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Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases

Scientific reports, 2024-06, Vol.14 (1), p.12976-12

2024

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Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (39), p.14295-14300

2014

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Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (52), p.18757-18762

2014

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Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer

Biochemistry (Easton), 2018-02, Vol.57 (6), p.945-962

2018

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Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding

The Journal of biological chemistry, 2011-05, Vol.286 (18), p.16246-16260

2011

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Retinal pathology in the PPCD1 mouse

PloS one, 2017-10, Vol.12 (10), p.e0185094-e0185094

2017

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Familial isolated pituitary adenoma is independent of Ahr genotype in a novel mouse model of disease

Heliyon, 2024-04, Vol.10 (7), p.e28231-e28231, Article e28231

2024

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Molecular mechanism of interactions between ACAD9 and binding partners in mitochondrial respiratory complex I assembly

iScience, 2021-10, Vol.24 (10), p.103153-103153, Article 103153

2021

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The aryl hydrocarbon receptor as a model PAS sensor

Toxicology reports, 2022-01, Vol.9, p.1-11

2022

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Association of a Chromosomal Rearrangement Event with Mouse Posterior Polymorphous Corneal Dystrophy and Alterations in Csrp2bp, Dzank1, and Ovol2 Gene Expression

PloS one, 2016-06, Vol.11 (6), p.e0157577

2016

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Association of Multiple Developmental Defects and Embryonic Lethality with Loss of Microsomal NADPH-Cytochrome P450 Oxidoreductase

The Journal of biological chemistry, 2002-02, Vol.277 (8), p.6536-6541

2002

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Structural and kinetic investigations of the carboxy terminus of NADPH-cytochrome P450 oxidoreductase

Archives of biochemistry and biophysics, 2021-04, Vol.701, p.108792-108792, Article 108792

2021

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Structural and Functional Studies of the Membrane-Binding Domain of NADPH-Cytochrome P450 Oxidoreductase

Biochemistry (Easton), 2019-05, Vol.58 (19), p.2408-2418

2019

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The Toll-like receptor agonist imiquimod is metabolized by aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in human keratinocytes and mouse liver

Archives of toxicology, 2019-07, Vol.93 (7), p.1917-1926

2019

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The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene

PloS one, 2010-08, Vol.5 (8), p.e12213-e12213

2010

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Role of Acidic Residues in the Interaction of NADPH-Cytochrome P450 Oxidoreductase with Cytochrome P450 and Cytochrome c

The Journal of biological chemistry, 1995-11, Vol.270 (46), p.27475-27480

1995

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Differential Contributions of NADPH-Cytochrome P450 Oxidoreductase FAD Binding Site Residues to Flavin Binding and Catalysis

The Journal of biological chemistry, 2000-12, Vol.275 (52), p.41087-41091

2000

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SEA-TROSY (Solvent Exposed Amides with TROSY): A Method to Resolve the Problem of Spectral Overlap in Very Large Proteins

Journal of the American Chemical Society, 2001-05, Vol.123 (19), p.4633-4634

2001

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Mechanistic Studies on the Reductive Half-reaction of NADPH-Cytochrome P450 Oxidoreductase

The Journal of biological chemistry, 1999-02, Vol.274 (9), p.5391-5398

1999

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Preparation and Characterization of a 5‘-DeazaFAD T491V NADPH−Cytochrome P450 Reductase

Biochemistry (Easton), 2003-06, Vol.42 (22), p.6804-6813

2003

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Role of Ser457 of NADPH−Cytochrome P450 Oxidoreductase in Catalysis and Control of FAD Oxidation−Reduction Potential

Biochemistry (Easton), 1996-07, Vol.35 (29), p.9451-9459

1996

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NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.29163

2001

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NADPH-Cytochrome P450 Oxidoreductase

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.29163-29170

2001

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Structure and catalytic mechanism of NADPH-cytochrome P450 oxidoreductase: a prototype of the diflavin oxidoreductase family of enzymes

Handbook of Flavoproteins, 2013, p.73-102

2013

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Human Immunoglobulin D: Genomic Sequence of the Delta Heavy Chain

Science (American Association for the Advancement of Science), 1985-05, Vol.228 (4700), p.733-737

1985

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Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases

Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice

Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase

Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer

Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding

Retinal pathology in the PPCD1 mouse

Familial isolated pituitary adenoma is independent of Ahr genotype in a novel mouse model of disease

Molecular mechanism of interactions between ACAD9 and binding partners in mitochondrial respiratory complex I assembly

The aryl hydrocarbon receptor as a model PAS sensor

Association of a Chromosomal Rearrangement Event with Mouse Posterior Polymorphous Corneal Dystrophy and Alterations in Csrp2bp, Dzank1, and Ovol2 Gene Expression

Association of Multiple Developmental Defects and Embryonic Lethality with Loss of Microsomal NADPH-Cytochrome P450 Oxidoreductase

Structural and kinetic investigations of the carboxy terminus of NADPH-cytochrome P450 oxidoreductase

Structural and Functional Studies of the Membrane-Binding Domain of NADPH-Cytochrome P450 Oxidoreductase

The Toll-like receptor agonist imiquimod is metabolized by aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in human keratinocytes and mouse liver

The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene

Role of Acidic Residues in the Interaction of NADPH-Cytochrome P450 Oxidoreductase with Cytochrome P450 and Cytochrome c

Differential Contributions of NADPH-Cytochrome P450 Oxidoreductase FAD Binding Site Residues to Flavin Binding and Catalysis

SEA-TROSY (Solvent Exposed Amides with TROSY): A Method to Resolve the Problem of Spectral Overlap in Very Large Proteins

Mechanistic Studies on the Reductive Half-reaction of NADPH-Cytochrome P450 Oxidoreductase

Preparation and Characterization of a 5‘-DeazaFAD T491V NADPH−Cytochrome P450 Reductase

Role of Ser457 of NADPH−Cytochrome P450 Oxidoreductase in Catalysis and Control of FAD Oxidation−Reduction Potential

NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer

NADPH-Cytochrome P450 Oxidoreductase

Structure and catalytic mechanism of NADPH-cytochrome P450 oxidoreductase: a prototype of the diflavin oxidoreductase family of enzymes

Human Immunoglobulin D: Genomic Sequence of the Delta Heavy Chain

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