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A Novel and Cost Effective Method of Removing Excess Albumin from Plasma/Serum Samples and Its Impacts on LC-MS/MS Bioanalysis of Therapeutic Proteins

Analytical chemistry (Washington), 2014-08, Vol.86 (16), p.8336-8343

2014

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LC-MS/MS determination of apixaban (BMS-562247) and its major metabolite in human plasma: an application of polarity switching and monolithic HPLC column

Bioanalysis, 2014-08, Vol.6 (15), p.2071-2082

2014

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A sensitive liquid chromatography and mass spectrometry method for the determination of posaconazole in human plasma

Journal of pharmaceutical and biomedical analysis, 2007-01, Vol.43 (1), p.228-236

2007

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1β-Hydroxydeoxycholic Acid as an Endogenous Biomarker in Human Plasma for Assessment of CYP3A Clinical Drug–Drug Interaction Potential

Drug metabolism and disposition, 2024-09, Vol.52 (9), p.966-974

2024

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Improved ruggedness of an ion-pairing liquid chromatography/tandem mass spectrometry assay for the quantitative analysis of the triphosphate metabolite of a nucleoside reverse transcriptase inhibitor in peripheral blood mononuclear cells

Rapid communications in mass spectrometry, 2013-02, Vol.27 (3), p.481-488

2013

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A high-throughput LC–MS/MS method for the quantitation of posaconazole in human plasma: Implementing fused core silica liquid chromatography

Journal of pharmaceutical and biomedical analysis, 2009-08, Vol.50 (1), p.46-52

2009

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Orthogonal extraction/chromatography and UPLC, two powerful new techniques for bioanalytical quantitation of desloratadine and 3-hydroxydesloratadine at 25 pg/mL

Journal of pharmaceutical and biomedical analysis, 2006-02, Vol.40 (3), p.689-706

2006

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Minimization of ion suppression in LC–MS/MS analysis through the application of strong cation exchange solid-phase extraction (SCX-SPE)

Journal of pharmaceutical and biomedical analysis, 2005-02, Vol.37 (2), p.359-367

2005

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Strategy for the Quantitation of a Protein Conjugate via Hybrid Immunocapture-Liquid Chromatography with Sequential HRMS and SRM-Based LC-MS/MS Analyses

Analytical chemistry (Washington), 2017-05, Vol.89 (9), p.5144-5151

2017

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Evaluation of automated micro solid phase extraction tips (μ-SPE) for the validation of a LC–MS/MS bioanalytical method

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-11, Vol.843 (2), p.275-282

2006

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Strategies for improving sensitivity and selectivity for the quantitation of biotherapeutics in biological matrix using LC-MS/MS

Expert review of proteomics, 2015-04, Vol.12 (2), p.125-131

2015

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A multiplexed immunocapture liquid chromatography tandem mass spectrometry assay for the simultaneous measurement of myostatin and GDF-11 in rat serum using an automated sample preparation platform

Analytica chimica acta, 2017-08, Vol.979, p.36-44

2017

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A bridging immunogenicity assay for anti-cabiralizumab antibodies: overcoming the low assay cut point and drug tolerance challenges

Bioanalysis, 2021-03, Vol.13 (5), p.395-407

2021

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Selective Reaction Monitoring of Negative Electrospray Ionization Acetate Adduct Ions for the Bioanalysis of Dapagliflozin in Clinical Studies

Analytical chemistry (Washington), 2015-03, Vol.87 (6), p.3247-3254

2015

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Reasons for calibration standard curve slope variation in LC-MS assays and how to address it

Bioanalysis, 2014-06, Vol.6 (11), p.1439-1443

2014

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Dried blood spot analysis without dilution: Application to the LC–MS/MS determination of BMS-986001 in rat dried blood spot

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015-10, Vol.1002, p.201-209

2015

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A validated LC-MS/MS method for the quantitative measurement of creatinine as an endogenous biomarker in human plasma

Bioanalysis, 2016-10, Vol.8 (19), p.1997-2005

2016

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Highly selective and sensitive measurement of active forms of FGF21 using novel immunocapture enrichment with LC-MS/MS

Bioanalysis, 2018-01, Vol.10 (1), p.23-33

2018

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A UHPLC–MS/MS bioanalytical assay for the determination of BMS-911543, a JAK2 inhibitor, in human plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015-06, Vol.991, p.85-91

2015

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Regulated bioanalytical laboratory automation: where we came from, where we are and where we are going

Bioanalysis, 2011-07, Vol.3 (13), p.1415-1418

Shen, Jim X

2011

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Bioanalysis of propylparaben and p-hydroxybenzoic acid, and their sulfate conjugates in rat plasma by liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014-02, Vol.947-948, p.68-74

2014

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Development and validation of a liquid chromatography tandem mass spectrometry assay for the quantitation of a protein therapeutic in cynomolgus monkey serum

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015-04, Vol.988, p.81-87

2015

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Sensitivity-based analytical approaches to support human absolute bioavailability studies

Bioanalysis, 2014-02, Vol.6 (4), p.497-504

2014

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Fit-for-purpose bioanalytical cross-validation for LC-MS/MS assays in clinical studies

Bioanalysis, 2013-01, Vol.5 (1), p.83-90

2013

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Simultaneous determination of desloratadine and pseudoephedrine in human plasma using micro solid-phase extraction tips and aqueous normal-phase liquid chromatography/tandem mass spectrometry

Rapid communications in mass spectrometry, 2007-09, Vol.21 (18), p.3145-3155

2007

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A Novel and Cost Effective Method of Removing Excess Albumin from Plasma/Serum Samples and Its Impacts on LC-MS/MS Bioanalysis of Therapeutic Proteins

LC-MS/MS determination of apixaban (BMS-562247) and its major metabolite in human plasma: an application of polarity switching and monolithic HPLC column

A sensitive liquid chromatography and mass spectrometry method for the determination of posaconazole in human plasma

1β-Hydroxydeoxycholic Acid as an Endogenous Biomarker in Human Plasma for Assessment of CYP3A Clinical Drug–Drug Interaction Potential

Improved ruggedness of an ion-pairing liquid chromatography/tandem mass spectrometry assay for the quantitative analysis of the triphosphate metabolite of a nucleoside reverse transcriptase inhibitor in peripheral blood mononuclear cells

A high-throughput LC–MS/MS method for the quantitation of posaconazole in human plasma: Implementing fused core silica liquid chromatography

Orthogonal extraction/chromatography and UPLC, two powerful new techniques for bioanalytical quantitation of desloratadine and 3-hydroxydesloratadine at 25 pg/mL

Minimization of ion suppression in LC–MS/MS analysis through the application of strong cation exchange solid-phase extraction (SCX-SPE)

Strategy for the Quantitation of a Protein Conjugate via Hybrid Immunocapture-Liquid Chromatography with Sequential HRMS and SRM-Based LC-MS/MS Analyses

Evaluation of automated micro solid phase extraction tips (μ-SPE) for the validation of a LC–MS/MS bioanalytical method

Strategies for improving sensitivity and selectivity for the quantitation of biotherapeutics in biological matrix using LC-MS/MS

A multiplexed immunocapture liquid chromatography tandem mass spectrometry assay for the simultaneous measurement of myostatin and GDF-11 in rat serum using an automated sample preparation platform

A bridging immunogenicity assay for anti-cabiralizumab antibodies: overcoming the low assay cut point and drug tolerance challenges

Selective Reaction Monitoring of Negative Electrospray Ionization Acetate Adduct Ions for the Bioanalysis of Dapagliflozin in Clinical Studies

Reasons for calibration standard curve slope variation in LC-MS assays and how to address it

Dried blood spot analysis without dilution: Application to the LC–MS/MS determination of BMS-986001 in rat dried blood spot

A validated LC-MS/MS method for the quantitative measurement of creatinine as an endogenous biomarker in human plasma

Highly selective and sensitive measurement of active forms of FGF21 using novel immunocapture enrichment with LC-MS/MS

A UHPLC–MS/MS bioanalytical assay for the determination of BMS-911543, a JAK2 inhibitor, in human plasma

Regulated bioanalytical laboratory automation: where we came from, where we are and where we are going

Bioanalysis of propylparaben and p-hydroxybenzoic acid, and their sulfate conjugates in rat plasma by liquid chromatography–tandem mass spectrometry

Development and validation of a liquid chromatography tandem mass spectrometry assay for the quantitation of a protein therapeutic in cynomolgus monkey serum

Sensitivity-based analytical approaches to support human absolute bioavailability studies

Fit-for-purpose bioanalytical cross-validation for LC-MS/MS assays in clinical studies

Simultaneous determination of desloratadine and pseudoephedrine in human plasma using micro solid-phase extraction tips and aqueous normal-phase liquid chromatography/tandem mass spectrometry

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