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Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat

Diabetologia, 2008-12, Vol.51 (12), p.2309-2317

2008

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Caffeine and theophylline block insulin-stimulated glucose uptake and PKB phosphorylation in rat skeletal muscles

Acta Physiologica, 2010-09, Vol.200 (1), p.65-74

2010

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Clozapine directly increases insulin and glucagon secretion from islets: Implications for impairment of glucose tolerance

Schizophrenia research, 2014-08, Vol.157 (1), p.128-133

2014

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Dietary supplementation of clinically utilized PI3K p110α inhibitor extends the lifespan of male and female mice

Nature aging, 2023-02, Vol.3 (2), p.162-172

2023

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The activation of the Akt/PKB signalling pathway in the brains of clozapine-exposed rats is linked to hyperinsulinemia and not a direct drug effect

Psychopharmacology, 2014-12, Vol.231 (23), p.4553-4560

2014

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Olanzapine effects on body composition, food preference, glucose metabolism and insulin sensitivity in the rat

Archives of physiology and biochemistry, 2011-10, Vol.117 (4), p.241-249

2011

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Mechanisms regulating phosphoinositide 3-kinase signalling in insulin-sensitive tissues

Acta physiologica Scandinavica, 2005-01, Vol.183 (1), p.3-12

Shepherd, P. R.

2005

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Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue

The Journal of biological chemistry, 1993-10, Vol.268 (30), p.22243-22246

1993

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Saturated-fat diet induces moderate diabetes and severe glomerulosclerosis in hamsters

Diabetologia, 2003-10, Vol.46 (10), p.1408-1418

2003

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Glucose Transporters and Insulin Action — Implications for Insulin Resistance and Diabetes Mellitus

The New England journal of medicine, 1999-07, Vol.341 (4), p.248-257

1999

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Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes

American journal of physiology: endocrinology and metabolism, 1997-07, Vol.273 (1), p.E46-E51

1997

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Altered adipocyte properties in the offspring of protein malnourished rats

British journal of nutrition, 1997-07, Vol.78 (1), p.121-129

1997

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Microwave Devices, Circuits and Subsystems for Communications Engineering

1. Aufl., 2005

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Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

Biochemical journal, 1995-01, Vol.305 ( Pt 1) (1), p.25-28

1995

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Feeding and glucagon‐like peptide ‐1 receptor activation stabilise β‐catenin in specific hypothalamic nuclei in male rats

Journal of neuroendocrinology, 2018-06, Vol.30 (6)

2018

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Growth factor regulation of the novel class II phosphoinositide 3-kinases

Biochemical Society transactions, 2001-08, Vol.29 (Pt 4), p.535-537

2001

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Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation

Biochemical journal, 1999-12, Vol.344 (2), p.427-431

1999

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Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

Biochemical journal, 1998-08, Vol.333 ( Pt 3) (3), p.471-490

1998

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TNF-alpha and leptin activate the alpha-isoform of class II phosphoinositide 3-kinase

Biochemical and biophysical research communications, 2003-06, Vol.306 (1), p.139-143

2003

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Transgenic GLUT-4 overexpression in fat enhances glucose metabolism: preferential effect on fatty acid synthesis

American journal of physiology: endocrinology and metabolism, 1995-05, Vol.268 (5), p.E956-E964

1995

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Both p110α and p110β Isoforms of Phosphatidylinositol 3-OH-Kinase are Required for Insulin Signalling in the Hypothalamus

Journal of neuroendocrinology, 2010-06, Vol.22 (6), p.534-542

2010

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Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle : implications for glucose metabolism

Diabetologia, 1997-10, Vol.40 (10), p.1172-1177

1997

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Phosphoinositide 3-kinase: the protein kinase that time forgot

Biochemical Society transactions, 2004-04, Vol.32 (Pt 2), p.330-331

2004

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The α-isoform of class II phosphoinositide 3-kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs

FEBS letters, 1999-11, Vol.460 (3), p.423-426

1999

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Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: a novel variant with impaired insulin-stimulated lipid kinase activity

Diabetologia, 2000-03, Vol.43 (3), p.321-331

2000

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Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat

Caffeine and theophylline block insulin-stimulated glucose uptake and PKB phosphorylation in rat skeletal muscles

Clozapine directly increases insulin and glucagon secretion from islets: Implications for impairment of glucose tolerance

Dietary supplementation of clinically utilized PI3K p110α inhibitor extends the lifespan of male and female mice

The activation of the Akt/PKB signalling pathway in the brains of clozapine-exposed rats is linked to hyperinsulinemia and not a direct drug effect

Olanzapine effects on body composition, food preference, glucose metabolism and insulin sensitivity in the rat

Mechanisms regulating phosphoinositide 3-kinase signalling in insulin-sensitive tissues

Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue

Saturated-fat diet induces moderate diabetes and severe glomerulosclerosis in hamsters

Glucose Transporters and Insulin Action — Implications for Insulin Resistance and Diabetes Mellitus

Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes

Altered adipocyte properties in the offspring of protein malnourished rats

Microwave Devices, Circuits and Subsystems for Communications Engineering

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

Feeding and glucagon‐like peptide ‐1 receptor activation stabilise β‐catenin in specific hypothalamic nuclei in male rats

Growth factor regulation of the novel class II phosphoinositide 3-kinases

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

TNF-alpha and leptin activate the alpha-isoform of class II phosphoinositide 3-kinase

Transgenic GLUT-4 overexpression in fat enhances glucose metabolism: preferential effect on fatty acid synthesis

Both p110α and p110β Isoforms of Phosphatidylinositol 3-OH-Kinase are Required for Insulin Signalling in the Hypothalamus

Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle : implications for glucose metabolism

Phosphoinositide 3-kinase: the protein kinase that time forgot

The α-isoform of class II phosphoinositide 3-kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs

Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: a novel variant with impaired insulin-stimulated lipid kinase activity

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