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MERTK receptor tyrosine kinase is a therapeutic target in melanoma

The Journal of clinical investigation, 2013-05, Vol.123 (5), p.2257-2267

2013

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Vascular channels formed by subpopulations of PECAM1+ melanoma cells

Nature communications, 2014-10, Vol.5 (1), p.5200-5200, Article 5200

2014

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Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032

Radiotherapy and oncology, 2011-03, Vol.98 (3), p.394-399

2011

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Vascular channels formed by subpopulations of PECAM1+ melanoma cells

Nature communications, 2014-10, Vol.5, p.5200-5200

2014

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RKIP downregulates B-Raf kinase activity in melanoma cancer cells

Oncogene, 2005-05, Vol.24 (21), p.3535-3540

2005

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Radiosensitization of Epidermal Growth Factor Receptor/HER2–Positive Pancreatic Cancer Is Mediated by Inhibition of Akt Independent of Ras Mutational Status

Clinical cancer research, 2010-02, Vol.16 (3), p.912-923

2010

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Similar Nucleotide Excision Repair Capacity in Melanocytes and Melanoma Cells

Cancer research (Chicago, Ill.), 2010-06, Vol.70 (12), p.4922-4930

2010

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Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf > MEK > ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK

Radiotherapy and oncology, 2009-12, Vol.93 (3), p.639-644

2009

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Loss of Transgelin in Breast and Colon Tumors and in RIE-1 Cells by Ras Deregulation of Gene Expression through Raf-independent Pathways

The Journal of biological chemistry, 2002-03, Vol.277 (12), p.9790-9799

2002

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Lapatinib in Combination With Radiation Diminishes Tumor Regrowth in HER2+ and Basal-Like/EGFR+ Breast Tumor Xenografts

International journal of radiation oncology, biology, physics, 2010-06, Vol.77 (2), p.575-581

2010

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CD200 is induced by ERK and is a potential therapeutic target in melanoma

The Journal of clinical investigation, 2007-12, Vol.117 (12), p.3922-3929

2007

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Targeted next generation sequencing identifies clinically actionable mutations in patients with melanoma

Pigment cell and melanoma research, 2014-07, Vol.27 (4), p.653-663

2014

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Ras-mediated Loss of the Pro-apoptotic Response Protein Par-4 Is Mediated by DNA Hypermethylation through Raf-independent and Raf-dependent Signaling Cascades in Epithelial Cells

The Journal of biological chemistry, 2005-06, Vol.280 (24), p.23363-23370

2005

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Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling

The Journal of biological chemistry, 2004-08, Vol.279 (32), p.33168-33176

2004

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Development of DNA Damage Response Signaling Biomarkers using Automated, Quantitative Image Analysis

The journal of histochemistry and cytochemistry, 2014-03, Vol.62 (3), p.185-196

2014

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Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma

Cancer research (Chicago, Ill.), 2007-02, Vol.67 (4), p.1502-1512

2007

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Mechanisms of chromosomal instability in melanoma

Environmental and molecular mutagenesis, 2014-07, Vol.55 (6), p.457-471

2014

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Phase I Study and Biomarker Analysis of Lapatinib and Concurrent Radiation for Locally Advanced Breast Cancer

The oncologist (Dayton, Ohio), 2012-12, Vol.17 (12), p.1496-1503

2012

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Defective Cell Cycle Checkpoint Functions in Melanoma Are Associated with Altered Patterns of Gene Expression

Journal of investigative dermatology, 2008-01, Vol.128 (1), p.175-187

2008

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A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines

Pigment cell and melanoma research, 2012-07, Vol.25 (4), p.514-526

2012

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Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth

Molecular cancer therapeutics, 2007-08, Vol.6 (8), p.2220-2229

2007

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Identification and Characterization of a Gene Encoding a Gut-enriched Krüppel-like Factor Expressed during Growth Arrest

The Journal of biological chemistry, 1996-08, Vol.271 (33), p.20009-20017

1996

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Opposing Roles of the Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Cascades in Ras-Mediated Downregulation of Tropomyosin

Molecular and Cellular Biology, 2002-04, Vol.22 (7), p.2304-2317

2002

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Expression of the gut-enriched Krüppel-like factor gene during development and intestinal tumorigenesis

FEBS letters, 1997-12, Vol.419 (2), p.239-243

1997

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Size-dependent increase in prostanoid levels in adenomas of patients with familial adenomatous polyposis

Cancer research (Chicago, Ill.), 1998-04, Vol.58 (8), p.1750-1753

1998

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MERTK receptor tyrosine kinase is a therapeutic target in melanoma

Vascular channels formed by subpopulations of PECAM1+ melanoma cells

Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032

Vascular channels formed by subpopulations of PECAM1+ melanoma cells

RKIP downregulates B-Raf kinase activity in melanoma cancer cells

Radiosensitization of Epidermal Growth Factor Receptor/HER2–Positive Pancreatic Cancer Is Mediated by Inhibition of Akt Independent of Ras Mutational Status

Similar Nucleotide Excision Repair Capacity in Melanocytes and Melanoma Cells

Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf > MEK > ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK

Loss of Transgelin in Breast and Colon Tumors and in RIE-1 Cells by Ras Deregulation of Gene Expression through Raf-independent Pathways

Lapatinib in Combination With Radiation Diminishes Tumor Regrowth in HER2+ and Basal-Like/EGFR+ Breast Tumor Xenografts

CD200 is induced by ERK and is a potential therapeutic target in melanoma

Targeted next generation sequencing identifies clinically actionable mutations in patients with melanoma

Ras-mediated Loss of the Pro-apoptotic Response Protein Par-4 Is Mediated by DNA Hypermethylation through Raf-independent and Raf-dependent Signaling Cascades in Epithelial Cells

Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling

Development of DNA Damage Response Signaling Biomarkers using Automated, Quantitative Image Analysis

Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma

Mechanisms of chromosomal instability in melanoma

Phase I Study and Biomarker Analysis of Lapatinib and Concurrent Radiation for Locally Advanced Breast Cancer

Defective Cell Cycle Checkpoint Functions in Melanoma Are Associated with Altered Patterns of Gene Expression

A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines

Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth

Identification and Characterization of a Gene Encoding a Gut-enriched Krüppel-like Factor Expressed during Growth Arrest

Opposing Roles of the Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Cascades in Ras-Mediated Downregulation of Tropomyosin

Expression of the gut-enriched Krüppel-like factor gene during development and intestinal tumorigenesis

Size-dependent increase in prostanoid levels in adenomas of patients with familial adenomatous polyposis

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