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Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma

Cancer cell, 2013-12, Vol.24 (6), p.710-724

2013

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BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action

Scientific reports, 2016-05, Vol.6 (1), p.25523, Article 25523

2016

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Targeting the DNA Repair Pathway in Ewing Sarcoma

Cell reports (Cambridge), 2014-11, Vol.9 (3), p.829-840

2014

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Orthotopic patient-derived xenografts of paediatric solid tumours

Nature (London), 2017-09, Vol.549 (7670), p.96-100

2017

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A critical evaluation of methods to interpret drug combinations

Scientific reports, 2020-03, Vol.10 (1), p.5144, Article 5144

2020

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Scaffold composition and biological relevance of screening libraries

Nature chemical biology, 2007-08, Vol.3 (8), p.442-446

2007

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Robust Classification of Small-Molecule Mechanism of Action Using a Minimalist High-Content Microscopy Screen and Multidimensional Phenotypic Trajectory Analysis

PloS one, 2016-02, Vol.11 (2), p.e0149439-e0149439

2016

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Identification of small molecule activators of BMP signaling

PloS one, 2013-03, Vol.8 (3), p.e59045

2013

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Discovery of Small Molecules that Inhibit the Disordered Protein, p27Kip1

Scientific reports, 2015-10, Vol.5 (1), p.15686, Article 15686

2015

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Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase

Nature chemical biology, 2017-08, Vol.13 (8), p.850

2017

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An Integrated In Vitro and In Vivo High-Throughput Screen Identifies Treatment Leads for Ependymoma

Cancer cell, 2011-09, Vol.20 (3), p.384-399

2011

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Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs

Angewandte Chemie (International ed.), 2021-12, Vol.60 (51), p.26663-26670

International ed. in English, 2021

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Using response surface models to analyze drug combinations

Drug discovery today, 2021-08, Vol.26 (8), p.2014-2024

2021

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Evaluating and evolving a screening library in academia: the St Jude approach

Drug discovery today, 2021-04, Vol.26 (4), p.1060-1069

2021

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Identification and Characterization of the First Small Molecule Inhibitor of MDMX

The Journal of biological chemistry, 2010-04, Vol.285 (14), p.10786-10796

2010

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Small Molecule Sequestration of the Intrinsically Disordered Protein, p27Kip1, Within Soluble Oligomers

Journal of molecular biology, 2021-09, Vol.433 (18), p.167120-167120, Article 167120

2021

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The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities

Developmental biology, 2016-03, Vol.411 (2), p.287-293

2016

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A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML

Nature communications, 2019-05, Vol.10 (1), p.2189-16, Article 2189

2019

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Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia

Nature communications, 2023-02, Vol.14 (1), p.809-13, Article 809

2023

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Ligand Binding Mode Prediction by Docking: Mdm2/Mdmx Inhibitors as a Case Study

Journal of chemical information and modeling, 2014-02, Vol.54 (2), p.648-659

2014

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MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Nature communications, 2020-02, Vol.11 (1), p.913-20, Article 913

2020

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Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo

Molecular cancer therapeutics, 2023-01, Vol.22 (1), p.37-51

2023

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Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention

Cell reports (Cambridge), 2017-05, Vol.19 (8), p.1640-1653

2017

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Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma

BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action

Targeting the DNA Repair Pathway in Ewing Sarcoma

Orthotopic patient-derived xenografts of paediatric solid tumours

A critical evaluation of methods to interpret drug combinations

Scaffold composition and biological relevance of screening libraries

Robust Classification of Small-Molecule Mechanism of Action Using a Minimalist High-Content Microscopy Screen and Multidimensional Phenotypic Trajectory Analysis

Identification of small molecule activators of BMP signaling

Discovery of Small Molecules that Inhibit the Disordered Protein, p27Kip1

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase

An Integrated In Vitro and In Vivo High-Throughput Screen Identifies Treatment Leads for Ependymoma

Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs

Using response surface models to analyze drug combinations

Evaluating and evolving a screening library in academia: the St Jude approach

Identification and Characterization of the First Small Molecule Inhibitor of MDMX

Small Molecule Sequestration of the Intrinsically Disordered Protein, p27Kip1, Within Soluble Oligomers

The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities

A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML

Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia

Ligand Binding Mode Prediction by Docking: Mdm2/Mdmx Inhibitors as a Case Study

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo

Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention

Chemical genetics of Plasmodium falciparum

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