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Structural Reorganization of the Toll-Like Receptor 8 Dimer Induced by Agonistic Ligands

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6126), p.1426-1429

2013

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Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology

Immunological reviews, 2016-01, Vol.269 (1), p.60-75

2016

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Crystal structure of NOD2 and its implications in human disease

Nature communications, 2016-06, Vol.7 (1), p.11813-11813, Article 11813

2016

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Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

Nature (London), 2015-04, Vol.520 (7549), p.702-705

2015

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Mechanisms controlling nucleic acid-sensing Toll-like receptors

International immunology, 2018-03, Vol.30 (2), p.43-51

2018

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Emerging roles of the processing of nucleic acids and Toll‐like receptors in innate immune responses to nucleic acids

Journal of leukocyte biology, 2017-01, Vol.101 (1), p.135-142

2017

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Guanosine and its modified derivatives are endogenous ligands for TLR7

International immunology, 2016-05, Vol.28 (5), p.211-222

2016

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Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands

Cell reports (Cambridge), 2018-12, Vol.25 (12), p.3371-3381.e5

2018

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TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction

Nature communications, 2023-01, Vol.14 (1), p.164-164, Article 164

2023

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Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages

International immunology, 2021-09, Vol.33 (9), p.479-490

2021

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Dynamic control of nucleic-acid-sensing Toll-like receptors by the endosomal compartment

International immunology, 2021-12, Vol.33 (12), p.835-840

2021

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The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages

International immunology, 2020-12, Vol.32 (12), p.785-798

2020

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Structural analysis reveals TLR7 dynamics underlying antagonism

Nature communications, 2020-10, Vol.11 (1), p.5204-5204, Article 5204

2020

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Activated M2 Macrophages Contribute to the Pathogenesis of IgG4‐Related Disease via Toll‐like Receptor 7/Interleukin‐33 Signaling

Arthritis & rheumatology (Hoboken, N.J.), 2020-01, Vol.72 (1), p.166-178

2020

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Structural basis for species‐specific activation of mouse Toll‐like receptor 9

FEBS letters, 2018-08, Vol.592 (15), p.2636-2646

2018

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Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment

Frontiers in immunology, 2022-06, Vol.13, p.941931-941931

2022

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Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (11), p.3012-3017

2016

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Numerical simulation of iron oxide concretions on Earth and Mars through calcite dissolution

Geochimica et cosmochimica acta, 2021-02, Vol.295, p.194-206

2021

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Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

Immunity (Cambridge, Mass.), 2011-07, Vol.35 (1), p.69-81

2011

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TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells

Nature communications, 2017-11, Vol.8 (1), p.1592-12, Article 1592

2017

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Derivation and Flight Test Validation of Maximum Rate of Climb during Takeoff for Fixed-Wing UAV Driven by Propeller Engine

Aerospace, 2024-03, Vol.11 (3), p.233

2024

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Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors

Journal of leukocyte biology, 2019-10, Vol.106 (4), p.853-862

2019

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Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs

International immunology, 2019-03, Vol.31 (3), p.167-173

2019

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Requirement of glycosylation machinery in TLR responses revealed by CRISPR/Cas9 screening

International immunology, 2017-08, Vol.29 (8), p.347-355

2017

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Roles of the cleaved N-terminal TLR3 fragment and cell surface TLR3 in double-stranded RNA sensing

The Journal of immunology (1950), 2014-11, Vol.193 (10), p.5208-5217

2014

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Structural Reorganization of the Toll-Like Receptor 8 Dimer Induced by Agonistic Ligands

Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology

Crystal structure of NOD2 and its implications in human disease

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

Mechanisms controlling nucleic acid-sensing Toll-like receptors

Emerging roles of the processing of nucleic acids and Toll‐like receptors in innate immune responses to nucleic acids

Guanosine and its modified derivatives are endogenous ligands for TLR7

Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands

TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction

Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages

Dynamic control of nucleic-acid-sensing Toll-like receptors by the endosomal compartment

The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages

Structural analysis reveals TLR7 dynamics underlying antagonism

Activated M2 Macrophages Contribute to the Pathogenesis of IgG4‐Related Disease via Toll‐like Receptor 7/Interleukin‐33 Signaling

Structural basis for species‐specific activation of mouse Toll‐like receptor 9

Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment

Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8

Numerical simulation of iron oxide concretions on Earth and Mars through calcite dissolution

Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells

Derivation and Flight Test Validation of Maximum Rate of Climb during Takeoff for Fixed-Wing UAV Driven by Propeller Engine

Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors

Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs

Requirement of glycosylation machinery in TLR responses revealed by CRISPR/Cas9 screening

Roles of the cleaved N-terminal TLR3 fragment and cell surface TLR3 in double-stranded RNA sensing

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