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RAD6 inhibition enhances paclitaxel sensitivity of triple negative breast cancer cells by aggravating mitotic spindle damage

BMC cancer, 2022-10, Vol.22 (1), p.1-1073, Article 1073

2022

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Surfactant−Polymer Nanoparticles Enhance the Effectiveness of Anticancer Photodynamic Therapy

Molecular pharmaceutics, 2008-09, Vol.5 (5), p.795-807

2008

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Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance

Journal of controlled release, 2010-01, Vol.141 (2), p.137-144

2010

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Rad6B Is a Positive Regulator of β-Catenin Stabilization

Cancer research (Chicago, Ill.), 2008-03, Vol.68 (6), p.1741-1750

2008

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Crosstalk between translesion synthesis, Fanconi anemia network, and homologous recombination repair pathways in interstrand DNA crosslink repair and development of chemoresistance

Mutation research. Reviews in mutation research, 2015-01, Vol.763, p.258-266

2015

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Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization

Nanomedicine, 2016-04, Vol.12 (3), p.745-757

2016

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Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization

Cells (Basel, Switzerland), 2019-11, Vol.8 (11), p.1375

2019

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Environmental Estrogen Stimulation of Growth and Estrogen Receptor Function in Preneoplastic and Cancerous Human Breast Cell Lines

JNCI : Journal of the National Cancer Institute, 1997-12, Vol.89 (23), p.1774-1782

1997

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Inhibition of breast tumor growth and angiogenesis by a medicinal herb: Ocimum gratissimum

International journal of cancer, 2007-08, Vol.121 (4), p.884-894

2007

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RAD6B Loss Disrupts Expression of Melanoma Phenotype in Part by Inhibiting WNT/β-Catenin Signaling

The American journal of pathology, 2021-02, Vol.191 (2), p.368-384

2021

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Utility of DNA postreplication repair protein Rad6B in neoadjuvant chemotherapy response

Medical oncology (Northwood, London, England), 2010-06, Vol.27 (2), p.466-473

2010

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Drug resistance: challenges to effective therapy

Current cancer drug targets, 2011-06, Vol.11 (5), p.613

Shekhar, Malathy P V

2011

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Supramolecular Complex Formation between Rad6 and Proteins of the p53 Pathway during DNA Damage-Induced Response

Molecular and Cellular Biology, 2003-04, Vol.23 (7), p.2463-2475

2003

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Melanoma Development and Progression Are Associated with Rad6 Upregulation and β-Catenin Relocation to the Cell Membrane

Journal of skin cancer, 2014-01, Vol.2014, p.439205-10

2014

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Novel inhibitors of Rad6 ubiquitin conjugating enzyme: design, synthesis, identification, and functional characterization

Molecular cancer therapeutics, 2013-04, Vol.12 (4), p.373-383

2013

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Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin

Biochimica et biophysica acta, 2012-10, Vol.1823 (10), p.1686-1696

2012

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Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (24), p.6886-6889

2013

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Alterations in Galectin-3 Expression and Distribution Correlate with Breast Cancer Progression: Functional Analysis of Galectin-3 in Breast Epithelial-Endothelial Interactions

The American journal of pathology, 2004-12, Vol.165 (6), p.1931-1941

2004

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Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup

Oncotarget, 2013-02, Vol.4 (2), p.231-241

2013

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Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer

Journal of cellular physiology, 2009-05, Vol.219 (2), p.288-300

2009

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Tamoxifen suppresses histologic progression to atypia and DCIS in MCFIOAT xenografts, a model of early human breast cancer

Breast cancer research and treatment, 2001, Vol.65 (1), p.41-47

2001

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Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity

Oncotarget, 2014-02, Vol.5 (4), p.1101-1115

2014

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Host microenvironment in breast cancer development: extracellular matrix-stromal cell contribution to neoplastic phenotype of epithelial cells in the breast

Breast cancer research : BCR, 2003-01, Vol.5 (3), p.130-135, Article 130

2003

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Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation

Cancer research (Chicago, Ill.), 2002-04, Vol.62 (7), p.2115-2124

2002

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Optimised synthesis of diamino-triazinylmethyl benzoates as inhibitors of Rad6B ubiquitin conjugating enzyme

Tetrahedron letters, 2014-12, Vol.55 (51), p.7015-7018

2014

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RAD6 inhibition enhances paclitaxel sensitivity of triple negative breast cancer cells by aggravating mitotic spindle damage

Surfactant−Polymer Nanoparticles Enhance the Effectiveness of Anticancer Photodynamic Therapy

Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance

Rad6B Is a Positive Regulator of β-Catenin Stabilization

Crosstalk between translesion synthesis, Fanconi anemia network, and homologous recombination repair pathways in interstrand DNA crosslink repair and development of chemoresistance

Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization

Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization

Environmental Estrogen Stimulation of Growth and Estrogen Receptor Function in Preneoplastic and Cancerous Human Breast Cell Lines

Inhibition of breast tumor growth and angiogenesis by a medicinal herb: Ocimum gratissimum

RAD6B Loss Disrupts Expression of Melanoma Phenotype in Part by Inhibiting WNT/β-Catenin Signaling

Utility of DNA postreplication repair protein Rad6B in neoadjuvant chemotherapy response

Drug resistance: challenges to effective therapy

Supramolecular Complex Formation between Rad6 and Proteins of the p53 Pathway during DNA Damage-Induced Response

Melanoma Development and Progression Are Associated with Rad6 Upregulation and β-Catenin Relocation to the Cell Membrane

Novel inhibitors of Rad6 ubiquitin conjugating enzyme: design, synthesis, identification, and functional characterization

Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin

Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides

Alterations in Galectin-3 Expression and Distribution Correlate with Breast Cancer Progression: Functional Analysis of Galectin-3 in Breast Epithelial-Endothelial Interactions

Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup

Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer

Tamoxifen suppresses histologic progression to atypia and DCIS in MCFIOAT xenografts, a model of early human breast cancer

Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity

Host microenvironment in breast cancer development: extracellular matrix-stromal cell contribution to neoplastic phenotype of epithelial cells in the breast

Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation

Optimised synthesis of diamino-triazinylmethyl benzoates as inhibitors of Rad6B ubiquitin conjugating enzyme

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