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PtdIns5P: News and views of its appearance, disappearance and deeds

Archives of biochemistry and biophysics, 2013-10, Vol.538 (2), p.171-180

Shisheva, Assia

2013

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PIKfyve: Partners, significance, debates and paradoxes

Cell biology international, 2008-06, Vol.32 (6), p.591-604

Shisheva, Assia

2008

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Small molecule PIKfyve inhibitors as cancer therapeutics: Translational promises and limitations

Toxicology and applied pharmacology, 2019-11, Vol.383, p.114771, Article 114771

2019

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Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve‐dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012)

BioEssays, 2015-03, Vol.37 (3), p.267-277

2015

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Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation

PloS one, 2018, Vol.13 (9), p.e0204532-e0204532

2018

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Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis

Biochimica et biophysica acta, 2015-05, Vol.1853 (5), p.1240-1250

2015

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YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes

Biochemical and biophysical research communications, 2009-05, Vol.382 (3), p.566-570

2009

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ArPIKfyve Homomeric and Heteromeric Interactions Scaffold PIKfyve and Sac3 in a Complex to Promote PIKfyve Activity and Functionality

Journal of molecular biology, 2008-12, Vol.384 (4), p.766-779

2008

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The PIKfyve–ArPIKfyve–Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines

Biochemical and biophysical research communications, 2013-10, Vol.440 (2), p.342-347

2013

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cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease

Molecular pharmacology, 2014-03, Vol.85 (3), p.441-450

2014

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Mammalian Cell Morphology and Endocytic Membrane Homeostasis Require Enzymatically Active Phosphoinositide 5-Kinase PIKfyve

The Journal of biological chemistry, 2001-07, Vol.276 (28), p.26141-26147

2001

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Acquisition of Unprecedented Phosphatidylinositol 3,5-Bisphosphate Rise in Hyperosmotically Stressed 3T3-L1 Adipocytes, Mediated by ArPIKfyve-PIKfyve Pathway

The Journal of biological chemistry, 2005-03, Vol.280 (9), p.7883-7889

2005

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Myotubularin Regulates the Function of the Late Endosome through the GRAM Domain-Phosphatidylinositol 3,5-Bisphosphate Interaction

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13817-13824

2004

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Host PI(3,5)P2 Activity Is Required for Plasmodium berghei Growth During Liver Stage Infection

Traffic (Copenhagen, Denmark), 2014-10, Vol.15 (10), p.1066-1082

2014

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Role for a Novel Signaling Intermediate, Phosphatidylinositol 5-Phosphate, in Insulin-Regulated F-Actin Stress Fiber Breakdown and GLUT4 Translocation

Endocrinology (Philadelphia), 2004-11, Vol.145 (11), p.4853-4865

2004

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Phosphatases: The New Brakes for Cancer Development?

Enzyme Research, 2012, Vol.2012, p.659649-11

2012

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ArPIKfyve–PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes

Experimental cell research, 2007-07, Vol.313 (11), p.2404-2416

2007

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Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3

American journal of physiology: endocrinology and metabolism, 2008-09, Vol.295 (3), p.E536-E544

Shisheva, Assia

2008

Volltextzugriff (PDF)

Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P 3

American journal of physiology: endocrinology and metabolism, 2008-09, Vol.295 (3), p.E536-E544

Shisheva, Assia

2008

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Regulating Glut4 vesicle dynamics by phosphoinositide kinases and phosphoinositide phosphatases

Frontiers in bioscience, 2003-09, Vol.8, p.s945

Shisheva, Assia

2003

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Phosphatidylinositol 5-Phosphate Biosynthesis Is Linked to PIKfyve and Is Involved in Osmotic Response Pathway in Mammalian Cells

The Journal of biological chemistry, 2002-12, Vol.277 (49), p.47276-47284

2002

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Kinesin Adapter JLP Links PIKfyve to Microtubule-based Endosome-to-Trans-Golgi Network Traffic of Furin

The Journal of biological chemistry, 2009-02, Vol.284 (6), p.3750-3761

2009

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The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (19), p.9229-9237

2007

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An Efficient and Improved Methodology for the Screening of Industrially Valuable Xylano-Pectino-Cellulolytic Microbes

Enzyme Research, 2015, Vol.2015, p.725281-7

2015

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Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636

American Journal of Physiology: Cell Physiology, 2012-08, Vol.303 (4), p.C436-C446

2012

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PtdIns5P: News and views of its appearance, disappearance and deeds

PIKfyve: Partners, significance, debates and paradoxes

Small molecule PIKfyve inhibitors as cancer therapeutics: Translational promises and limitations

Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve‐dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012)

Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation

Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis

YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes

ArPIKfyve Homomeric and Heteromeric Interactions Scaffold PIKfyve and Sac3 in a Complex to Promote PIKfyve Activity and Functionality

The PIKfyve–ArPIKfyve–Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines

cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease

Mammalian Cell Morphology and Endocytic Membrane Homeostasis Require Enzymatically Active Phosphoinositide 5-Kinase PIKfyve

Acquisition of Unprecedented Phosphatidylinositol 3,5-Bisphosphate Rise in Hyperosmotically Stressed 3T3-L1 Adipocytes, Mediated by ArPIKfyve-PIKfyve Pathway

Myotubularin Regulates the Function of the Late Endosome through the GRAM Domain-Phosphatidylinositol 3,5-Bisphosphate Interaction

Host PI(3,5)P2 Activity Is Required for Plasmodium berghei Growth During Liver Stage Infection

Role for a Novel Signaling Intermediate, Phosphatidylinositol 5-Phosphate, in Insulin-Regulated F-Actin Stress Fiber Breakdown and GLUT4 Translocation

Phosphatases: The New Brakes for Cancer Development?

ArPIKfyve–PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes

Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3

Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P 3

Regulating Glut4 vesicle dynamics by phosphoinositide kinases and phosphoinositide phosphatases

Phosphatidylinositol 5-Phosphate Biosynthesis Is Linked to PIKfyve and Is Involved in Osmotic Response Pathway in Mammalian Cells

Kinesin Adapter JLP Links PIKfyve to Microtubule-based Endosome-to-Trans-Golgi Network Traffic of Furin

The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus

An Efficient and Improved Methodology for the Screening of Industrially Valuable Xylano-Pectino-Cellulolytic Microbes

Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636

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