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Resistance to 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine Derivatives Is Generated by Mutations at Multiple Sites in the HIV-1 Reverse Transcriptase

Virology (New York, N.Y.), 1995-06, Vol.210 (1), p.186-193

1995

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Synthesis and anti-hiv-1 activities of 6-arylthio and 6-arylselenoacyclonucleosides

Journal of heterocyclic chemistry, 1994-01, Vol.31 (1), p.177-185

1994

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Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor

Clinical cancer research, 1998-05, Vol.4 (5), p.1165-1175

1998

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Synthesis of racemic and enantiomerically pure 2′-thia-2′,3′-dideoxycytidine as potential anti-hepatitis B virus agents

Journal of heterocyclic chemistry, 1997-05, Vol.34 (3), p.909-915

1997

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Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii

Biochemical pharmacology, 1996-06, Vol.51 (12), p.1687-1700

1996

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Synthesis of enantiomers of 2′-aminomethyl-5-benzylacyclouridine (AM-BAU) and 2′-aminomethyl-5-benzyloxybenzylacyclouridine (AM-BBAU). Potent inhibitors of uridine phosphorylase

Journal of heterocyclic chemistry, 1988-09, Vol.25 (5), p.1587-1592

1988

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Synthesis of some halogenated and disubstituted amino benzylacyclouridine derivatives

Journal of heterocyclic chemistry, 1992-07, Vol.29 (4), p.683-689

1992

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Synthesis of 5-benzyl and 5-benzyloxybenzyl-3′-azido-2′,3′-dideoxyuridine and their analogues as potential anti-AIDS agents

Journal of heterocyclic chemistry, 1990-09, Vol.27 (6), p.1569-1574

1990

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Inhibition of nucleoside transport in murine lymphoma L5178Y cells and human erythrocytes by the uridine phosphorylase inhibitors 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine

Cancer research (Chicago, Ill.), 1984-09, Vol.44 (9), p.3744-3748

1984

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Benzylacyclouridine Enhances 5-Fluorouracil Cytotoxicity against Human Prostate Cancer Cell Lines

Pharmacology, 1998-02, Vol.56 (2), p.80-91

1998

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Synthesis of variants of 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine

Journal of heterocyclic chemistry, 1986-11, Vol.23 (6), p.1651-1655

1986

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Differential Effect of Benzylacyclouridine on the Toxic and Therapeutic Effects of Azidothymidine in Mice

Blood, 1990-12, Vol.76 (11), p.2216-2221

1990

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Facile synthesis of 1-.beta.-D-arabinofuranosyl-2-seleno- and-4-selenouracil and related compounds

Journal of organic chemistry, 1975-10, Vol.40 (20), p.2971-2974

1975

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Potentiation of 5-fluoro-2'-deoxyuridine antineoplastic activity by the uridine phosphorylase inhibitors benzylacyclouridine and benzyloxybenzylacyclouridine

Cancer research (Chicago, Ill.), 1984-05, Vol.44 (5), p.1852-1856

1984

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A convenient one-step synthesis of 6-selenoxo-9-(β-D-ribofuranosyl)purine 3′,5′-cyclic phosphate and related compounds

Journal of heterocyclic chemistry, 1975-06, Vol.12 (3), p.493-500

1975

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Action of uracil analogs on human immunodeficiency virus type 1 and its reverse transcriptase

Antimicrobial Agents and Chemotherapy, 1995-02, Vol.39 (2), p.539-541

1995

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New analogues of benzylacyclouridines, specific and potent inhibitors of uridine phosphorylase from human and mouse livers

Biochemical pharmacology, 1987-07, Vol.36 (13), p.2195-2201

1987

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Synthesis and Cytotoxicity of 6-Selenopurine Arabinoside and Related Compounds

Journal of pharmaceutical sciences, 1975-08, Vol.64 (8), p.1343-1346

1975

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Inhibition of nucleoside transport by nitrobenzylthioformycin analogs

Biochemical pharmacology, 1990-08, Vol.40 (3), p.615-619

1990

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Sulfur and selenium compounds related to acetylcholine and choline. 11. Selenocarbonyl ester and selenocarboxamide analogs of local anesthetics

Journal of medicinal chemistry, 1972-07, Vol.15 (7), p.760-762

1972

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Inhibition of uridine phosphorylase from Escherichia coli by benzylacyclouridines

Biochemical pharmacology, 1986-11, Vol.35 (21), p.3853-3855

1986

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The Aminolysis of Thioacyl and Selenoacyl Analogs

Journal of the American Chemical Society, 1963-11, Vol.85 (21), p.3458-3462

1963

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ChemInform Abstract: Synthesis of 5-Halogeno-6-amino-2′-deoxyuridines and Their Analogues as Potential Inhibitors of Thymidine Phosphorylase

ChemInform, 1999-04, Vol.30 (16), p.no-no

1999

Volltextzugriff (PDF)

A new alkylation reagent for seleno- and thio-substituted nucleosides and related compounds

Journal of organic chemistry, 1976-05, Vol.41 (10), p.1847-1848

1976

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Sulfur and selenium compounds related to acetylcholine and choline. X. Acetylthionocholine

Journal of medicinal chemistry, 1970-03, Vol.13 (2), p.214-215

1970

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Resistance to 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine Derivatives Is Generated by Mutations at Multiple Sites in the HIV-1 Reverse Transcriptase

Synthesis and anti-hiv-1 activities of 6-arylthio and 6-arylselenoacyclonucleosides

Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor

Synthesis of racemic and enantiomerically pure 2′-thia-2′,3′-dideoxycytidine as potential anti-hepatitis B virus agents

Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii

Synthesis of enantiomers of 2′-aminomethyl-5-benzylacyclouridine (AM-BAU) and 2′-aminomethyl-5-benzyloxybenzylacyclouridine (AM-BBAU). Potent inhibitors of uridine phosphorylase

Synthesis of some halogenated and disubstituted amino benzylacyclouridine derivatives

Synthesis of 5-benzyl and 5-benzyloxybenzyl-3′-azido-2′,3′-dideoxyuridine and their analogues as potential anti-AIDS agents

Inhibition of nucleoside transport in murine lymphoma L5178Y cells and human erythrocytes by the uridine phosphorylase inhibitors 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine

Benzylacyclouridine Enhances 5-Fluorouracil Cytotoxicity against Human Prostate Cancer Cell Lines

Synthesis of variants of 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine

Differential Effect of Benzylacyclouridine on the Toxic and Therapeutic Effects of Azidothymidine in Mice

Facile synthesis of 1-.beta.-D-arabinofuranosyl-2-seleno- and-4-selenouracil and related compounds

Potentiation of 5-fluoro-2'-deoxyuridine antineoplastic activity by the uridine phosphorylase inhibitors benzylacyclouridine and benzyloxybenzylacyclouridine

A convenient one-step synthesis of 6-selenoxo-9-(β-D-ribofuranosyl)purine 3′,5′-cyclic phosphate and related compounds

Action of uracil analogs on human immunodeficiency virus type 1 and its reverse transcriptase

New analogues of benzylacyclouridines, specific and potent inhibitors of uridine phosphorylase from human and mouse livers

Synthesis and Cytotoxicity of 6-Selenopurine Arabinoside and Related Compounds

Inhibition of nucleoside transport by nitrobenzylthioformycin analogs

Sulfur and selenium compounds related to acetylcholine and choline. 11. Selenocarbonyl ester and selenocarboxamide analogs of local anesthetics

Inhibition of uridine phosphorylase from Escherichia coli by benzylacyclouridines

The Aminolysis of Thioacyl and Selenoacyl Analogs

ChemInform Abstract: Synthesis of 5-Halogeno-6-amino-2′-deoxyuridines and Their Analogues as Potential Inhibitors of Thymidine Phosphorylase

A new alkylation reagent for seleno- and thio-substituted nucleosides and related compounds

Sulfur and selenium compounds related to acetylcholine and choline. X. Acetylthionocholine

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