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Design, Synthesis and Biological Evaluation of the Quinazoline Derivatives as L858R/T790M/C797S Triple Mutant Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Chemical and Pharmaceutical Bulletin, 2020/10/01, Vol.68(10), pp.971-980

2020

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Design, synthesis, SAR discussion, in vitro and in vivo evaluation of novel selective EGFR modulator to inhibit L858R/T790M double mutants

European journal of medicinal chemistry, 2017-07, Vol.135, p.12-23

2017

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KPT‐330 and Y219 exert a synergistic antitumor effect in triple‐negative breast cancer through inhibiting NF‐κB signaling

FEBS open bio, 2023-04, Vol.13 (4), p.751-762

2023

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Abstract 7271: Proteasome inhibitor FHND6091: A potent therapeutic candidate for PTEN -deficient cholangiocarcinoma

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.7271-7271

2024

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Co-delivery of paclitaxel and gemcitabine via a self-assembling nanoparticle for targeted treatment of breast cancer

RSC advances, 2019-02, Vol.9 (10), p.5512-5520

2019

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Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies

Bioorganic & medicinal chemistry, 2018-08, Vol.26 (14), p.3975-3981

2018

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Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors

Bioorganic & medicinal chemistry, 2019-09, Vol.27 (18), p.4151-4162

2019

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3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies

Bioorganic & medicinal chemistry, 2016-06, Vol.24 (11), p.2576-2588

2016

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Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed from alpha alpha - and alpha beta -amino acids

Bioorganic & medicinal chemistry letters, 2016-04, Vol.26 (8), p.1958-1962

2016

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Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed from αα- and αβ-amino acids

Bioorganic & medicinal chemistry letters, 2016-04, Vol.26 (8), p.1958-1962

2016

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Preclinical Pharmacokinetics, Tissue Distribution and in vitro Metabolism of FHND6091, a Novel Oral Proteasome Inhibitor

Drug design, development and therapy, 2022-01, Vol.16, p.3087-3107

2022

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Co-delivery of paclitaxel and gemcitabine via a self-assembling nanoparticle for targeted treatment of breast cancerElectronic supplementary information (ESI) available. See DOI: 10.1039/c9ra00276f

2019-02

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Estimation of photosynthetically active radiation using solar radiation in the UV–visible spectral band

Solar energy, 2017-09, Vol.153, p.611-622

2017

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WiVi-GR: Wireless-Visual Joint Representation Based Accurate Gesture Recognition

IEEE internet of things journal, 2024-01, Vol.11 (2), p.1-1

2024

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Data‐Independent Acquisition‐Based Quantitative Proteomics Analysis Reveals Dynamic Network Profiles during the Macrophage Inflammatory Response

Proteomics (Weinheim), 2020-01, Vol.20 (2), p.e1900203-n/a

2020

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Performance characteristics and bacterial community analysis of a novel two-step-feed three-stage A/O-MBBR system for nitrogen removal in municipal wastewater

Journal of water process engineering, 2023-04, Vol.52, p.103513, Article 103513

2023

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Modification of the SUNFLUX Solar Radiation Scheme with a New Aerosol Parameterization and Its Validation Using Observation Network Data

Advances in atmospheric sciences, 2017-11, Vol.34 (11), p.1301-1315

2017

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Front Cover: Data‐Independent Acquisition‐Based Quantitative Proteomics Analysis Reveals Dynamic Network Profiles during the Macrophage Inflammatory Response

Proteomics (Weinheim), 2020-01, Vol.20 (2), p.n/a

2020

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Color image denoising based on Gaussian weighting and manifold for high fidelity: Color image denoising based on Gaussian weighting and manifold for high fidelity

Journal of Computer Applications, 2013-11, Vol.33 (9), p.2588-2891

2013

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Electrochemical Reductive Dehalogenation of ortho-Halogenated Phenols on Ag Electrode by in situ FTIR

Asian journal of chemistry, 2014, Vol.26 (13), p.3879-3882

2014

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Patch-Based Cascade Forest Wetland Classification Based on Multi-Temporal SAR Images in Yellow River Delta

IGARSS 2024 - 2024 IEEE International Geoscience and Remote Sensing Symposium, 2024, p.4771-4774

2024

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Design, Synthesis and Biological Evaluation of the Quinazoline Derivatives as L858R/T790M/C797S Triple Mutant Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Design, synthesis, SAR discussion, in vitro and in vivo evaluation of novel selective EGFR modulator to inhibit L858R/T790M double mutants

KPT‐330 and Y219 exert a synergistic antitumor effect in triple‐negative breast cancer through inhibiting NF‐κB signaling

Abstract 7271: Proteasome inhibitor FHND6091: A potent therapeutic candidate for PTEN -deficient cholangiocarcinoma

Co-delivery of paclitaxel and gemcitabine via a self-assembling nanoparticle for targeted treatment of breast cancer

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies

Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors

3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies

Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed from alpha alpha - and alpha beta -amino acids

Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed from αα- and αβ-amino acids

Preclinical Pharmacokinetics, Tissue Distribution and in vitro Metabolism of FHND6091, a Novel Oral Proteasome Inhibitor

Co-delivery of paclitaxel and gemcitabine via a self-assembling nanoparticle for targeted treatment of breast cancerElectronic supplementary information (ESI) available. See DOI: 10.1039/c9ra00276f

Estimation of photosynthetically active radiation using solar radiation in the UV–visible spectral band

WiVi-GR: Wireless-Visual Joint Representation Based Accurate Gesture Recognition

Data‐Independent Acquisition‐Based Quantitative Proteomics Analysis Reveals Dynamic Network Profiles during the Macrophage Inflammatory Response

Performance characteristics and bacterial community analysis of a novel two-step-feed three-stage A/O-MBBR system for nitrogen removal in municipal wastewater

Modification of the SUNFLUX Solar Radiation Scheme with a New Aerosol Parameterization and Its Validation Using Observation Network Data

Front Cover: Data‐Independent Acquisition‐Based Quantitative Proteomics Analysis Reveals Dynamic Network Profiles during the Macrophage Inflammatory Response

Color image denoising based on Gaussian weighting and manifold for high fidelity: Color image denoising based on Gaussian weighting and manifold for high fidelity

Electrochemical Reductive Dehalogenation of ortho-Halogenated Phenols on Ag Electrode by in situ FTIR

Patch-Based Cascade Forest Wetland Classification Based on Multi-Temporal SAR Images in Yellow River Delta

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