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Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs

Alzheimer's & dementia, 2018-02, Vol.14 (2), p.230-242

2018

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Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases

International journal of molecular sciences, 2022-12, Vol.23 (24), p.15457

2022

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Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles

Hypertension (Dallas, Tex. 1979), 2016-05, Vol.67 (5), p.1006-1013

2016

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A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories

Scientific reports, 2019-05, Vol.9 (1), p.7368, Article 7368

2019

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Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs

Scientific reports, 2020-10, Vol.10 (1), p.18326-18326, Article 18326

2020

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Photothermal Confocal Spectromicroscopy of Multiple Cellular Chromophores and Fluorophores

Biophysical journal, 2012-02, Vol.102 (3), p.672-681

2012

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Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation

Frontiers in aging neuroscience, 2022-08, Vol.14, p.938117-938117

2022

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Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer’s Disease

Pharmaceutics, 2022-06, Vol.14 (7), p.1354

2022

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Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation

Molecules (Basel, Switzerland), 2020-08, Vol.25 (16), p.3610

2020

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Cross-talk between LOX-1 and PCSK9 in vascular tissues

Cardiovascular research, 2015-09, Vol.107 (4), p.556-567

2015

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Dysfunctional homologous recombination mediates genomic instability and progression in myeloma

Blood, 2009-03, Vol.113 (10), p.2290-2297

2009

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Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation

Antioxidants & redox signaling, 2017-12, Vol.27 (17), p.1383

2017

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Advances in understanding the molecular basis of clonal hematopoiesis

Trends in molecular medicine, 2022-05, Vol.28 (5), p.360-377

2022

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A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease

Frontiers in molecular neuroscience, 2019-12, Vol.12, p.310-310

2019

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“Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation

Aging cell, 2021-05, Vol.20 (5), p.e13326-n/a

2021

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Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration

Metabolic brain disease, 2022-01, Vol.37 (1), p.147-152

2022

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Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain

Molecular and cellular biochemistry, 2023-11

2023

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In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration

Scientific reports, 2023-02, Vol.13 (1), p.2096-2096, Article 2096

2023

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Model biological systems demonstrate the inducibility of pathways that strongly reduce cryoprotectant toxicity

Cryobiology, 2024-06, Vol.115, p.104881-104881, Article 104881

2024

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Aspirin inhibits oxidant stress, reduces age-associated functional declines, and extends lifespan of Caenorhabditis elegans

Antioxidants & redox signaling, 2013-02, Vol.18 (5), p.481

2013

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Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer’s disease

Bioorganic & medicinal chemistry, 2021-09, Vol.45, p.116311-116311, Article 116311

2021

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Remarkable longevity and stress resistance of nematode PI3K‐null mutants

Aging cell, 2008-02, Vol.7 (1), p.13-22

2008

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Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls

Aging cell, 2016-10, Vol.15 (5), p.924-939

2016

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Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease

Scientific reports, 2021-10, Vol.11 (1), p.19732-19732, Article 19732

2021

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Leave-one-out-analysis (LOOA): web-based tool to predict influential proteins and interactions in aggregate-crosslinking proteomic data

Bioinformation, 2024, Vol.20 (1), p.4-10

2024

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Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs

Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases

Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles

A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories

Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs

Photothermal Confocal Spectromicroscopy of Multiple Cellular Chromophores and Fluorophores

Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation

Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer’s Disease

Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation

Cross-talk between LOX-1 and PCSK9 in vascular tissues

Dysfunctional homologous recombination mediates genomic instability and progression in myeloma

Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation

Advances in understanding the molecular basis of clonal hematopoiesis

A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease

“Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation

Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration

Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain

In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration

Model biological systems demonstrate the inducibility of pathways that strongly reduce cryoprotectant toxicity

Aspirin inhibits oxidant stress, reduces age-associated functional declines, and extends lifespan of Caenorhabditis elegans

Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer’s disease

Remarkable longevity and stress resistance of nematode PI3K‐null mutants

Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls

Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease

Leave-one-out-analysis (LOOA): web-based tool to predict influential proteins and interactions in aggregate-crosslinking proteomic data

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