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Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients

Acta pharmacologica Sinica, 2020-09, Vol.41 (9), p.1167-1177

2020

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Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice

Acta pharmacologica Sinica, 2021-07, Vol.42 (7), p.1195-1200

2021

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Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor

Acta pharmacologica Sinica, 2021-03, Vol.42 (3), p.482-490

2021

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Recent developments in studies of l-stepholidine and its analogs: chemistry, pharmacology and clinical implications

Current medicinal chemistry, 2007-12, Vol.14 (28), p.2996-3002

2007

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Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects

Acta pharmacologica Sinica, 2022-12, Vol.43 (12), p.3130-3138

2022

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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects

European journal of pharmaceutical sciences, 2023-12, Vol.191, p.106598-106598, Article 106598

2023

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Pharmacokinetics, mass balance, and metabolism of [14C]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension

Acta pharmacologica Sinica, 2023-01, Vol.44 (1), p.221-233

2023

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21 A first-in-human phase 1 study of SIM0417, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects

BMJ paediatrics open, 2024-08, Vol.8 (Suppl 6), p.A9-A10

2024

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Research progress of antipsychotics

Yao hsüeh hsüeh pao, 2016-12, Vol.51 (12), p.1809

2016

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Synthesis of novel analogues of zanamivir as neuraminidase inhibitors

Chinese chemical letters, 2010-11, Vol.21 (11), p.1338-1341

2010

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A practical and enantioselective synthesis of tapentadol

Tetrahedron: asymmetry, 2012-04, Vol.23 (8), p.577-582

2012

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Experimental and theoretical study on the structure and electronic spectra of imiquimod and its synthetic intermediates

Bioorganic & medicinal chemistry letters, 2007-09, Vol.17 (17), p.4942-4946

2007

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Synthesis and Evaluation of PDE5 Inhibitory Activity of Novel Pyrido[2＇,1＇：5,1]pyrazolo[4,3-d]pyrimidin-4-one Derivatives

Chinese journal of chemistry, 2007-02, Vol.25 (2), p.241-245

田广辉夏广新金薇西陈新建赖顺安韦亚兵嵇汝运沈敬山

2007

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Spectroscopic studies of aripiprazole

Guang pu xue yu guang pu fen xi, 2007-05, Vol.27 (5), p.863

2007

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Research progress of anti-influenza virus agents

Yao hsüeh hsüeh pao, 2010-03, Vol.45 (3), p.289

2010

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Signal transduction by protein tyrosine kinases and antitumor agents

Yao hsüeh hsüeh pao, 2008-04, Vol.43 (4), p.323

2008

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Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma

Journal of pharmaceutical and biomedical analysis, 2020-11, Vol.191, p.113634-113634, Article 113634

2020

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Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival

World journal of gastroenterology : WJG, 2014-04, Vol.20 (15), p.4414-4420

2014

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Study on the interaction of anticancer drugs and DNA using fluorescence spectroscopy

Guang pu xue yu guang pu fen xi, 2005-02, Vol.25 (2), p.232

2005

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Design and Synthesis of Pyrido[1,2-e]purin-4(3H)-one Derivatives as Potential PDE 5 Inhibitors

中国化学快报（英文版）, 2005-10, Vol.16 (10), p.1283-1286

2005

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4-Acetyl-2,3,4,5-tetra-hydro-1H-1,4-benzodiazepine

Acta crystallographica. Section E, Structure reports online, 2008-05, Vol.64 (Pt 6), p.o969-o969

2008

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Synthesis of 5-Substituted Hexahydro-1H-1, 4-Diazepine Analogues

中国化学快报(英文版), 2001-11, Vol.12 (11), p.951-954

2001

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Synthesis of 2-Substituted Hexahydro-1H-1,4-diazepine Analogues

中国化学快报(英文版), 2001-03, Vol.12 (3), p.193-194

2001

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3,5‐Dimethoxyacetanilide

Acta crystallographica. Section E, Structure reports online, 2007-06, Vol.63 (6), p.o2782-o2782

2007

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Retrograde approach for the recanalization of coronary chronic total occlusion： preliminary experience of a single center

Chinese medical journal, 2010-04, Vol.123 (7), p.857-863

2010

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Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients

Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice

Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor

Recent developments in studies of l-stepholidine and its analogs: chemistry, pharmacology and clinical implications

Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects

A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects

Pharmacokinetics, mass balance, and metabolism of [14C]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension

21 A first-in-human phase 1 study of SIM0417, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects

Research progress of antipsychotics

Synthesis of novel analogues of zanamivir as neuraminidase inhibitors

A practical and enantioselective synthesis of tapentadol

Experimental and theoretical study on the structure and electronic spectra of imiquimod and its synthetic intermediates

Synthesis and Evaluation of PDE5 Inhibitory Activity of Novel Pyrido[2＇,1＇：5,1]pyrazolo[4,3-d]pyrimidin-4-one Derivatives

Spectroscopic studies of aripiprazole

Research progress of anti-influenza virus agents

Signal transduction by protein tyrosine kinases and antitumor agents

Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma

Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival

Study on the interaction of anticancer drugs and DNA using fluorescence spectroscopy

Design and Synthesis of Pyrido[1,2-e]purin-4(3H)-one Derivatives as Potential PDE 5 Inhibitors

4-Acetyl-2,3,4,5-tetra-hydro-1H-1,4-benzodiazepine

Synthesis of 5-Substituted Hexahydro-1H-1, 4-Diazepine Analogues

Synthesis of 2-Substituted Hexahydro-1H-1,4-diazepine Analogues

3,5‐Dimethoxyacetanilide

Retrograde approach for the recanalization of coronary chronic total occlusion： preliminary experience of a single center

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