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Spatiotemporal Regulation of Signaling: Focus on T Cell Activation and the Immunological Synapse

International journal of molecular sciences, 2020-05, Vol.21 (9), p.3283

2020

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PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity

Nature communications, 2016-04, Vol.7 (1), p.11366-11366, Article 11366

2016

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Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

Nature chemical biology, 2011-10, Vol.7 (12), p.942-949

2011

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The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

Nature cell biology, 2012-02, Vol.14 (2), p.148-158

2012

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Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119

The EMBO journal, 2012-10, Vol.31 (20), p.4085-4094

2012

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Identification of pyrazolopyridazinones as PDEδ inhibitors

Nature communications, 2016-04, Vol.7 (1), p.11360-11360, Article 11360

2016

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Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling

Science signaling, 2019-02, Vol.12 (567)

2019

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ARL3 activation requires the co-GEF BART and effector-mediated turnover

eLife, 2021-01, Vol.10

2021

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An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism

Nature communications, 2021-03, Vol.12 (1), p.1623-22, Article 1623

2021

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Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3

Biophysical journal, 2015-10, Vol.109 (8), p.1619-1629

2015

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ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition

American journal of human genetics, 2018-10, Vol.103 (4), p.612-620

2018

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The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism

Cell, 2010-05, Vol.141 (5), p.812-821

2010

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Efficacy and safety of sofosbuvir plus daclatasvir or ravidasvir in patients with COVID‐19: A randomized controlled trial

Journal of medical virology, 2021-12, Vol.93 (12), p.6750-6759

2021

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Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity

Nature communications, 2017-02, Vol.8 (1), p.14206-14206, Article 14206

2017

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Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells

AMB Express, 2020-03, Vol.10 (1), p.59-59, Article 59

2020

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The Engineer as Economist: Sewers and the Making of the Water Consumer in Colonial Cairo, 1890

Technology and culture, 2023-04, Vol.64 (2), p.434-455

Ismail, Shehab

2023

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A GDI/GDF-like system for sorting and shuttling ciliary proteins

Small GTPases, 2017-10, Vol.8 (4), p.208-211

Ismail, Shehab

2017

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Post‐proteomic identification of a novel phage‐encoded streptodornase, Sda1, in invasive M1T1 Streptococcus pyogenes

Molecular microbiology, 2004-10, Vol.54 (1), p.184-197

2004

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EPICURES AND EXPERTS: THE DRINKING WATER CONTROVERSY IN BRITISH COLONIAL CAIRO

Arab studies journal, 2018-10, Vol.26 (2), p.8-43

Ismail, Shehab

2018

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EPICURES AND EXPERTS: THE DRINKING WATER CONTROVERSY IN BRITISH COLONIAL CAIRO

Arab studies journal, 2018-10, Vol.26 (2), p.9-43

Ismail, Shehab

2018

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The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms

Biochemistry (Easton), 2021-06, Vol.60 (25), p.1952-1963

2021

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Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1

Structure (London), 2021-03, Vol.29 (3), p.226-237.e4

2021

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Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

Nature (London), 2013-05, Vol.497 (7451), p.638-642

2013

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PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness

The Journal of cell biology, 2021-12, Vol.220 (12), p.1

2021

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Shuttling and sorting lipid-modified cargo into the cilia

Biochemical Society transactions, 2016-10, Vol.44 (5), p.1273-1280

2016

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Spatiotemporal Regulation of Signaling: Focus on T Cell Activation and the Immunological Synapse

PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119

Identification of pyrazolopyridazinones as PDEδ inhibitors

Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling

ARL3 activation requires the co-GEF BART and effector-mediated turnover

An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism

Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3

ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition

The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism

Efficacy and safety of sofosbuvir plus daclatasvir or ravidasvir in patients with COVID‐19: A randomized controlled trial

Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity

Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells

The Engineer as Economist: Sewers and the Making of the Water Consumer in Colonial Cairo, 1890

A GDI/GDF-like system for sorting and shuttling ciliary proteins

Post‐proteomic identification of a novel phage‐encoded streptodornase, Sda1, in invasive M1T1 Streptococcus pyogenes

EPICURES AND EXPERTS: THE DRINKING WATER CONTROVERSY IN BRITISH COLONIAL CAIRO

EPICURES AND EXPERTS: THE DRINKING WATER CONTROVERSY IN BRITISH COLONIAL CAIRO

The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms

Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness

Shuttling and sorting lipid-modified cargo into the cilia

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