/01, Vol.57(5), pp.472-475

2009

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Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins

ACS chemical biology, 2019-12, Vol.14 (12), p.2822-2832

2019

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TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains

Molecular cell, 2021-04, Vol.81 (7), p.1411-1424.e7

2021

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Enzyme-assisted synthesis of the glucuronide conjugate of psilocin, an hallucinogenic component of magic mushrooms

Drug testing and analysis, 2011-09, Vol.3 (9), p.594-596

2011

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Discovery of non-proteinogenic amino acids inhibiting biofilm formation by S. aureus and methicillin-resistant S. aureus

Bioorganic & medicinal chemistry letters, 2021-09, Vol.48, p.128259-128259, Article 128259

2021

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Amphipathic short helix-stabilized peptides with cell-membrane penetrating ability

Bioorganic & medicinal chemistry, 2014-04, Vol.22 (8), p.2403-2408

2014

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Development of a Small Hybrid Molecule That Mediates Degradation of His-Tag Fused Proteins

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.576-582

2018

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Synthesis of a bis-cationic α,α-disubstituted amino acid (9-amino-bispidine-9-carboxylic acid) and its effects on the conformational properties of peptides

Tetrahedron, 2015-04, Vol.71 (15), p.2241-2245

2015

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Abstract C125: Development of small molecule chimeras that recruit aryl-hydrocarbon receptor (AhR) E3 ligase to induce degradation of target proteins

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.C125-C125

2019

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An Activity-Based Probe for Studying Crosslinking in Live Bacteria

Angewandte Chemie, 2015-09, Vol.127 (36), p.10638-10642

2015

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Comprehensive Synthesis of 20 Fentanyl Derivatives for Their Rapid Differentiation by GC-MS Analysis

Heterocycles, 2023, Vol.106 (1), p.82

2023

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Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy

Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation

Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

A Thiol-Reactive Fluorescence Probe Based on Donor-Excited Photoinduced Electron Transfer: Key Role of Ortho Substitution

In Silico Prediction of N-Nitrosamine Formation Pathways of Pharmaceutical Products

Approach to Establishment of Control Strategy for Oral Solid Dosage Forms Using Continuous Manufacturing

Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules

Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Development of an ON/OFF switchable fluorescent probe targeting His tag fused proteins in living cells

Design and synthesis of cell-permeable fluorescent nitrilotriacetic acid derivatives

Synthesis and evaluation of raloxifene derivatives as a selective estrogen receptor down-regulator

Targeted Protein Degradation by Chimeric Compounds using Hydrophobic E3 Ligands and Adamantane Moiety

Tamoxifen and Fulvestrant Hybrids Showed Potency as Selective Estrogen Receptor Down-Regulators

Design and synthesis of novel selective estrogen receptor degradation inducers based on the diphenylheptane skeleton

4-Hydroxy-3-methoxymethamphetamine Glucuronide as a Phase II Metabolite of 3,4-Methylenedioxymethamphetamine: Enzyme-Assisted Synthesis and Involvement of Human Hepatic Uridine 5′-Diphosphate-Glucuronosyltransferase 2B15 in the Glucuronidation

Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins

TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains

Enzyme-assisted synthesis of the glucuronide conjugate of psilocin, an hallucinogenic component of magic mushrooms

Discovery of non-proteinogenic amino acids inhibiting biofilm formation by S. aureus and methicillin-resistant S. aureus

Amphipathic short helix-stabilized peptides with cell-membrane penetrating ability

Development of a Small Hybrid Molecule That Mediates Degradation of His-Tag Fused Proteins

Synthesis of a bis-cationic α,α-disubstituted amino acid (9-amino-bispidine-9-carboxylic acid) and its effects on the conformational properties of peptides

Abstract C125: Development of small molecule chimeras that recruit aryl-hydrocarbon receptor (AhR) E3 ligase to induce degradation of target proteins

An Activity-Based Probe for Studying Crosslinking in Live Bacteria

Comprehensive Synthesis of 20 Fentanyl Derivatives for Their Rapid Differentiation by GC-MS Analysis

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