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Polyamine Control of Translation Elongation Regulates Start Site Selection on Antizyme Inhibitor mRNA via Ribosome Queuing

Molecular cell, 2018-04, Vol.70 (2), p.254-264.e6

2018

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The hypusine-containing translation factor eIF5A

Critical reviews in biochemistry and molecular biology, 2014-09, Vol.49 (5), p.413-425

2014

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Molecular insights into protein synthesis with proline residues

EMBO reports, 2016-12, Vol.17 (12), p.1776-1784

2016

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Structural characterization of ribosome recruitment and translocation by type IV IRES

eLife, 2016-05, Vol.5

2016

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Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis

Nucleic acids research, 2017-08, Vol.45 (14), p.8392-8402

2017

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Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex

Nature communications, 2020-10, Vol.11 (1), p.5003-5003, Article 5003

2020

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Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome

Journal of molecular biology, 2016-09, Vol.428 (18), p.3570-3576

2016

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Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation

Cell, 2022-11, Vol.185 (24), p.4474-4487.e17

2022

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eIF5A Promotes Translation of Polyproline Motifs

Molecular cell, 2013-07, Vol.51 (1), p.35-45

2013

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eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity

Nucleic acids research, 2023-07, Vol.51 (13), p.6899-6913

2023

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Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (11), p.E2126-E2135

2017

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eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining

Nature (London), 2022-07, Vol.607 (7917), p.185-190

2022

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Interaction between 25S rRNA A Loop and Eukaryotic Translation Initiation Factor 5B Promotes Subunit Joining and Ensures Stringent AUG Selection

Molecular and Cellular Biology, 2013-09, Vol.33 (18), p.3540-3548

2013

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Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control

The EMBO journal, 2004-03, Vol.23 (5), p.1166-1177

2004

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Interaction between Eukaryotic Initiation Factors 1A and 5B Is Required for Efficient Ribosomal Subunit Joining

The Journal of biological chemistry, 2006-03, Vol.281 (13), p.8469-8475

2006

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Translational autoregulation of the S. cerevisiae high-affinity polyamine transporter Hol1

Molecular cell, 2021-10, Vol.81 (19), p.3904-3918.e6

2021

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rRNA Suppressor of a Eukaryotic Translation Initiation Factor 5B/Initiation Factor 2 Mutant Reveals a Binding Site for Translational GTPases on the Small Ribosomal Subunit

Molecular and Cellular Biology, 2009-02, Vol.29 (3), p.808-821

2009

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Conformational changes in the P site and mRNA entry channel evoked by AUG recognition in yeast translation preinitiation complexes

Nucleic acids research, 2015-02, Vol.43 (4), p.2293-2312

2015

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Initiation Factor eIF5B Catalyzes Second GTP-Dependent Step in Eukaryotic Translation Initiation

Proceedings of the National Academy of Sciences - PNAS, 2002-12, Vol.99 (26), p.16689-16694

2002

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eIF2γ Mutation that Disrupts eIF2 Complex Integrity Links Intellectual Disability to Impaired Translation Initiation

Molecular cell, 2012-11, Vol.48 (4), p.641-646

2012

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Kinetic Analysis of Late Steps of Eukaryotic Translation Initiation

Journal of molecular biology, 2009-01, Vol.385 (2), p.491-506

2009

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Intragenic Suppressor Mutations Restore GTPase and Translation Functions of a Eukaryotic Initiation Factor 5B Switch II Mutant

Molecular and Cellular Biology, 2007-03, Vol.27 (5), p.1677-1685

2007

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Molecular Genetic Structure–Function Analysis of Translation Initiation Factor eIF5B

Methods in Enzymology, 2007, Vol.429, p.185-201

2007

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An Ire1–Phk1 Chimera Reveals a Dispensable Role of Autokinase Activity in Endoplasmic Reticulum Stress Response

Journal of molecular biology, 2013-06, Vol.425 (12), p.2083-2099

2013

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Polyamine Control of Translation Elongation Regulates Start Site Selection on Antizyme Inhibitor mRNA via Ribosome Queuing

The hypusine-containing translation factor eIF5A

Molecular insights into protein synthesis with proline residues

Structural characterization of ribosome recruitment and translocation by type IV IRES

Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis

Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex

Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome

EIF2S3 Mutations Associated with Severe X‐Linked Intellectual Disability Syndrome MEHMO

Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation

eIF5A Promotes Translation of Polyproline Motifs

eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity

Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons

eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining

Interaction between 25S rRNA A Loop and Eukaryotic Translation Initiation Factor 5B Promotes Subunit Joining and Ensures Stringent AUG Selection

Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control

Interaction between Eukaryotic Initiation Factors 1A and 5B Is Required for Efficient Ribosomal Subunit Joining

Translational autoregulation of the S. cerevisiae high-affinity polyamine transporter Hol1

rRNA Suppressor of a Eukaryotic Translation Initiation Factor 5B/Initiation Factor 2 Mutant Reveals a Binding Site for Translational GTPases on the Small Ribosomal Subunit

Conformational changes in the P site and mRNA entry channel evoked by AUG recognition in yeast translation preinitiation complexes

Initiation Factor eIF5B Catalyzes Second GTP-Dependent Step in Eukaryotic Translation Initiation

eIF2γ Mutation that Disrupts eIF2 Complex Integrity Links Intellectual Disability to Impaired Translation Initiation

Kinetic Analysis of Late Steps of Eukaryotic Translation Initiation

Intragenic Suppressor Mutations Restore GTPase and Translation Functions of a Eukaryotic Initiation Factor 5B Switch II Mutant

Molecular Genetic Structure–Function Analysis of Translation Initiation Factor eIF5B

An Ire1–Phk1 Chimera Reveals a Dispensable Role of Autokinase Activity in Endoplasmic Reticulum Stress Response

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