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The Reverse Activity of Human Acid Ceramidase

The Journal of biological chemistry, 2003-08, Vol.278 (32), p.29948-29953

2003

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Cancer and sphingolipid storage disease therapy using novel synthetic analogs of sphingolipids

Chemistry and physics of lipids, 2012-05, Vol.165 (4), p.462-474

2012

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A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann–Pick disease

Analytical biochemistry, 2003-03, Vol.314 (1), p.116-120

2003

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lipid analogue that inhibits sphingomyelin hydrolysis and synthesis, increases ceramide, and leads to cell death

Journal of lipid research, 2005-11, Vol.46 (11), p.2315-2324

2005

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Characterization of human acid sphingomyelinase purified from the media of overexpressing Chinese hamster ovary cells

Biochimica et biophysica acta, 1999-07, Vol.1432 (2), p.251-264

1999

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Anti-Plasmodium activity of ceramide analogs

Malaria journal, 2004-12, Vol.3 (1), p.49-49

2004

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Cloning and Characterization of the Full-Length cDNA and Genomic Sequences Encoding Murine Acid Ceramidase

Genomics (San Diego, Calif.), 1998-06, Vol.50 (2), p.267-274

1998

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The novel sphingosine-1-phosphate receptors antagonist AD2900 affects lymphocyte activation and inhibits T-cell entry into the lymph nodes

Oncotarget, 2017-08, Vol.8 (32), p.53563-53580

2017

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Purification and Characterization of Recombinant, Human Acid Ceramidase

The Journal of biological chemistry, 2003-08, Vol.278 (35), p.32978-32986

2003

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Importance of splicing for prosaposin sorting

Biochemical journal, 1999-02, Vol.337 ( Pt 3) (3), p.433-443

1999

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Simultaneous quantitative analysis of ceramide and sphingosine in mouse blood by naphthalene-2,3-dicarboxyaldehyde derivatization after hydrolysis with ceramidase

Analytical biochemistry, 2005-05, Vol.340 (1), p.113-122

2005

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Purification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinase

The Journal of biological chemistry, 2003-08, Vol.278 (35), p.32978-32986

2003

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Synthetic, non-natural sphingolipid analogs inhibit the biosynthesis of cellular sphingolipids, elevate ceramide and induce apoptotic cell death

Biochimica et biophysica acta, 2003-09, Vol.1633 (3), p.161-169

2003

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Synthetic, Non-Natural Analogs of Ceramide Elevate Cellular Ceramide, Inducing Apoptotic Death to Prostate Cancer Cells and Eradicating Tumors in Mice

Cancer investigation, 2010-05, Vol.28 (5), p.535-543

2010

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Infusion of recombinant human acid sphingomyelinase into Niemann‐Pick disease mice leads to visceral, but not neurological, correction of the pathophysiology

The FASEB journal, 2000-10, Vol.14 (13), p.1988-1995

2000

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Sperm Abnormalities in Heterozygous Acid Sphingomyelinase Knockout Mice Reveal a Novel Approach for the Prevention of Genetic Diseases

The American journal of pathology, 2007-06, Vol.170 (6), p.2077-2088

2007

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Reproductive Pathology and Sperm Physiology in Acid Sphingomyelinase-Deficient Mice

The American journal of pathology, 2002-09, Vol.161 (3), p.1061-1075

2002

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Studies of sphingomyelin and sphingomyelinases

Chemistry and physics of lipids, 1999-11, Vol.102 (1), p.45-53

Gatt, Shimon

1999

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Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue

FEBS letters, 1998-04, Vol.426 (1), p.102-106

1998

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Liposome-mediated, fluorescence-based studies of sphingolipid metabolism in intact cells

Methods in molecular biology (Clifton, N.J.), 2002, Vol.199, p.85

2002

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Use of fluorescent substrates for characterization of Gaucher disease mutations

Blood cells, molecules, & diseases, 2005-07, Vol.35 (1), p.57-65

2005

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Enzymatic Hydrolysis of Sphingolipids

The Journal of biological chemistry, 1966-08, Vol.241 (16), p.3724-3730

Gatt, Shimon

1966

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Clonal analysis of the response of human promyelocytic leukemia (HL-60) cells to photosensitization induced by a pyrene-containing fatty acid

Leukemia research, 1987, Vol.11 (11), p.1019-1026

1987

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An Enzymatic Assay for Quantifying Sphingomyelin in Tissues and Plasma from Humans and Mice with Niemann–Pick Disease

Analytical biochemistry, 2001-06, Vol.293 (2), p.204-211

2001

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Bone Marrow Transplantation in Acid Sphingomyelinase-Deficient Mice: Engraftment and Cell Migration Into the Brain as a Function of Radiation, Age, and Phenotype

Blood, 1997-07, Vol.90 (1), p.444-452

1997

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The Reverse Activity of Human Acid Ceramidase

Cancer and sphingolipid storage disease therapy using novel synthetic analogs of sphingolipids

A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann–Pick disease

lipid analogue that inhibits sphingomyelin hydrolysis and synthesis, increases ceramide, and leads to cell death

Characterization of human acid sphingomyelinase purified from the media of overexpressing Chinese hamster ovary cells

Anti-Plasmodium activity of ceramide analogs

Cloning and Characterization of the Full-Length cDNA and Genomic Sequences Encoding Murine Acid Ceramidase

The novel sphingosine-1-phosphate receptors antagonist AD2900 affects lymphocyte activation and inhibits T-cell entry into the lymph nodes

Purification and Characterization of Recombinant, Human Acid Ceramidase

Importance of splicing for prosaposin sorting

Simultaneous quantitative analysis of ceramide and sphingosine in mouse blood by naphthalene-2,3-dicarboxyaldehyde derivatization after hydrolysis with ceramidase

Purification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinase

Synthetic, non-natural sphingolipid analogs inhibit the biosynthesis of cellular sphingolipids, elevate ceramide and induce apoptotic cell death

Synthetic, Non-Natural Analogs of Ceramide Elevate Cellular Ceramide, Inducing Apoptotic Death to Prostate Cancer Cells and Eradicating Tumors in Mice

Infusion of recombinant human acid sphingomyelinase into Niemann‐Pick disease mice leads to visceral, but not neurological, correction of the pathophysiology

Sperm Abnormalities in Heterozygous Acid Sphingomyelinase Knockout Mice Reveal a Novel Approach for the Prevention of Genetic Diseases

Reproductive Pathology and Sperm Physiology in Acid Sphingomyelinase-Deficient Mice

Studies of sphingomyelin and sphingomyelinases

Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue

Liposome-mediated, fluorescence-based studies of sphingolipid metabolism in intact cells

Use of fluorescent substrates for characterization of Gaucher disease mutations

Enzymatic Hydrolysis of Sphingolipids

Clonal analysis of the response of human promyelocytic leukemia (HL-60) cells to photosensitization induced by a pyrene-containing fatty acid

An Enzymatic Assay for Quantifying Sphingomyelin in Tissues and Plasma from Humans and Mice with Niemann–Pick Disease

Bone Marrow Transplantation in Acid Sphingomyelinase-Deficient Mice: Engraftment and Cell Migration Into the Brain as a Function of Radiation, Age, and Phenotype

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