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G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells

Oncogene, 2006-03, Vol.25 (13), p.1955-1966

2006

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Effect on Tumor Cells of Blocking Survival Response to Glucose Deprivation

JNCI : Journal of the National Cancer Institute, 2004-09, Vol.96 (17), p.1300-1310

2004

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Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells

European journal of cancer (1990), 2005-12, Vol.41 (18), p.2873-2881

2005

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Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin : in vitro and in vivo studies in acute leukemia

Oncogene, 2006-09, Vol.25 (42), p.5719-5725

2006

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Telomestatin, a Novel Telomerase Inhibitor from Streptomyces anulatus

Journal of the American Chemical Society, 2001-02, Vol.123 (6), p.1262-1263

2001

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Studying telomere replication by Q-CO-FISH: the effect of telomestatin, a potent G-quadruplex ligand

Cytogenetic and genome research, 2008-01, Vol.122 (3-4), p.229-236

2008

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Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin

Toxicon (Oxford), 2009-05, Vol.53 (6), p.680-684

2009

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LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells

Blood, 2020-08, Vol.136 (6), p.684-697

2020

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A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis

The Journal of biological chemistry, 2017-12, Vol.292 (49), p.20076-20085

2017

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Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase

Cancer research (Chicago, Ill.), 2003-10, Vol.63 (19), p.6149-6153

2003

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Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (44), p.17347-17352

2007

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A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia

International journal of oncology, 2004-06, Vol.24 (6), p.1481

2004

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Identification of a chemical modulator of EZH2-mediated silencing by cell-based high-throughput screening assay

Journal of biochemistry (Tokyo), 2019-07, Vol.166 (1), p.41-50

2019

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Structure of Apoptolidin, a Specific Apoptosis Inducer in Transformed Cells

Journal of the American Chemical Society, 1998-04, Vol.120 (14), p.3524-3525

1998

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Experimental Evidence for Intramolecular Blue-Shifting C−H···O Hydrogen Bonding by Matrix-Isolation Infrared Spectroscopy

Journal of the American Chemical Society, 2003-11, Vol.125 (46), p.13910-13911

2003

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Novel terpenes generated by heterologous expression of bacterial terpene synthase genes in an engineered Streptomyces host

Journal of antibiotics, 2015-06, Vol.68 (6), p.385-394

2015

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Design and Synthesis of an Expanded Porphyrin That Has Selectivity for the c-MYC G-Quadruplex Structure

Journal of the American Chemical Society, 2005-03, Vol.127 (9), p.2944-2959

2005

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Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways

Oncogene, 2003-08, Vol.22 (34), p.5338-5347

2003

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Asymmetric Total Synthesis of ent-PyripyropeneA

Chemistry : a European journal, 2015-06, Vol.21 (26), p.9454-9460

2015

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Apoptolidin, a New Apoptosis Inducer in Transformed Cells from Nocardiopsis sp

The Journal of Antibiotics, 1997/07/25, Vol.50(7), pp.628-630

1997

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G-quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer

Nucleic Acids Symposium Series, 2009-09, Vol.53 (1), p.233-234

2009

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Interaction of Telomestatin with the Telomeric Single-strand Overhang

The Journal of biological chemistry, 2004-10, Vol.279 (40), p.41487-41494

2004

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Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry

Chemical communications (Cambridge, England), 2003-11 (21), p.2702-2703

2003

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Selective Cytotoxicity and Stereochemistry of Aspochalasin D

The Journal of Antibiotics, 2001/04/25, Vol.54(4), pp.379-381

2001

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Structure of thioviridamide, a novel apoptosis inducer from Streptomyces olivoviridis

Journal of antibiotics, 2006-01, Vol.59 (1), p.6-10

2006

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G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells

Effect on Tumor Cells of Blocking Survival Response to Glucose Deprivation

Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells

Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin : in vitro and in vivo studies in acute leukemia

Telomestatin, a Novel Telomerase Inhibitor from Streptomyces anulatus

Studying telomere replication by Q-CO-FISH: the effect of telomestatin, a potent G-quadruplex ligand

Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin

LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells

A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis

Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase

Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia

Identification of a chemical modulator of EZH2-mediated silencing by cell-based high-throughput screening assay

Structure of Apoptolidin, a Specific Apoptosis Inducer in Transformed Cells

Experimental Evidence for Intramolecular Blue-Shifting C−H···O Hydrogen Bonding by Matrix-Isolation Infrared Spectroscopy

Novel terpenes generated by heterologous expression of bacterial terpene synthase genes in an engineered Streptomyces host

Design and Synthesis of an Expanded Porphyrin That Has Selectivity for the c-MYC G-Quadruplex Structure

Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways

Asymmetric Total Synthesis of ent-PyripyropeneA

Apoptolidin, a New Apoptosis Inducer in Transformed Cells from Nocardiopsis sp

G-quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer

Interaction of Telomestatin with the Telomeric Single-strand Overhang

Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry

Selective Cytotoxicity and Stereochemistry of Aspochalasin D

Structure of thioviridamide, a novel apoptosis inducer from Streptomyces olivoviridis

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