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Preparation of (4-Amino-1-Hydroxybutylidene)bisphosphonic Acid Sodium Salt, MK-217 (Alendronate Sodium). An Improved Procedure for the Preparation of 1-Hydroxy-1,1-bisphosphonic Acids

Journal of organic chemistry, 1995-12, Vol.60 (25), p.8310-8312

1995

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Origins of the enantioselectivity observed in oxazaborolidine-catalyzed reductions of ketones

Journal of organic chemistry, 1993-02, Vol.58 (4), p.799-801

1993

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Comprehensive heterocyclic chemistry II: a review of the literature 1982-1995 : the structure, reactions, synthesis, and uses of heterocyclic compounds

1996

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A modified Bischler-Napieralski procedure for the synthesis of 3-aryl-3,4-dihydroisoquinolines

Journal of organic chemistry, 1991-10, Vol.56 (21), p.6034-6038

1991

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Mechanism of an acid chloride-imine reaction by low-temperature FT-IR: .beta.-lactam formation occurs exclusively through a ketene intermediate

Journal of organic chemistry, 1989-08, Vol.54 (16), p.3792-3796

1989

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Design and development of practical asymmetric syntheses of drug candidates

Pure and applied chemistry, 1997-01, Vol.69 (3), p.453-458

Shinkai, I.

1997

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Measurement and Correlation of Phase Equilibria for Water + Decane + 2-Propanol, Water + Hexane + 2-Propanol, and Water + Decane + 2-Butanol Ternary Systems at 573 and 593 K and 15.0 and 20.0 MPa

Journal of chemical and engineering data, 2004-03, Vol.49 (2), p.301-305

2004

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Chemistry and Biology of the Immunosuppressant (-) -FK-506

Journal of Synthetic Organic Chemistry, Japan, 1992/06/01, Vol.50(6), pp.522-534

1992

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Valacyclovir

Bioorganic & medicinal chemistry, 1996, Vol.4 (1), p.1-2

1996

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Alendronate

Bioorganic & medicinal chemistry, 1996, Vol.4 (1), p.3-4

1996

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New drugs—reports of new drugs recently approved by the FDA lamivudine

Bioorganic & medicinal chemistry, 1997-04, Vol.5 (4), p.639-640

1997

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New ring systems from 1,2-benzisothiazole-1,1-dioxides and related compounds

Tetrahedron, 1996-02, Vol.52 (9), p.3339-3354

1996

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A practical asymmetric synthesis of a novel topically active carbonic anhydrase inhibitor

Journal of heterocyclic chemistry, 1992-05, Vol.29 (3), p.627-630

Shinkai, Ichiro

1992

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Stereocontrolled addition of propionate homoenolate equivalents to chiral α-amino aldehydes

Tetrahedron letters, 1991-04, Vol.32 (16), p.1867-1870

1991

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1-CHLORO-(2S,3S)-DIHYDROXYCYCLOHEXA-4,6-DIENE

Organic syntheses, 1999, Vol.76, p.77

1999

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プロセス化学の展開(オピニオン,<特集>医薬プロセスケミストリーの新世紀)

ファルマシア, 2002/03/01, Vol.38(3), pp.189

新開, 一朗

2002

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Asymmetric bioreduction of cyclohexylphenyl ketone to its corresponding alcohol (+) cyclohexylphenyl alcohol by the yeast Candida magnoliae MY 1785

Journal of fermentation and bioengineering, 1997-01, Vol.83 (4), p.395-396

1997

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Spirodioxolane intermediates in the reaction of 2-(trimethylsilyl)thiazole with aldehydes. Support for the 2-ylide mechanism

Journal of organic chemistry, 1993-05, Vol.58 (11), p.3196-3200

1993

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Synthesis of PAF antagonist MK-287

Journal of organic chemistry, 1992-12, Vol.57 (26), p.7044-7052

1992

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A stereoselective synthesis of a key 1β-methylcarbapenem intermediate via a diastereoselective decarboxylation

Tetrahedron letters, 1994-04, Vol.35 (15), p.2275-2278

1994

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Regional Management and e-Democracy in the Information Society: Communications among Citizens and Officials on the Website Provided by Local Governments for Good Local Management

Digital Economy and Social Design, 2005, p.210-232

2005

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Stereocontrolled addition of chiral, non-racemic amide homoenolates to t-Boc-(S)-phenylalaninal

Tetrahedron letters, 1992-10, Vol.33 (44), p.6599-6602

1992

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Diastereoselective routes to a 1β-methylcarbapenem key intermediate. Scope of ate complex formation between ester enolates and organoboranes and- alanes

Journal of organic chemistry, 1992-04, Vol.57 (8), p.2411-2418

1992

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A facially-selective protonation controls the stereochemistry of a key intermediate in the synthesis of 1β-methylcarbapenems

Journal of organic chemistry, 1994-07, Vol.59 (14), p.3749-3751

1994

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An Unusual Stereoselective Decarboxylation: A Key Reaction to an Important Intermediate for Carbapenem Antibiotics

Journal of organic chemistry, 1995-12, Vol.60 (26), p.8367-8370

1995

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Preparation of (4-Amino-1-Hydroxybutylidene)bisphosphonic Acid Sodium Salt, MK-217 (Alendronate Sodium). An Improved Procedure for the Preparation of 1-Hydroxy-1,1-bisphosphonic Acids

Origins of the enantioselectivity observed in oxazaborolidine-catalyzed reductions of ketones

Comprehensive heterocyclic chemistry II: a review of the literature 1982-1995 : the structure, reactions, synthesis, and uses of heterocyclic compounds

A modified Bischler-Napieralski procedure for the synthesis of 3-aryl-3,4-dihydroisoquinolines

Mechanism of an acid chloride-imine reaction by low-temperature FT-IR: .beta.-lactam formation occurs exclusively through a ketene intermediate

Design and development of practical asymmetric syntheses of drug candidates

Measurement and Correlation of Phase Equilibria for Water + Decane + 2-Propanol, Water + Hexane + 2-Propanol, and Water + Decane + 2-Butanol Ternary Systems at 573 and 593 K and 15.0 and 20.0 MPa

Chemistry and Biology of the Immunosuppressant (-) -FK-506

Valacyclovir

Alendronate

New drugs—reports of new drugs recently approved by the FDA lamivudine

New ring systems from 1,2-benzisothiazole-1,1-dioxides and related compounds

A practical asymmetric synthesis of a novel topically active carbonic anhydrase inhibitor

Stereocontrolled addition of propionate homoenolate equivalents to chiral α-amino aldehydes

1-CHLORO-(2S,3S)-DIHYDROXYCYCLOHEXA-4,6-DIENE

プロセス化学の展開(オピニオン,<特集>医薬プロセスケミストリーの新世紀)

Asymmetric bioreduction of cyclohexylphenyl ketone to its corresponding alcohol (+) cyclohexylphenyl alcohol by the yeast Candida magnoliae MY 1785

Spirodioxolane intermediates in the reaction of 2-(trimethylsilyl)thiazole with aldehydes. Support for the 2-ylide mechanism

Synthesis of PAF antagonist MK-287

A stereoselective synthesis of a key 1β-methylcarbapenem intermediate via a diastereoselective decarboxylation

Regional Management and e-Democracy in the Information Society: Communications among Citizens and Officials on the Website Provided by Local Governments for Good Local Management

Stereocontrolled addition of chiral, non-racemic amide homoenolates to t-Boc-(S)-phenylalaninal

Diastereoselective routes to a 1β-methylcarbapenem key intermediate. Scope of ate complex formation between ester enolates and organoboranes and- alanes

A facially-selective protonation controls the stereochemistry of a key intermediate in the synthesis of 1β-methylcarbapenems

An Unusual Stereoselective Decarboxylation: A Key Reaction to an Important Intermediate for Carbapenem Antibiotics

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